Recherche avancée
Affichage des résultats 5681 à 5700 sur 6933 au total
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Evaluation of various gentamicin dosage regimens in geriatric patients: a simulation study
Laurent Bourguignon, Sylvain Goutelle, J. Burdin de Saint Martin, P. Maire, M. Ducher
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Quantitative prediction of cytochrome P450(CYP) 2D6-Mediated drug interactions
Michel Tod, Sylvain Goutelle, F. Clavel-Grabit, G. Nicolas, B. Charpiat
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Genotype-Based Quantitative Prediction of Drug Exposure for Drugs Metabolized by CYP2D6
Michel Tod, Sylvain Goutelle, M.C. Gagnieu, Working Group The Genophar Ii
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Mathematical modeling of pulmonary tuberculosis therapy: Insights from a prototype model with rifampin
Sylvain Goutelle, Laurent Bourguignon, R-W. Jelliffe, J.E. Conte, P. Maire
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Mathematical modeling of pulmonary tuberculosis therapy: insights from a prototype model with rifampin
Sylvain Goutelle, Laurent Bourguignon, Roger W. Jelliffe, John E. Conte, Pascal Maire
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Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children
E. Bernard, Sylvain Goutelle, Y. Bertrand, Nathalie Bleyzac
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Pharmacokinetic Drug Interaction Between Cyclosporine and Imatinib in Bone Marrow Transplant Children and Model-Based Reappraisal of Imatinib Drug Interaction Profile
Nathalie Bleyzac, K. Kebaili, V. Mialou, Y. Bertrand, Sylvain Goutelle
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Exposure to anticholinergic and sedative drugs, risk of falls, and mortality: an elderly inpatient, multicenter cohort
V. Dauphinot, R. Faure, S. Omrani, Sylvain Goutelle, Laurent Bourguignon, P. Krolak-Salmon, C. Mouchoux
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Determinants of torsades de pointes in older patients with drug-associated long QT syndrome: a case-control study
Sylvain Goutelle, E. Sidolle, M. Ducher, J. Caron, Q. Timour, Patrice Nony, A. Gouraud
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Influence of renal function estimation on pharmacokinetic modeling of vancomycin in elderly patients
A. Glatard, Laurent Bourguignon, R. W. Jelliffe, P. Maire, M. N. Neely, Sylvain Goutelle
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Comparison of the static in vivo approach to a physiologically based pharmacokinetic approach for metabolic drug-drug interactions prediction
M. Tod, P.B. Pierrillas, Laurent Bourguignon, Sylvain Goutelle
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Pharmacokinetic Variability of Daptomycin during Prolonged Therapy for Bone and Joint Infections
Sylvain Goutelle, Sandrine Roux, Marie-Claude Gagnieu, Florent Valour, Sebastien Lustig, Florence Ader, Frédéric Laurent, Christian Chidiac, Tristan Ferry
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Prevalence and Risk Factors of Drug-Associated Corrected QT Prolongation in Elderly Hospitalized Patients: Results of a Retrospective Analysis of Data Obtained Over 6 Months
O. Maison, B. de La Gastine, L. Dayot, Sylvain Goutelle
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A Nonparametric Method to Optimize Initial Drug Dosing and Attainment of a Target Exposure Interval: Concepts and Application to Busulfan in Pediatrics
M. Philippe, M. Neely, Y. Bertrand, N. Bleyzac, Sylvain Goutelle
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Mechanisms of drug-drug interaction between rifampicin and fusidic acid
Florianne Bel, Laurent Bourguignon, Michel Tod, Tristan Ferry, Sylvain Goutelle
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Population pharmacokinetics of teicoplanin administered by subcutaneous or intravenous route and simulation of optimal loading dose regimen
Yoann Cazaubon, Nicolas Venisse, Olivier Mimoz, Pascal Maire, Michel Ducher, Laurent Bourguignon, Sylvain Goutelle
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Assessing the Combined Antibacterial Effect of Isoniazid and Rifampin on Four Mycobacterium tuberculosis Strains Using In Vitro Experiments and Response-Surface Modeling
Charlotte Genestet, Florence Ader, Catherine Pichat, Gérard Lina, Oana Dumitrescu, Sylvain Goutelle
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Population Pharmacokinetics and Dosing Simulation of Vancomycin Administered by Continuous Injection in Critically Ill Patient
Romain Garreau, Benoît Falquet, Lisa Mioux, Laurent Bourguignon, Tristan Ferry, Michel Tod, Florent Wallet, Arnaud Friggeri, Jean-Christophe Richard, Sylvain Goutelle
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Virtual screening of GPCRs: An in silico chemogenomics approach
Laurent Jacob, Brice Hoffmann, Véronique Stoven, Jean-Philippe Vert
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Machine learning for in silico virtual screening and chemical genomics: new strategies.
Jean-Philippe Vert, Laurent Jacob