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The software package HiFiX implements the novel algorithm for HIgh FIdelity Clustering of Sequences.

To tackle the challenge of finding proteins families, we model the
all-against-all comparison between proteins by a similarity network.
HiFiX combines network topology analysis where sequence similarity is seen as a social relationship, multiple alignment quality measurement and model selection theory.

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HiFiX supports multiprocessing and is therefore fast enough to be used in practice
on large amounts of data.

HiFiX is already included in the experimental pipeline for HOGENOM.