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le lundi 12 avril à 11:00

Margaret McFall-Ngai

Amphi 5, Déambulatoire du bâtiment Mendel

par Vincent Daubin - 12 avril 2010

"The common language of mutualism and pathogenic animal-microbial associations : Lessons from the squid-vibrio system"

One of the principal questions in the study of animal-bacterial
interactions is : What are the cellular and molecular differences
between beneficial and pathogenic associations ? The study of several
invertebrate symbioses has demonstrated that, although the outcomes
are different, beneficial and pathogenic assocations share much of
the same molecular language. This presentation will focus upon
contributions to the field made by the study of the relationship
between the Hawaiian bobtail squid Euprymna scolopes and its luminous
bacterial partner Vibrio fischeri. In this symbiosis, the bacteria
are acquired anew each generation and form persistent interactions
along the apical surfaces of host epithelia, a pattern of symbiosis
that is perhaps the most widespread among animals. The mechanisms
underlying the processes of host-symbiont recognition, induction of
partner development, and the maintenance of a balanced relationship
will be highlighted.