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Sylvain Charlat
Chargé de recherche - CNRS
e-mail:
phone: +33 (0)4 72 44 81 01
UMR CNRS 5558 - LBBE
"Biométrie et Biologie Évolutive"
UCB Lyon 1  - Bât. Grégor Mendel
43 bd du 11 novembre 1918
69622 VILLEURBANNE cedex
Building: Mendel 1er étage Office: 122

(More details below on this job !)

Our research deals with various issues in evolutionary biology, most of which are connected with symbiosis and genetic conflicts. Several projects are focused on the horizontal transmission of heritable material, from Wolbachia bacteria to transposable elements or even housekeeping genes: which genomic components can move between branches of the tree of life, at which rate and through which processes? How does the resulting partial evolutionary disconnection affect patterns of conflict or cooperation among these elements? Horizontal transfers also question more generally the sources of heritable variations in fitness, potentially including non-genetic modes of inheritance. I also got interested in the evolutionary implications of these phenomena.

To address these questions, we use genomic approaches applied to large scale samples from natural habitats, from French Polynesia to Costa Rica, as well as modelling.

(full) Publication list

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### More details on our post-doc position ###
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We are seeking a postdoctoral researcher to be hired at the University of Lyon (Biometry and Evolutionary Biology Lab) for three years, starting in September 2019.

The project will deal with horizontal gene transfer in insects and more specifically with the hypothesis that host-parasitoid interactions may constitute a major route for this phenomenon. It builds on a long- term and extensive ecological description of associations between parasitoids and their lepidopteran hosts in a natural area of Costa Rica. Through a collaboration with the University of Pennsylvania and the University of Guelph, we will sequence the full genomes of approximately 200 species from this system to assess if horizontal transfers occur preferentially between insects that are tightly connected through host-parasitoid interactions, or, in the case of Lepidoptera, through the host plants they feed on.

The project will require heavy involvement in bioinformatics and evolutionary biology concepts and methods. The ideal candidate will have a strong interest in horizontal gene transfer, and in evolutionary biology at both molecular and phenotypic levels. He or she should be at ease with bioinformatics, modeling, phylogenetic and co-phylogenetic analysis, and be inspired by the methodological challenges in these fields.

Lyon is a beautiful and lively city, not far from the Alps. The LBBE lab (https://lbbe.univ-lyon1.fr/?lang=en) offers a very active scientific environment, dealing with many current issues in evolutionary biology, from molecules to ecosystems, with diverse approaches, from the bench and the field to big data and pure theory.

Applications should be submitted to Sylvain Charlat <sylvain.charlat@univ-lyon1.fr> by June 1, 2019. Please include your CV and the names of three individuals who are prepared to provide letters of reference. For further details, contact Sylvain or other team members: Julien Varaldi, Vincent Daubin, Vincent Miele, Damien de Vienne (CNRS - University of Lyon), Clement Gilbert (CNRS - Gif sur Yvette), Daniel Janzen (University of Pennsylvania), Paul Hebert (University of Guelph).

+Publications