The “pole biotechnologique” brings together a range of bioengineering expertise for the development of tools and approaches for research in evolutionary biology; and operational competences to ensure their logistical and technical implementation.
Since it was set up, the biotechnology hub has perpetuated insect breeding activities, including several species of drosophila, but also Venturia and Bemisia for example. These breeding activities are carried out on artificial medium or plants. We ensure laboratory logistics (e.g. autoclave, stock management, ...) as well as safety aspects, and develop devices (e.g. via 3D printing) to feed experimental research in the laboratory focusing on evolutionary genomics, behavioural ecology and functional ecology.
Our expertise is also solicited to organize field work, in metropolitan France and internationally, and to carry out population monitoring of terrestrial mammals (e.g. roe deer, marmots, feral cats, bats) and birds (dipper). In addition to capture (e.g. trapping, netting), marking and monitoring of animals, we implement experimental approaches in natura, collect biometric, behavioral and physiological data, biological samples (blood, secretions, hair, faeces, biopsy, ...) and characterize the study environments (installation of sensors, aerial imaging by drones, construction of digital models of terrain ...).
Finally, the biotechnology hub offers the technical resources and skills to analyse a wide variety of biological samples in the laboratory through an multidisciplinary prism. The complementarity and synergy of our competences are expressed in the fields of molecular biology (PCR, qPCR, construction of libraries for the genesis of ohmic data), cell biology (confocal microscopy, flow cytometry), and biochemistry (characterization of metabolic, endocrine and oxidative profiles).
Rehabilitation work is currently underway at the LBBE and will lead to a significant expansion of the experimental space. These new premises will allow us to increase our capacity, to offer new spaces and modern tools dedicated to behavioral approaches. These new premises will also allow us to widen the spectrum of our activities by developing new techniques (e.g. cell culture, Crispr/cas9, RNAi, ...).
In all our activities, we regularly welcome and supervise trainees and students of all levels. For any questions or information request, do not hesitate to contact us.
Display of 1 to 30 publications on 158 in total
Detection and monitoring of Drosophila suzukii in raspberry and cherry orchards with volatile organic compounds in the USA and Europe
Scientific Reports . 11 ( 1 )
Short-term telomere dynamics is associated with glucocorticoid levels in wild populations of roe deer
Comparative Biochemistry and Physiology - A: Comparative Physiology . 252 : 1-7
Drosophila suzukii oxidative stress response involves Jheh gene cluster but not transposable elements
No sex differences in adult telomere length across vertebrates: a meta-analysis
Royal Society Open Science . 7
How consistent is RAD‐seq divergence with DNA‐barcode based clustering in insects?
Molecular Ecology Resources . 20 ( 5 ) : 1294-1298
Experimental evolution of virulence and associated traits in a Drosophila melanogaster - Wolbachia symbiosis
Peer Community in Evolutionary Biology .
Under cover of the night: context-dependency of anthropogenic disturbance on stress levels of wild roe deer Capreolus capreolus
Conservation Physiology . 8 ( 1 )
An efficient RNA-seq-based segregation analysis identifies the sex chromosomes of Cannabis sativa
Genome Research . 30 ( 2 ) : 164-172
Validation of the predation-stress hypothesis in a large mammal
Functional Ecology .
Increased Diurnal Activity Is Indicative of Energy Deficit in a Nocturnal Mammal, the Aardvark
Frontiers in Physiology . 11 : 637
A transposon story : from TE content to TE dynamic invasion of Drosophila genomes using the single-molecule sequencing technology from Oxford Nanopore
A behavior-manipulating virus relative as a source of adaptive genes for Drosophila parasitoids
Molecular Biology and Evolution . 37 ( 10 ) : 2791-2807
Phenotypic plasticity in the invasive pest Drosophila suzukii: activity rhythms and gene expression in response to temperature
Journal of Experimental Biology . 222 : jeb199398
Evolution of Hepatitis B Virus Receptor NTCP Reveals Differential Pathogenicities and Species Specificities of Hepadnaviruses in Primates, Rodents, and Bats
Journal of Virology . 93 ( 5 )
The neutrophil to lymphocyte ratio indexes individual variation in the behavioural stress response of wild roe deer across fluctuating environmental conditions
Behavioral Ecology and Sociobiology . 73 ( 11 ) : 1-13
Dynamic Interactions Between the Genome and an Endogenous Retrovirus: Tirant in Drosophila simulans Wild-Type Strains
G3 . 9 ( 3 ) : 855-865
A behavior-manipulating virus relative as a source of adaptive genes for parasitoid wasps
Development of a PCR-RFLP assay to identify Drosophila melanogaster among field-collected larvae
Ecology and Evolution . 8 ( 20 ) : 10067 - 10074
The ground plot counting method: A valid and reliable assessment tool for quantifying seed production in temperate oak forests?
Forest Ecology and Management . 430 : 143-149
Coexistence of two sympatric cryptic bat species in French Guiana: insights from genetic, acoustic and ecological data
BMC Evolutionary Biology . 18 ( 1 )
Coexistence de deux espèces cryptiques de chauves-souris en Guyane française : apprentissages à partir de la génétique de l’acoustique et de l’écologie
Plume de Naturalistes . 2 : 169-190
Time course of liver mitochondrial function and intrinsic changes in oxidative phosphorylation in a rat model of sepsis
INTENSIVE CARE MEDICINE EXPERIMENTAL . 6 ( 31 ) : 1-17
Females pay the oxidative cost of dominance in a highly social bird.
Animal Behaviour . 144 : 135-146
The influence of early‐life allocation to antlers on male performance during adulthood: Evidence from contrasted populations of a large herbivore
Journal of Animal Ecology . 87 ( 4 ) : 921-932
Stress levels of dominants reflect underlying conflicts with subordinates in a cooperatively breeding species.
Behavioral Ecology and Sociobiology . 72 ( 4 ) : 72
An attempt to select non-genetic variation in resistance to starvation and reduced chill coma recovery time in Drosophila melanogaster
Journal of Experimental Biology . 221 ( 23 ) : jeb186254
Abundance of Bemisia tabaci Gennadius (Hemiptera: Aleyrodidae) and its parasitoids on vegetables and cassava plants in Burkina Faso (West Africa)
Ecology and Evolution . 8 ( 12 ) : 6091-6103
Deciphering the behaviour manipulation imposed by a virus on its parasitoid host: insights from a dual transcriptomic approach
Identification of misexpressed genetic elements in hybrids between Drosophila-related species
Scientific Reports . 7 : 40618
Complication-related removal of totally implantable venous access port systems: Does the interval between placement and first use and the neutropenia-inducing potential of chemotherapy regimens influence their incidence? A four-year prospective study of 4
EJSO - European Journal of Surgical Oncology . 43 ( 4 ) : 689-695