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Service de Pharmacologie Clinique - UMR 5558 Faculté de Médecine Laennec Rue Guillaume Paradin BP8071 69376 LYON cedex 08
+Publications -Publications
article :
Boussageon R, Supper I, Bejan-Angoulvant T, Kellou N, Cucherat M, Boissel J-P, Kassai B, Moreau A, Gueyffier F, Cornu C (2012)
Reappraisal of Metformin Efficacy in the Treatment of Type 2 Diabetes: A Meta-Analysis of Randomised Controlled Trials, PLoS Med, vol. 9 pp.347-351
Bonnefoy M, Boutitie F, Mercier C, Gueyffier F, Carré C, Guetemme G, Ravis B, Laville M, Cornu C (2011)
EFFICACY OF A HOME-BASED INTERVENTION PROGRAMME ON THE PHYSICAL ACTIVITY LEVEL AND FUNCTIONAL ABILITY OF OLDER PEOPLE USING DOMESTIC SERVICES: A RANDOMISED STUDY, The Journal of Nutrition Health and Aging, vol. pp.1-8
Boussageon R, Bejan-Angoulvant T, Saadatian-Elahi M, Lafont S, Bergeonneau C, Kassaï B, Erpeldinger S, Wright JM, Gueyffier F, Cornu C (2011)
Effect of intensive glucose lowering treatment on all cause mortality cardiovascular death and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials, British Medical Journal, vol. 343 pp.1-12
Gueyffier F, Perez MI, Wright JM, Marchant I, Musini VM, Bejan-Angoulvant T (2011)
Blood pressure lowering in the oldest old: a step toward abandoning arbitrary blood pressure targets, Journal of Hypertension, vol. 29 pp.171-175
Guignant C, Lepage C, Huang X, Kherouf H, Denis L, Poitevin F, Malcus C, Chéron A, Allaouchiche B, Gueyffier F, Ayala A, Monneret G, Venet F (2011)
Programmed death-1 levels correlate with increased mortality nosocomial infection and immune dysfunctions in septic shock patients, BioMed Central, vol. 15(R99) pp.1-11
Marchant I, Nony P, Cucherat M, Boissel J-P, Thomas SR, Bejan-Angoulvant T, Laugerotte A, Kahoul R, Gueyffier F (2011)
The Global Risk Approach Should Be Better Applied in French Hypertensive Patients: A Comparison between Simulation and Observation Studies, PLoS ONE, vol. 6(3) pp.1-7
Bejan-Angoulvant T, Saadatian-Elahi M, Wright JM, Schron EB, Lindholm LH, Fagard R, Staessen JA, Gueyffier F (2010)
Treatment of hypertension in patients 80 years and older: the lower the better? A meta-analysis of randomized controlled trials, Journal of Hypertension, vol. 28 pp.1366-1372
Domenech C, Thomas X, Chabaud S, Baruchel A, Gueyffier F, Mazingue F, Auvrignon A, Corm S, Dombret H, Chevallier P, Galambrun C, Huguet F, Legrand F, Mechinaud F, Vey N, Philip I, Liens D, Godfrin Y, Rigal D, Bertrand Y (2010)
L-asparaginase loaded red blood cells in refractory or relapsing acute lymphoblastic leukaemia in children and adults: results of the GRASPALL 2005-01 randomized trial, British Journal of Haematology, vol. pp.1-8
Cottraux J, Druon Note I, Boutitie F, Milliery M, Genouihlac V, Yao SN, Note B, Mollard E, Bonasse F, Gaillard S, Djamoussian D, C de Mey, Culem A, Gueyffier F (2009)
Cognitive Therapy versus Rogerian Supportive Therapy in Borderline Personality Disorder, Psychotherapy and psychosomatics, vol. 78(5) pp.307-316
Kassai B, Gueyffier F, Rabilloud M (2009)
Fondements de l`évaluation des tests diagnostiques, Lecture critique d`article, vol. 59 pp.375-379
Marchant I, Boissel J-P, Kassaï B, Bejan-Angoulvant T, Massol J, Vidal C, Amsallem E, Naudin F, Galan P, Czernichow S, Nony P, Gueyffier F (2009)
SCORE should be preferred to Framingham to predict cardiovascular death in French population, European Journal of cardiovascular prevention & rehabilitation, vol. 16(5) pp.609-615
Planchamp F, Nguyen K-A, Vial T, Nasri S, Javouhey E, Gillet Y, Ranchin B, Villard F, Floret D, Cochat P, Gueyffier F, Kassaï B (2009)
Recueil systématique et actif des evènements indésirables médicamenteux chez les enfants admis aux urgences pédiatriques, Archives de Pédiatrie, vol. 16(2) pp.106-111
Boissel J-P, Cucherat M, Nonyc P, Chabaud S, Gueyffier F, Wright JM, Lièvre M, Leizorovicz A (2008)
New insights on the relation between untreated and treated outcomes for a given therapy effect model is not necessarily linear, Journal of Clinical Epidemiology, vol. 61(3) pp.301-307
Boussageon R, Gueyffier F, Bejan-Angoulvant T, Felden-Dominiak G (2008)
Critique du modèle additif de l`essai clinique randomisé, Thérapie, vol. 63(1) pp.29-35
Riley RD, Lambert PC, Staessen JA, Wang J, Gueyffier F, Thijs L, Boutitie F (2008)
Meta-analysis of continuous outcomes combining individual patient data and aggregate data, Statistics in Medicine, vol. 27(11) pp.1870-1893
Boussageon R, Gueyffier F, Moreau A, Gansel Y, Boussageon V (2007)
Some reflexions about double blind, Encephale-Revue de Psychiatrie clinique biologique et therapeutique, vol. 34(4) pp.347-351
Boutitie F, Gueyffier F, Achard JM (2007)
The JIKEI trial, Lancet, vol. 370 pp.1825-1826
Boutitie F, Oprisiu R, Achard JM, Mazouz H, Wang J, Messerli FH, Gueyffier F, Fournier A (2007)
Does a change in angiotensin-II-formation caused by antihypertensive drugs affect the risk of stroke ? A meta-analysis of trials according to treatment with potentially different effects on angiotensin-II, Journal of Hypertension, vol. 25 pp.1543-1553
Gueyffier F, Bejan-Angoulvant T (2007)
Do We Need to Assess the Effect of Treatment Withdrawal? The Paradigm of Life-Long Prevention, Journal of the American Hearth Association, vol. pp.219-226
Kassaï B, Chiron C, Augier S, Cucherat M, Rey E, Gueyffier F, Guerrini R, Vincent J, Dulac O, Pons G (2007)
Severe myoclonic epilepsy in infancy: A systematic review and a meta-analysis of individual patient data, Epilepsia, vol. 48 pp.1-6
Kassaï B, Gueyffier F, Boissel J-P (2007)
Critères intermédiaires et critères de substitution, Médecine thérapeutique, vol. 13(4) pp.279-286
Atoui H, Fayn J, Gueyffier F, Rubel P (2006)
Cardiovascular Risk Stratification in Decision Support Systems: A Probabilistic Approach. Application to pHealth, Computers in Cardiology, vol. 33 pp.281-284
Gueyffier F, Wright JM (2006)
Estimation of attributable burden of disease: authors’ reply, Journal of Hypertension, vol. 24(5) pp.171-175
Gueyffier F, Wright JM (2006)
The lower the better: Does simplicity lead to absurdity?, Editorial comment, vol. 24(3) pp.431-433
Monneret G, Lepape A, Voirin N, Bohé J, Venet F, Debard A-L, Thizy H, Bienvenu J, Gueyffier F, Vanhems P (2006)
Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock, Intensive Care Medicine, vol. 32 pp.1175-1183
Nguyen K-A, Vial T, Gueyffier F, Marignier S, Cochat P, Kassaï B (2006)
Safety of computerized drug management: a case report, British Journal of Clinical Pharmacology, vol. 63 pp.245-246
Barna A, Baudet M, Cambou J-P, Chatellier G, Cucherat M, Dallongeville J, Durlach V, Giral P, Gueyffier F, Kownator S, Lang T, Léonard D, Pace E, Paillard F, Vallée J-P, Vergès B, Aquino J-P , Aulanier S, Balarac N, Beucler I, Bobrie G, Caporossi L, Dénolle T, D`Ivernois C, Dumarcet N, Erpeldinger S, Farnier M, Ferrières J, Fischer C, Friocourt P, Girerd X, Godin M, Halimi S, Jean T, Lièvre M, Loirat P, Lucas C, Marechaud R, Marre M, Ménard J, Mimran A, Moulin P, Picard S, Poncelet P, Pouchain D, Scarabin P-Y, Seux M-L, Senechal M, Sicard D, Turpin G, Vaisse B, Vallée J (2005)
Methods for evaluation of total cardiovascular risk, Médecine thérapeutique, vol. 11 pp.233-236
Boissel J-P, Gueyffier F, Boutitie F, Pocock S, Fagard R (2005)
Apparent effect on blood pressure is only partly responsible for the risk reduction due to antihypertensive treatments, Fundamental & Clinical Pharmacology, vol. 19 pp.579-584
Kassaï B, Boissel J-P, Cucherat M, Boutitie F, Gueyffier F (2005)
Treatment of high blood pressure and gain in event-free life expectancy, Vascular health and risk management, vol. 1 pp.163-169
Kassaï B, Shah NR, Leizorovicz A, Cucherat M, Gueyffier F, Boissel J-P (2005)
The true treatment benefit is unpredictable in clinical trials using surrogate outcome measured with diagnostic tests, Journal of Clinical Epidemiology, vol. 58 pp.1042-1051
Wang J-G, Staessen JA, Franklin S, Fagard R, Gueyffier F (2005)
Systolic and Diastolic Blood Pressure Lowering as Determinants of Cardiovascular Outcome, Hypertension, vol. 45(5) pp.907-913
Boissel J-P, Gueyffier F, Cucherat M, Bricca G (2003)
Pharmacogenetics and responders to a therapy: Theoretical background and practical problems, Clinical Chemistry and Laboratory Medicine, vol. 41 pp.564-572
Boissel J-P, Haugh M, Fardeheb M, Nony P, Gueyffier F, Strang N (2003)
How should therapeutic information be transferred to users?, Fundamental & Clinical Pharmacology, vol. 17 pp.495-503
Cornu C , Carré C, Guetemme G, Ravis B, Thérond S, Gueyffier F, Bonnefoy M (2003)
Prévention de la dépendance des personnes âgées : étude randomisée dans la communauté Prevention of Dependency in Elderly Persons: A Randomised Study in the Community, Thérapie, vol. 89 pp.731-9
Gueyffier F, Cucherat M (2003)
"Causality and statistical association (2) Mechanical determinism and stochastic model", La Revue du praticien, vol. 53 pp.933-936
Kassaï B, Gueyffier F, Boissel J-P, Boutitie F, Cucherat M (2003)
Absolute benefit number needed to treat and gain in life expectancy: which efficacy indices for measuring the treatment benefit?, Journal of Clinical Epidemiology, vol. 56 pp.977-982
