Recherche avancée
Affichage des résultats 3841 à 3860 sur 8428 au total
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Population pharmacokinetics of teicoplanin administered by subcutaneous or intravenous route and simulation of optimal loading dose regimen
Yoann Cazaubon, Nicolas Venisse, Olivier Mimoz, Pascal Maire, Michel Ducher, Laurent Bourguignon, Sylvain Goutelle
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Mechanisms of drug-drug interaction between rifampicin and fusidic acid
Florianne Bel, Laurent Bourguignon, Michel Tod, Tristan Ferry, Sylvain Goutelle
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Quantitative Prediction of Drug-Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is it Worth It?
M Tod, Sylvain Goutelle, L Bourguignon, N Bleyzac
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Prevalence and Risk Factors of Drug-Associated Corrected QT Prolongation in Elderly Hospitalized Patients: Results of a Retrospective Analysis of Data Obtained Over 6 Months
O. Maison, B. de La Gastine, L. Dayot, Sylvain Goutelle
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Is Trough Concentration of Vancomycin Predictive of the Area Under the Curve? A Clinical Study in Elderly Patients
A. Bel Kamel, Laurent Bourguignon, M. Marcos, M. Ducher, Sylvain Goutelle
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Implications of using the MDRD or CKD-EPI equation instead of the Cockcroft-Gault equation for estimating renal function and drug dosage adjustment in elderly patients
E. Cartet-Farnier, L. Goutelle-Audibert, P. Maire, B. de La Gastine, Sylvain Goutelle
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The Role of Antibiotics in Modulating Virulence in Staphylococcus aureus
Elisabeth Hodille, Warren Rose, Binh An Diep, Sylvain Goutelle, Gérard Lina, Oana Dumitrescu
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A Model for Predicting the Interindividual Variability of Drug-Drug Interactions
M. Tod, Laurent Bourguignon, N. Bleyzac, Sylvain Goutelle
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A Nonparametric Method to Optimize Initial Drug Dosing and Attainment of a Target Exposure Interval: Concepts and Application to Busulfan in Pediatrics
M. Philippe, M. Neely, Y. Bertrand, N. Bleyzac, Sylvain Goutelle
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Factors associated with changes in exposure to anticholinergic and sedative medications in elderly hospitalized patients: multicentre longitudinal study
V. Dauphinot, R. Faure, L. Bourguignon, Sylvain Goutelle, P. Krolak-Salmon, C. Mouchoux
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Pharmacokinetics of Vancomycin in Elderly Patients Aged over 80 Years
Laurent Bourguignon, Yoann Cazaubon, Guillaume Debeurme, Constance Loue, Michel Ducher, Sylvain Goutelle
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Improved outcome of children transplanted for high-risk leukemia by using a new strategy of cyclosporine-based GVHD prophylaxis
N Bleyzac, D Cuzzubbo, C Rénard, N Garnier, V Dubois, C Domenech, M-P Goutagny, A Plesa, N Grardel, Sylvain Goutelle, A Janoly-Duménil, Y Bertrand
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Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers
L. Gabriel, M. Tod, Sylvain Goutelle
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Accurately Achieving Target Busulfan Exposure in Children and Adolescents With Very Limited Sampling and the BestDose Software
M. Neely, M. Philippe, T. Rushing, X. Fu, M. van Guilder, D. Bayard, A. Schumitzky, N. Bleyzac, Sylvain Goutelle
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Comparison of the static in vivo approach to a physiologically based pharmacokinetic approach for metabolic drug-drug interactions prediction
M. Tod, P.B. Pierrillas, Laurent Bourguignon, Sylvain Goutelle
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Pharmacokinetic Variability of Daptomycin during Prolonged Therapy for Bone and Joint Infections
Sylvain Goutelle, Sandrine Roux, Marie-Claude Gagnieu, Florent Valour, Sebastien Lustig, Florence Ader, Frédéric Laurent, Christian Chidiac, Tristan Ferry
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Mathematical modeling and systems pharmacology of tuberculosis: Isoniazid as a case study
L. Lalande, Laurent Bourguignon, P. Maire, Sylvain Goutelle
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Should busulfan therapeutic range be narrowed in pediatrics? Experience from a large cohort of hematopoietic stem cell transplant children
M. Philippe, Sylvain Goutelle, J. Guitton, X. Fonrose, C. Bergeron, Pascal Girard, Y. Bertrand, N. Bleyzac
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Pharmacokinetic and Analytical Issues in Busulfan Area Under the Curve Estimation and Simulation
Michael Philippe, Nathalie Bleyzac, Sylvain Goutelle
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Are ciprofloxacin dosage regimens adequate for antimicrobial efficacy and prevention of resistance? Pseudomonas aeruginosa bloodstream infection in elderly patients as a simulation case study
Yoann Cazaubon, Laurent Bourguignon, Sylvain Goutelle, Olivier Martin, Pascal Maire, Michel Ducher