Septembre
Christopher Sauvage (INRA Montfavet)
Salle de conférence du batiment l’Herbier
Transcriptomic rewiring induced by domestication : a case study in tomato
Jian Lu (Center of Bioinformatics, Peking University, China)
Salle de formation du PRABI
Adaptation of A-to-I RNA editing and the impact on genome evolution
Adenosine-to-inosine (A-to-I) editing is hypothesized to facilitate adaptive evolution by expanding proteomic diversity through an epigenetic approach. However, it is challenging to provide evidences to support this hypothesis at the whole editome level. In this study, we systematically characterized 2,114 A-to-I RNA editing sites in female and male brains of D. melanogaster, and nearly half of these sites had events (...)
Séminaire Biostatistique - Pr B. RACHET
erence and mediation analysis : an overview of the principles and assumptions
Randomised clinical trials (RCTs) are the gold standard to make causal inference on associations between an exposure/treatment variable and an outcome. However, RCTs are not (ethically or practically) feasible in many situations. Using the counterfactuals or the potential outcomes, important conceptual development has been conducted in the last decades around causal inference derived from observational data.
The (...)
