GECO Evolutionary and Computational Genomics

Bioinformatics, Phylogeny and Evolutionary Genomics Group

Baobab Group

The main goal of the GECO department is to foster integration and synergies between theoretical and methodological research relevant for the analysis of genomes (computational genomics) and empirical analysis of genomic and multi-omic data (evolutionary and functional genomics). The department is structured in two teams, BAOBAB and BPGE:

BAOBAB is deeply rooted in computer science. Its strengths are in algorithms, models, and mathematical analysis of graphs and networks, with applications to transcriptomics and metabolic networks.

BPGE is oriented towards bioinformatics, phylogenetics and evolutionary genomics. Its research projects cover a broad range of subjects, such as methodological developments for phylogenetic inference, their applications to the reconstruction of the evolutionary history of bacteria and archaea, the role of mobile genetic elements in the evolution of bacteria and of antibioresistance, or the role of recombination, of genomic rearrangements and of transposable elements in the evolution of eukaryotic genomes.

As detailed on their pages, the research conducted in both teams integrates deep and long-ranging theoretical and methodological (algorithmic and computational) developments with data analysis driven by empirical questions. This integration is bi-directional: methodological developments are guided by empirical questions and then used in empirical applications, while theoretical modeling helps clarify the conceptual basis of subsequent empirical analyses.

Publications

Display of 241 to 270 publications on 1415 in total

Population genomics supports clonal reproduction and multiple independent gains and losses of parasitic abilities in the most devastating nematode pest

Georgios Koutsovoulos, Eder Marques, Marie Jeanne Arguel, Laurent Duret, Andressa C. Z. Machado, Regina M. D. G. Carneiro...

Evolutionary Applications . 13 : 442-457

DOI: 10.1111/eva.12881

Journal article

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Capybara: equivalence ClAss enumeration of coPhylogenY event-BAsed ReconciliAtions

Yishu Wang, Arnaud Mary, Marie-France Sagot, Blerina Sinaimeri

Bioinformatics . 36 ( 14 ) : 4197-4199

DOI: 10.1093/bioinformatics/btaa498

Journal article

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Algorithms for the quantitative Lock/Key model of cytoplasmic incompatibility

Tiziana Calamoneri, Mattia Gastaldello, Arnaud Mary, Marie-France Sagot, Blerina Sinaimeri

Algorithms for Molecular Biology . : 1-16

DOI: 10.1186/s13015-020-00174-1

Journal article

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From conservation to structure, studies of magnetosome associated cation diffusion facilitators (CDF) proteins in Proteobacteria

Keren-Khadmy Noa, Natalie Zeytuni, Nitzan Kutnowski, Guy Perriere, Caroline Monteil, Raz Zarivachid

PLoS ONE . 15 ( 4 ) : e0231839

DOI: 10.1371/journal.pone.0231839

Journal article

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Isotopic systematics point to wild origin of mummified birds in Ancient Egypt

Marie Linglin, Romain Amiot, Pascale Richardin, Stéphanie Porcier, Ingrid Antheaume, Didier Berthet...

Scientific Reports . 10 ( 1 )

DOI: 10.1038/s41598-020-72326-7

Journal article

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The Gauls experienced the Roman Warm Period: Oxygen isotope study of the Gallic site of Thézy-Glimont, Picardie, France

Thibault Clauzel, Pascale Richardin, Jannick Ricard, Yves Le Béchennec, Romain Amiot, François Fourel...

Journal of Archaeological Science: Reports . 34 : 102595

DOI: 10.1016/j.jasrep.2020.102595

Journal article

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Metapopulation ecology links antibiotic resistance, consumption, and patient transfers in a network of hospital wards

Julie Teresa Shapiro, Gilles Leboucher, Anne-Florence Myard-Dury, Pascale Girardo, Anatole Luzzati, Mélissa Mary...

eLife . 9

DOI: 10.7554/eLife.54795

Journal article

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Dickeya poaceiphila sp. nov., a plant-pathogenic bacterium isolated from sugar cane (Saccharum officinarum)

Nicole Hugouvieux-Cotte-Pattat, Celine Brochier-Armanet, Jean-Pierre Flandrois, Sylvie Reverchon

International Journal of Systematic and Evolutionary Microbiology . 70 ( 8 ) : 4508-4514

DOI: 10.1099/ijsem.0.004306

Journal article

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δ18O and δ13C of diagenetic land snail shells from the Pliocene (Zanclean) of Lanzarote, Canary Archipelago: Do they still record some climatic parameters?

Christophe Lécuyer, Antonio Sanchez Marco, Alejandro Lomoschitz, Juan-Francisco Betancort, François Fourel, Romain Amiot...

Journal of African Earth Sciences . 162 : 103702

DOI: 10.1016/j.jafrearsci.2019.103702

Journal article

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Clinical interpretation of variants identified in RNU4ATAC, a non-coding spliceosomal gene

Clara Benoit-Pilven, Alicia Besson, Audrey Putoux, Claire Benetollo, Clément Saccaro, Justine Guguin...

PLoS ONE . 15 ( 7 ) : e0235655

DOI: 10.1371/journal.pone.0235655

Journal article

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Studying genetic antagonisms as drivers of genome evolution

Mathieu Joron, Rylan Shearn, Alison E Wright, Sylvain Mousset, Corinne Régis, Simon Penel...

Peer Community In Evolutionary Biology .

DOI: 10.24072/pci.evolbiol.100108

Journal article

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Syndrome de Klinefelter, rôle du chromosome Y dans l’espérance de vie humaine ?

Jordan Teoli, Claire Bardel, Marie Fablet, Gabriel Marais, François Gueyffier, Jean-François Lemaître...

36ème Congrès de la Société Française d'Endocrinologie (SFE Marseille 2020) . 81 ( 4 ) : 194

DOI: 10.1016/j.ando.2020.07.150

Conference paper

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Mindfulness-Based Programs Improve Psychological Flexibility, Mental Health, Well-Being, and Time Management in Academics

Gabriel Marais, Sophie Lantheaume, Robin Fiault, Rebecca Shankland

European Journal of Investigation in Health, Psychology and Education . 10 ( 4 ) : 1035-1050

DOI: 10.3390/ejihpe10040073

Journal article

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Bedrock radioactivity influences the rate and spectrum of mutation

Nathanaëlle Saclier, Patrick Chardon, Florian Malard, Lara Konecny-Dupré, David Eme, Arnaud Bellec...

eLife . 9 : e56830

DOI: 10.7554/eLife.56830

Journal article

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Key role of chromosomal mobile genetic elements transferring by conjugation in the dissemination of antimicrobial resistance in Streptococcus suis

Virginie Libante, Yves Nombre, Charles Coluzzi, Johan Staub, Gérard Guédon, Marcelo Gottschalk...

8th symposium on Antimicrobial Resistance in Animal and Environment .

Conference paper

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The ICE/IME Finder approach and its application to ICE/IME annotation in Streptococcus.

Charles Coluzzi, Julie Lao, Gérard Guédon, Marie-Dominique Devignes, Chloé Ambroset, Thomas Lacroix...

8th symposium on Antimicrobial Resistance in Animal and Environment .

Conference paper

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The ICE/IME Finder approach and its application to ICE/IME annotation in Streptococcus

Charles Coluzzi, Julie Lao, Gérard Guédon, Marie-Dominique Devignes, Chloé Ambroset, Thomas Lacroix...

4th International Workshop on Streptococcus suis .

Poster

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Naturally radioactive environments influence the rate and spectrum of mutation

Nathanaëlle Saclier, Patrick Chardon, Florian Malard, Lara Konecny-Dupré, D. Eme, Arnaud Bellec...

Annual conference of the Society for Molecular Biology and Evolution .

Poster

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Development of a dual RNA-seq strategy to unravel the molecular bases of host-symbiont interactions

Nicolas Parisot, Agnès Vallier, Justin Maire, Mariana G. Ferrarini, Benjamin Gillet, Sandrine Hughes...

Journée scientifique de la FR BioEnviS .

Poster

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High frequency of horizontal transfer in Jockey families (LINE order) of drosophilids

Izabella L Tambones, Annabelle Haudry, Maryanna C Simão, Claudia M A Carareto

Mobile DNA . 10 ( 1 )

DOI: 10.1186/s13100-019-0184-1

Journal article

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Key role of chromosomal mobile genetic elements transferred by conjugation in the dissemination of antimicrobial resistance in S. suis

Virginie Libante, Yves Nombre, Charles Coluzzi, Johan Staub, Gérard Guédon, Marcelo Gottschalk...

4th International Workshop on Streptococcus suis .

Conference paper

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Development of a dual RNA-seq strategy to unravel the molecular bases of host-symbiont interactions

Nicolas Parisot, Agnès Vallier, Justin Maire, Mariana G. Ferrarini, Benjamin Gillet, Sandrine Hughes...

Auvergne Rhône-Alpes Regional Workshop on Microbiome .

Poster

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Archaic mitochondrial DNA inserts in modern day nuclear genomes

Robert Bücking, Murray Cox, Georgi Hudjashov, Lauri Saag, Herawati Sudoyo, Mark Stoneking

BMC Genomics . 20 ( 1 ) : 1017

DOI: 10.1186/s12864-019-6392-8

Journal article

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Contrasting Paternal and Maternal Genetic Histories of Thai and Lao Populations

Wibhu Kutanan, Jatupol Kampuansai, Metawee Srikummool, Andrea Brunelli, Silvia Ghirotto, Leonardo Arias...

Molecular Biology and Evolution . 36 : 1490 - 1506

DOI: 10.1093/molbev/msz083

Journal article

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Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome

Alexander Hübner, Manja Wachsmuth, Roland Schröder, Mingkun Li, Anna Maria Eis-Hübinger, Burkhard Madea...

Scientific Reports . 9 : 11219

DOI: 10.1038/s41598-019-47570-1

Journal article

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The Current Genomic Landscape of Western South America: Andes, Amazonia, and Pacific Coast

Chiara Barbieri, Rodrigo Barquera, Leonardo Arias, José R Sandoval, Oscar Acosta, Camilo Zurita...

Molecular Biology and Evolution . 36 ( 12 ) : 2698 - 2713

DOI: 10.1093/molbev/msz174

Journal article

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WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene

Lilit Nersisyan, Maria Nikoghosyan, Laurent C Francioli, Androniki Menelaou, Sara L Pulit, Clara C Elbers...

Scientific Reports . 9 : 18758

DOI: 10.1038/s41598-019-55109-7

Journal article

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Multiple Deeply Divergent Denisovan Ancestries in Papuans

Guy Jacobs, Georgi Hudjashov, Lauri Saag, Pradiptajati Kusuma, Chelzie Darusallam, Daniel Lawson...

Cell .

DOI: 10.1016/j.cell.2019.02.035

Journal article

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