COEVOL Multi-Scale Coevolution
Living systems are highly integrated, with a multitude of levels of organization, from molecular and intra-cellular scales to ecosystems. Complex organisms are themselves consortia of macro- and micro-organisms, which work together with their host to build the individual. Yet, each of these organisms can function and evolve in the short term according to its own logic, possibly in conflict with other higher or lower levels, or with other time scales. The once common idea among evolutionists that natural selection results in organisms perfectly adapted to their environment is now severely undermined. Not only because, as the Red Queen explains to Alice, one has to run relentlessly to keep its place in a changing environment, or because past evolutionary history and chance constrain the possibilities of present adaptation, but also because different levels of selection have interests that are generally difficult to reconcile.
Multi-scale coevolution resets classical questions in evolutionary biology
One example, of particular interest is the question of the source of heritable variations. The phenotype of organisms in a population is influenced not only by variations in their nuclear and mitochondrial genomes, the dynamics of which is the object of population genetics, but also more and more patently by the consortium of microbes and genetic elements that constitute its microbiome and virome. The hologenome designates this complex assembly of genetic materials, which obey different rules of transmission and different evolutionary strategies. The ability of symbionts to manipulate host phenotypes or to interfere with each other influences the evolutionary dynamics of all players in ways that are yet poorly understood. In addition, new questions arise, such as the importance of co-adaptation in these systems and their consequences in maintaining cohesive biological systems.
- Symbiosis: a response to and a source of divergent selection
Using a variety of approaches combining experimental evolution, genomic, functional, phenotypic and behavioral data, we aim to test whether symbiosis facilitates diversification and to characterize the underlying microevolutionary processes.
- Ecological networks of horizontal gene transfer
We develop original methods to detect gene transfer and we investigate the factors that influence the routes of gene transfers among microbes but also among insects.
- The interplay between symbiosis, infection and immunity and its evolutionary consequences
We try to understand the intimate interaction of hosts with pathogens, symbionts and transposable elements and how it affects the extended phenotype of the host.
- Transgenerational inheritance and environment changes
We try to decipher the molecular mechanisms that underlie rapid adaptation to environment and to test for transgenerational inheritance of fitness traits.
- Intragenomic conflicts and demography
We are developing models to test whether changes in the demography of the host affect the dynamics of transposable elements.
- The determinism of phenotypic convergence
We study the genomic basis of convergent phenotypic evolution in particular in the case of animals and plants adaptation to increasing temperature and decreasing water.
- Reconciling the tree of life
We develop phylogenetic methods for “reconciling” gene/species or host/symbiont histories and use these methods to explore the bulk of extinct or undescribed species and the history of association of symbiotic microbes with their hosts.
Integrating methods
The methods we use to tackle the questions raised by multi-scale co-evolution extend from theory, modelling and simulation to big data analysis, lab (notably on insects), and to a lesser extent, field activities.
Implication of research, responsibility of researchers and citizen sciences
From our research (some of which have immediate consequences in health, agriculture and ecology) and our concerns about the responsibility of scientists in society, we are committed to promote an “implicative” research. The implicative position means that we try to work on the link between science and society, not only through a one-way communication, applying or explaining our science, but also favoring early discussions on research projects, that may influence our research directions.
Publications
Display of 1 to 30 publications on 703 in total
Dating the origin of a viral domestication event in parasitoid wasps attacking Diptera
Preprint
see the publicationTranscriptomic Response to Pyrethroid Treatment in Closely Related Bed Bug Strains Varying in Resistance
Genome Biology and Evolution . 16 ( 8 ) : evae158
DOI: 10.1093/gbe/evae158
Journal article
see the publicationEpigenetics and genotypic variation
On Epigenetics and Evolution . : 119-151
Book chapter
see the publicationEffects of Arboviral Infections on Transposable Element Transcript Levels in Aedes aegypti
Genome Biology and Evolution . 16 ( 5 ) : evae092
DOI: 10.1093/gbe/evae092
Journal article
see the publicationHuman-aided dispersal and population bottlenecks facilitate parasitism escape in the most invasive mosquito species
PNAS Nexus . 3 ( 5 ) : 175
Journal article
see the publicationA novel and diverse family of filamentous DNA viruses associated with parasitic wasps
Virus Evolution . 10 ( 1 ) : veae022
DOI: 10.1093/ve/veae022
Journal article
see the publicationDevelopment, feeding, and sex shape the relative quantity of the nutritional obligatory symbiont Wolbachia in bed bugs
Frontiers in Microbiology . 15 : 1386458
Journal article
see the publicationCommunity structure of heritable viruses in a Drosophila-parasitoids complex
Peer Community Journal . 4 : e16
Journal article
see the publicationResponse to “On the impact of incomplete taxon sampling on the relative timing of gene transfer events”
PLoS Biology . 22 ( 3 ) : e3002557
Journal article
see the publicationThe for gene as one of the drivers of foraging variations in a parasitic wasp
Molecular Ecology . 32 ( 7 ) : 1760-1776
DOI: 10.1111/mec.16834
Journal article
see the publicationPlant choice for oviposition in the phytophagous insect Bemisia tabaci: cytotype, including symbionts, knows best!
Animal Behaviour . 200 : 147-157
Journal article
see the publicationStudy of host-symbionts coevolution in the whitefly Bemisia tabaci: an experimental evolution approach
13e Rencontre du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA) .
Conference paper
see the publicationSecondary symbionts influence feeding and oviposition behavior in the whitefly Bemisia tabaci
XII European Congress of Entomology .
Poster
see the publicationThe for gene as one of the drivers of foraging variations in a parasitic wasp
Molecular Ecology . 32 ( 7 ) : 1760-1776
DOI: 10.1111/mec.16834
Journal article
see the publicationA comprehensive evolutionary scenario for the origin and neofunctionalization of the Drosophila speciation gene Odysseus (OdsH)
G3 . 14 ( 3 ) : jkad299
Journal article
see the publicationAn evolutionary timescale for Bacteria calibrated using the Great Oxidation Event
Preprint
see the publicationEvaluation of Methods to Detect Shifts in Directional Selection at the Genome Scale
Molecular Biology and Evolution . 40 ( 2 )
Journal article
see the publicationApproche globale des éthiques dans les relations sociétés/nature
: 211-219
Report
see the publicationA major 6 Mb superlocus is involved in pyrethroid resistance in the common bed bug Cimex lectularius
Evolutionary Applications . 16 ( 5 ) : 1012 - 1028
DOI: 10.1111/eva.13550
Journal article
see the publicationNutritional symbioses in triatomines: who is playing?
Peer Community In Evolutionary Biology . : 100629
Journal article
see the publicationIdentification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues
Preprint
see the publicationImpact of Heat Stress on Transposable Element Expression and Derived Small RNAs in Drosophila subobscura
Genome Biology and Evolution . 15 ( 11 ) : evad189
DOI: 10.1093/gbe/evad189
Journal article
see the publicationDual control of host actin polymerization by a Legionella effector pair
Preprint
see the publicationA quantitative, genome-wide analysis in Drosophila reveals transposable elements’ influence on gene expression is species-specific
Genome Biology and Evolution . 15 ( 9 ) : evad160
DOI: 10.1093/gbe/evad160
Journal article
see the publicationChimeraTE: a pipeline to detect chimeric transcripts derived from genes and transposable elements
Nucleic Acids Research . 51 ( 18 ) : 9764-9784
DOI: 10.1093/nar/gkad671
Journal article
see the publicationPlant choice for oviposition in the phytophagous insect Bemisia tabaci: cytotype, including symbionts, knows best!
Animal Behaviour . 200 : 147-157
Journal article
see the publicationEndoparasitoid lifestyle promotes endogenization and domestication of dsDNA viruses
eLife . 12 : e85993
DOI: 10.7554/eLife.85993
Journal article
see the publicationBack to the trees: Identifying plants with Human Intelligence
LIMITS 2023 - Ninth Workshop on Computing within Limits . : 1-11