UMR CNRS 5558 Laboratoire de Biométrie et Biologie Évolutive

article :
Necşulea A, Popa A, Cooper DN, Stenson PD, Mouchiroud D, Gautier C, Duret L (2011)
Meiotic Recombination favors the spreading of deleterious mutations in human populations, Human Mutation, vol. 32 pp.198-206

Palmeira L, Penel S, Lotteau V, Rabourdin-Combe C, Gautier C (2011)
PhEVER: a database for the global exploration of virus-host evolutionary relationships, Nucleic Acids Research, vol. 39 pp.569-575

Veron AS, Lemaitre C, Gautier C, Lacroix V, Sagot M-F (2011)
Close 3D proximity of evolutionary breakpoints argues for the notion of spatial synteny, BMC Genomics, vol. 12(1) pp.1-38

Baudet C, Lemaitre C, Dias Z, Gautier C, Tannier E, Sagot M-F (2010)
Cassis: detection of genomic rearrangement breakpoints, Bioinformatics, vol. 26(15) pp.1897-1898

Brinza L, Calevro F, Duport G, Gaget K, Gautier C, Charles H (2010)
Structure and dynamics of the operon map of Buchnera aphidicola sp. strain APS, BMC Genomics, vol. 11(666) pp.1-16

Degletagne C, Keime C, Rey B, de Dinechin M, Forcheron F, Chuchana P, Jouventin P, Gautier C, Duchamp C (2010)
Transcriptome analysis in non-model species: a new method for the analysis of heterologous hybridization on microarrays, BMC Genomics, vol. 11(344) pp.1-9

Pellet J, Tafforeau L, Lucas-Hourani M, Navratil V, Meyniel L, Achaz G, Guironnet-Paquet A, Aublin-Gex A, Caignard G, Cassonnet P, Chaboud A, Chantier T, Deloire A, Demeret C, Le Breton M, Neveu G, Jacotot L, Vaglio P, Delmotte S, Gautier C, Combet S, Deleage G, Favre M, Tangy T, Jacob M, Andre P, Lotteau V, Rabourdin-Combe C, Vidalain PO (2010)
ViralORFeome: an integrated database to generate a versatile collection of viral ORFs, Nucleic Acids Research, vol. 38 pp.371-378

Braga M, Gautier C, Sagot M-F (2009)
An asymmetric approach to preserve common intervals while sorting by reversals, Algorithms for Molecular Biology, vol. 4(16) pp.1833-1835

Braga MDV, Gautier C, Sagot M-F (2009)
An asymmetric approach to preserve common intervals while sorting by reversals, Algorithms for Molecular Biology, vol. 4(16) pp.1833-1835

Brinza L, Vinuelas J, Cottret L, Calevro F, Rahbé Y, Febvay G, Duport G, Colella S, Rabatel A, Gautier C, Fayard J-M, Sagot M-F, Charles H (2009)
Systemic analysis of the symbiotic function of Buchnera aphidicola the primary endosymbiont of the pea aphid Acyrthosiphon pisum, C.R. Biologies, vol. 332(11) pp.1034-1049

Lemaitre C, Braga Marilia D V , Gautier C, Sagot M-F, Tannier E, Marais GAB (2009)
Footprints of Inversions at Present and Past Pseudoautosomal Boundaries in Human Sex Chromosomes, Genome Biology and Evolution, vol. 1(1) pp.56-66

Lemaitre C, Zaghloul L, Sagot M-F, Gautier C, Arneodo A, Tannier E, Audit B (2009)
Analysis of fine-scale mammalian evolutionary breakpoints provides new insight into their relation to genome organisation, BMC Genomics, vol. 10:335 pp.1-12

Lemaitre C, Tannier E, Gautier C, Sagot M-F (2008)
Precise detection of rearrangement breakpoints in mammalian chromosomes, BMC Bioinformatics, vol. 9 pp.286-322

Melodelima C, Gautier C (2008)
The GC-heterogeneity of teleost fishes, BMC Genomics, vol. 9 pp.1-11

Navratil V, de Chassey B, Meyniel L, Delmotte S, Gautier C, André P, Lotteau V, Rabourdin-Combe C (2008)
VirHostNet: a knowledge base for the management and the analysis of proteome-wide virus-host interaction networks, Nucleic Acids Research, vol. 37 pp.661-668

Navratil V, Penel S, Delmotte S , Mouchiroud D, Gautier C, Aouacheria A (2008)
DigiPINS: A database for vertebrate exonic single nucleotide polymorphisms and its application to cancer association studies, Biochimie, vol. 90 pp.563-569

Soares da Fonseca P, Gautier C, Guimarães Ks, Sagot M-F (2008)
Efficient representation and P-value computation for high-order Markov motifs, Bioinformatics, vol. 24 pp.i160-i166

Aouacheria A, Navratil V, Lopez-Perez R, Gutierrez N C, Churkin A, Barash D, Mouchiroud D, Gautier C (2007)
In silico whole-genome screening for cancer-related single-nucleotide polymorphisms located in human mRNA untranslated regions, BMC Genomics, vol. 8 pp.1-13

Melodelima C, Gautier C, Piau D (2007)
A Markovian approach for the prediction of mouse isochore, Journal of Mathematical Biology, vol. 55 pp.353-364

Truntzer C, Mercier C, Estève J, Gautier C, Roy P (2007)
Importance of data structure in comparing two dimension reduction methods for classification of microarray gene expression data, BMC Bioinformatics, vol. 8 pp.1-12

Aouacheria A, Navratil V, Barthelaix A, Mouchiroud D, Gautier C (2006)
Bioinformatic sreening of human ESTs for differentially expressed genes in normal and tumor tissues, BMC Genomics, vol. 7 pp.1-11

Melodelima C, Guéguen L, Piau D, Gautier C (2006)
A computational prediction of isochores based on hidden Markov models, Gene, vol. 385 pp.41-49

Aouacheria A, Navratil V, Wen W, Jiang M, Mouchiroud D, Gautier C, Gouy M, Zhang M (2005)
In silico whole-genome scanning of cancer-associated nonsynonymous SNPs and molecular characterization of a dynein light chain tumour variant, Oncogene, vol. 24 pp.6133-6142

Gautier C, Navratil V, Melodelima C (2003)
Genomic mapping and molecular processes, , vol. 2 pp.22-28

Bronner G, Spataro B, Gautier C (2002)
Cartographie génomique comparée chez les mammifères, Médecine Science, vol. 18 pp.767-774

Bronner G, Spataro B, Gautier C (2002)
Comparative genomic mapping in mammals, Medecine Science, vol. 18 pp.767-774

Bronner G, Spataro B, Page M, Gautier C, Rechenmann F (2002)
Modeling comparative mapping using objects and associations, Computers and Chemistry, vol. 26 pp.413-420

Piganeau G, Mouchiroud D, Duret L, Gautier C (2002)
Expected Relationship Between the Silent Substitution Rate and the GC Content: Implications for the Evolution of Isochores, Journal of Molecular Evolution, vol. 54 pp.129-133.

Piganeau G, Westrelin R, Tourancheau B, Gautier C (2001)
Multiplicative versus additive selection in relation to genome evolution: a simulation study, Genetical Research, vol. 78 pp.171-175

Gautier C (2000)
Compositional bias in DNA, Current Opinion in Genetics and Development, vol. 10 pp.656-661

Matassi G, Sharp PM, Gautier C (1999)
Chromosomal location effects on gene sequence evolution in mammals, Current biology, vol. 9 pp.786-791

Laurent L, Casale P, Bradai MN, Godley BJ, Gerosa G, Broderick AC, Schroth W, Schierwater B, Levy AM, Freggi D, Abd El-Mawla EM, Hadoud DA, Gomati HE, Domingo M, Hadjichristophorou M, Kornaraky L, Demirayak F, Gautier C (1998)
Molecular resolution of marine turtle stock composition in fishery bycatch: a case study in the Mediterranean, Molecular Biology and Evolution, vol. 7 pp.1529-1542

Montrocher R, Verner M-C, Briolay J, Gautier C, Marmeisse R (1998)
Phylogenetic analysis of the Saccharomyces cerevisiae group based on polymorphisms of rDNA spacer sequences, International Journal of Systematic Bacteriology, vol. 48 pp.295-303

Robinson M, Gouy M, Gautier C, Mouchiroud D (1998)
Sensitivity of the relative-rate test to taxonomic sampling, Molecular Biology and Evolution, vol. 15 pp.1091-1098

Mouchiroud D, Robinson M, Gautier C (1997)
Impact of changes in GC content on the silent molecular clock in murids, Gene, vol. 205 pp.317-322

Robinson M, Gautier C, Mouchiroud D (1997)
Evolution of isochores in rodents, Molecular Biology and Evolution, vol. 14 pp.823-828

Galtier N, Gouy M, Gautier C (1996)
SEAVIEW and PHYLO_WIN: two graphic tools for sequence alignment and molecular phylogeny, Bioinformatics, vol. 12 pp.543-548

Brun C, Julien N, Jacobzone M, Gautier C, Massod R (1995)
SARS ARSS and A T-rich regions evidenced by restriction mapping on an 835-kb DNA fragment from drosophila, Experimental Cell Research, vol. 220 pp.338-347

Duret L, Mouchiroud D, Gautier C (1995)
Statistical analysis of vertebrate sequences reveals that long genes are scarce in GC-rich isochores, Journal of Molecular Evolution, vol. 40 pp.308-317

Mouchiroud D, Gautier C, Bernardi G (1995)
Frequencies of synonymous substitutions in mammals are gene-specific and correlated with frequencies of nonsynonymous substitutions, Journal of Molecular Evolution, vol. 40 pp.107-113

Biémont C, Lemeunier F, Gautier C, Guerreiro MG, Aulard S, Pasyukova EG (1994)
High rate of movement of one (mdg3) out of four transposable elements in a natural population of Drosophila melanogaster, Comptes Rendus de l`Académie des Sciences - Séries III - Sciences de la Vie, vol. 317 pp.213-216

Biémont C, Lemeunier F, Guerreiro MPG, Brookfield JF, Gautier C, Aulard S, Pasyukova EG (1994)
Population dynamics of the copia mdg1 mdg3 gypsy and P transposable elements in a natural population of Drosophila melanogaster, Genetical Research, vol. 63 pp.197-212

Lobry JR, Gautier C (1994)
Hydrophobicity expressivity and aromaticity are the major trends of amino-acid usage in 999 Escherichia coli chromosome-encoded genes, Nucleic Acids Research, vol. 22 pp.3174-3180

Bernardi G, Mouchiroud D, Gautier C (1993)
Silent substitutions in mammalian genomes and their evolutionary implications, Journal of Molecular Evolution, vol. 37 pp.583-589

Duret L, Dorkeld F, Gautier C (1993)
Strong conservation of non-coding sequences during vertebrates evolution: potential involvement in post-transcriptional regulation of gene expression, Nucleic Acids Research, vol. 21 pp.2315-2322

Perrière G, Dorkeld F, Rechenmann F, Gautier C (1993)
Object-oriented knowledge bases for the analysis of prokaryotic and eukaryotic genomes, In Proceedings of the 1st International Conference on Intelligent Systems for Molecular Biology, vol. 1 pp.319-327

Perrière G, Gautier C (1993)
ColiGene: object-centered representation for the study of E coli gene expressivity by sequence analysis, Biochimie, vol. 75 pp.415-422

Schmeltzer O, Medigue C, Uvietta P, Rechenmann F, Dorkeld F, Perrière G, Gautier C (1993)
Building large knowledge bases in molecular biology, In Proceedings of the First International Conference on Intelligent Systems for Molecular Biology, vol. 1 pp.345-353

Aissani B, D`Onofrio G, Mouchiroud D, Gardiner K, Gautier C, Bernardi G (1991)
The compositional properties of human genes, Journal of Molecular Evolution, vol. 32 pp.493-503

D`Onofrio G, Mouchiroud D, Aissani B, Gautier C, Bernardi G (1991)
Correlations between the compositional properties of human genes codon usage and amino acid composition of proteins, Journal of Molecular Evolution, vol. 32 pp.504-510

Mouchiroud D, D`Onofrio G, Aissani B, Macaya G, Gautier C, Bernardi G (1991)
The distribution of genes in the human genome, Gene, vol. 100 pp.181-187

Biémont C, Ronsseray S, Anxolabéhère D, Izaabel H, Gautier C (1990)
Localization of P elements copy number regulation and cytotype determination in Drosophila melanogaster, Genetical Research, vol. 56 pp.3-14

Mouchiroud D, Gautier C (1990)
Codon usage changes and sequence dissimilarity between human and rat, Journal of Molecular Evolution, vol. 31 pp.81-91

Biémont C, Aouar A, Gautier C (1989)
Hybrid viability is correlated with the i-mobile and P-mobile element copy numbers of the maternal inbred line in Drosophila melanogaster, Heredity, vol. 62 pp.301-305

Cortay J C, Bleicher F, Duclos B, Cenatiempo Y, Gautier C, Prato J-L, Cozzone A J (1989)
Utilization of acetate in Escherichia coli: structural organization and differential expression of the ace operon, Biochimie, vol. 71 pp.1043-1049

Gautier C, Bernstein C (1989)
Computer-science and biology, Impact of Science on Society, vol. 39 pp.281-289

Bernardi G, Mouchiroud D, Gautier C (1988)
Compositional patterns in vertebrate genomes: conservation and change in evolution, Journal of Molecular Evolution, vol. 28 pp.7-18

Biémont C, Gautier C (1988)
Localization polymorphism of mdg-1 copia I-mobile-element and P-mobile-element in genome of Drosophila-melanogaster, Heredity, vol. 60 pp.335-346

Biémont C, Gautier C, Heizmann A (1988)
Independent regulation of mobile element copy nimber in Drosophila-melanogaster inbred lines, Chromosoma, vol. 96 pp.291-294

Fichant G, Quentin Y, Gautier C (1988)
(G+C) variation along eukaryotic genomic sequences and chromatine organization, Molecular and Cellular Biology, vol. 7 pp.49-56

Mouchiroud D, Gautier C (1988)
High codon-usage changes in mammalian genes, Molecular Biology and Evolution, vol. 5 pp.192-194

Mouchiroud D, Gautier C, Bernardi G (1988)
The compositional distribution of coding sequences and DNA molecules in humans and murids, Journal of Molecular Evolution, vol. 27 pp.311-320

Biémont C, Gautier C, Heizmann A (1987)
Independent regulation of mobile element copy nimber in Drosophila-melanogaster, Heredity, vol. 58 pp.167-172

Fichant G, Gautier C (1987)
Statistical method for predicting protein coding regions in nucleic acid sequences, Computer Applications in the Biosciences, vol. 3 pp.287-295

Gautier C (1987)
Codon usage changes during evolution - animal mitochondria example, Comptes Rendus de l`Académie des Sciences - Séries III - Sciences de la Vie, vol. 304 pp.123-123

Gautier C, Gouy M, Louail S (1985)
Non-parametric statistics for nucleic acid sequence study, Biochimie, vol. 67 pp.449-453

Gouy M, Gautier C, Attimonelli M, Lanave C, di Paola G (1985)
ACNUC--a portable retrieval system for nucleic acid sequence databases: logical and physical designs and usage, Bioinformatics, vol. 1 pp.167-172

Gouy M, Gautier C, Milleret F (1985)
System analysis and nucleic acid sequence banks, Biochimie, vol. 67 pp.433-436

Grantham R, Greenland T, Louail S, Mouchiroud D, Prato J-L, Gouy M, Gautier C (1985)
Molecular evolution of viruses as seen by nucleic acid sequence study, Bulletin de l’Institut Pasteur, vol. 83 pp.95-148

Gouy M, Milleret F, Mugnier C, Jacobzone M, Gautier C (1984)
ACNUC: a nucleic acid sequence data base and analysis system, Nucleic Acids Research, vol. 12 pp.121-127

Biémont C, Gautier C (1983)
An inbreeding-incompatibility genetic system in Drosophila melanogaster and its frequency in natural populations, Genetica, vol. 61 pp.191-195

Gouy M, Gautier C (1982)
Codon usage in bacteria: correlation with gene expressivity, Nucleic Acids Research, vol. 10 pp.7055-7074

Grantham R, Gautier C, Gouy M, Jacobzone M, Mercier R (1981)
Codon catalog usage is a genome strategy modulated for gene expressivity, Nucleic Acids Research, vol. 9 pp.R43-R74

Grantham R, Gautier C (1980)
Genetic distances from mRNA sequences, Naturwissenschaften, vol. 67 pp.93-94

Grantham R, Gautier C, Gouy M (1980)
Codon frequencies in 119 individual genes confirm consistent choices of degenerate bases according to genome type, Nucleic Acids Research, vol. 8 pp.1893-1912

Grantham R, Gautier C, Gouy M, Mercier R, Pave A (1980)
Codon catalog usage and the genome hypothesis, Nucleic Acids Research, vol. 8 pp.R49-R62

Gautier C (1979)
Analysis of presence-absence grids monospecific and multispecific cases, Oecologia Plantarum, vol. 14 pp.251-251

Cheruy A, Gautier C, Pavé A (1978)
Analyse des systèmes biologiques: certains aspects méthodologiques liés à la modélisation, ATP Analyse des Systèmes, vol. pp.1-71

Chessel D, Gautier C (1977)
Des statistiques non paramétriques pour l`analyse des données binaires, Revue de statistique appliquée, vol. 25 pp.57-73

Gautier C (1977)
Directional mutation-rates measure of protein evolution, Année Biologique, vol. 16 pp.1-39

Gautier C (1976)
Average proteins and the genetic code, Science, vol. 194 pp.642-643

book :
Gautier C, Gouy M, Jacobzone M, Grantham R (1981)
Nucleic acid sequences handbook, Praeger, 1981

inbook :
Duret L, Bataillon T, Bierne N, Daubin V, Dutheil J, Gautier C, Glémin S, Gouy M, Heyer E, Marais G, Mouchiroud D, Pontarroti P, Quintana-Murci L, Robinson-Rechavi M, Galtier N (2010)
Evolution Moléculaire, , vol. pp.114-173

inproceedings :
Melodelima C, Gautier C (2007)
Markovian approach for the segmentation of the chimpanzee genome, Proceeding of BIRD`07, , Lecture notes in Bioinformatics, vol. 4414 pp.251-262

Melodelima C, Guéguen L, Gautier C, Piau D (2006)
A Markovian Approach for the Analysis of the Gene Structure, Proceedings of the Prague Stringology Conference, , vol. 19(1) pp.19-35

Gautier C, Navratil V, Melodelima C (2004)
Genomic Information along the Genome: Modeling Statistical analysis and Evolutionary Implication, IFIP World Computer Congress (18th), pp.22-28