Evolutionary Genetics of Interactions Group

Members

Living systems are made up of a multitude of interlocking levels of organization, involving cooperation and conflict. Cooperation and the selection of systems operating in a coordinated manner has allowed so-called "major" evolutionary transitions, towards new scales of individuality, such as the eukaryotic cell. Nevertheless, natural selection continues to operate at all scales, generating possible evolutionary conflicts between the different components of the individual.

Our research is in line with this perspective, and aims to better understand the nature and evolutionary implications of the interactions between the multiple components of organisms, from genes to symbiotic bacteria, viruses and transposable elements. We also explore the impact of these interactions on the dynamics of genetic information, through horizontal transfer, or on genetic innovation and adaptation, through domestication. Our research, mainly experimental, but also theoretical, is implemented on arthropod models, and is mainly related to genetics and evolutionary genomics.

The team is structured along two main axis:

  •     Intragenomic interactions: transposable elements (resp. Marie Fablet)

        Ex1: The evolutionary dynamics of transposable elements (TEs) in genomes, in relation to their natural variability.      Our models include natural populations of Drosophila melanogaster and D. simulans, as well as species of agronomic or societal interest, such as the invasive species D. suzukii or the tiger mosquito Aedes albopictus.
        Ex2: Interactions between ET control and anti-viral immunity. We are studying the molecular mechanisms of RNA interference at the origin of the entanglement of these two processes, as well as the co-evolutionary implications, using experimental infections of different viruses on several Drosophila lines.
        People involved : CV, MB, MF

  •     Symbiosis, the driving force of evolution (resp. Natacha Kremer)

        Ex1 : Certain symbiotic bacteria provide metabolic capacities that the insect lacks. We are analysing these interactions in haematophagous insects (bedbugs, ticks) and phytophagous insects (the whitefly Bemisia tabaci) using approaches combining phenotype analysis, genetics, physiology and metabolomics.
        Ex2: Parasitoid insects have domesticated viral genes enabling them to bypass the immune responses of their hosts. We are studying the frequency and adaptive significance of these events and, more generally, looking into the factors structuring horizontal transfers in host-parasitoid communities.
        People involved: NK, LM, LZ, JMD, JV, FV, SC

 

Publications

Display of 1 to 30 publications on 462 in total

Transposable elements as evolutionary driving force to host shift in cactophilic Drosophila species

D. Oliveira, A. Larue, W. Nunes, F. Sabot, A. Bodelón, M. García Guerreiro...

DOI: 10.1101/2024.03.27.587021

Preprint

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Exploring the role of transposable elements to sex gap in longevity in Drosophila species

Miriam Merenciano, Sonia Janillon, Camille Mermet-Bouvier, Nelly Burlet, Valentina Rodriguez-Rada, Victor Ronget...

DOI: 10.1101/2025.01.22.634250

Preprint

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Dating the origin of a viral domestication event in parasitoid wasps attacking Diptera

Benjamin Guinet, Jonathan Vogel, Nabila Kacem Haddj El Mrabet, Ralph S Peters, Jan Hrcek, Mattew L Buffington...

Proceedings of the Royal Society B: Biological Sciences . 292 ( 2039 )

DOI: 10.1098/rspb.2024.2135

Journal article

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Phylogenetic relatedness rather than aquatic habitat fosters horizontal transfer of transposable elements in animals

Héloïse Muller, Rosina Savisaar, Jean Peccoud, Sylvain Charlat, Clément Gilbert

DOI: 10.1101/2024.12.18.629015

Preprint

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Epigénétique et Eléments Transposables

Clémentine Vitte, Séverine Chambeyron, Cristina Vieira

Epigénétique en écologie et évolution . 978-1-78948-216-4 : 95-116

Book chapter

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Contribution of variable TE content on phenotype and plasticity in Drosophila melanogaster.

Anaïs Larue, Miriam Merenciano, S. Janillon, Marie Fablet, Patricia Gibert, Abdelaziz Heddi...

Annual meeting of the Society of Molecular Biology and Evolution (SMBE) .

Conference paper

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Contribution of variable TE content on phenotype and plasticity in Drosophila melanogaster.

Anaïs Larue, Miriam Merenciano, S. Janillon, Marie Fablet, Patricia Gibert, Abdelaziz Heddi...

Conférence Jacques Monod Life is plastic .

Conference paper

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Functional analysis of interactions between bed bugs and their symbionts Wolbachia and BEV-like

Raphaël Jorge, Marius Poulain, Elodie Rosinski, Hélène Henri, Adil El Filali, Patrice Baa-Puyoulet...

International congress of Ecology and Evolution (SFE2) .

Conference paper

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Intricate interactions between antiviral immunity and transposable element control in Drosophila

Camille A Mayeux, Anaïs Larue, Daniel S Oliveira, Marion Varoqui, Hélène Henri, Rita Rebollo...

DOI: 10.1101/2024.03.18.585529

Preprint

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Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues

Rita Rebollo, Pierre Gerenton, Eric Cumunel, Arnaud Mary, François Sabot, Nelly Burlet...

DOI: 10.1101/2023.05.27.542554

Preprint

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Efficient compartmentalization in insect bacteriomes protects symbiotic bacteria from host immune system

Mariana Galvão Ferrarini, Elisa Dell’aglio, Agnès Vallier, Séverine Balmand, Carole Vincent-Monégat, Sandrine Hughes...

DOI: 10.1101/2022.03.18.484386

Preprint

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Contribution of variable TE content on phenotype and plasticity in Drosophila melanogaster

Anaïs Larue, Miriam Merenciano, S. Janillon, Agnès Vallier, Marie Fablet, Patricia Gibert...

International congress of transposable elements .

Poster

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Contribution of TE to the phenotype and plasticity in Drosophila melanogaster

Anaïs Larue, Miriam Merenciano, S. Janillon, Camille Mayeux, Marie Fablet, Séverine Chambeyron...

27th European Drosophila Conference .

Poster

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Footprints of worldwide adaptation in structured populations of D. melanogaster through the expanded DEST 2.0 genomic resource

Joaquin C. B. Nunez, Marta Coronado-Zamora, Mathieu Gautier, Martin Kapun, Sonja Steindl, Lino Ometto...

DOI: 10.1101/2024.11.10.622744

Preprint

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Efficient compartmentalization in insect bacteriomes protects symbiotic bacteria from host immune system

Carole Vincent-Monégat, Mariana G. Ferrarini, Elisa Dell’aglio, Agnès Vallier, Severine Balmand, Sandrine Hugues...

8th International Symposium on Antimicrobial Peptides .

Poster

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Insect population dynamics under Wolbachia-induced cytoplasmic incompatibility: Puzzle more than buzz in Drosophila suzukii

Alexandra Auguste, N. Ris, Zainab Belgaidi, Laurent Kremmer, Laurence Mouton, Xavier Fauvergue

PLoS ONE . 19 ( 3 ) : e0300248

DOI: 10.1371/journal.pone.0300248

Journal article

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The transposable element-rich genome of the cereal pest Sitophilus oryzae

Nicolas Parisot, Carlos Vargas-Chavez, Clément Goubert, Patrice Baa-Puyoulet, Séverine Balmand, Louis Beranger...

DOI: 10.1101/2021.03.03.408021

Preprint

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Transcriptomic Response to Pyrethroid Treatment in Closely Related Bed Bug Strains Varying in Resistance

Chloé Haberkorn, Zaïnab Belgaïdi, Romain Lasseur, Fabrice Vavre, Julien Varaldi

Genome Biology and Evolution . 16 ( 8 ) : evae158

DOI: 10.1093/gbe/evae158

Journal article

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Insect population dynamics under Wolbachia-induced cytoplasmic incompatibility: puzzle more than buzz in Drosophila suzukii

Alexandra Auguste, Nicolas Ris, Zainab Belgaidi, Laurent Kremmer, Laurence Mouton, Xavier Fauvergue

DOI: 10.1101/2023.08.02.551598

Preprint

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Effects of Arboviral Infections on Transposable Element Transcript Levels in Aedes aegypti

Chloé Garambois, Matthieu Boulesteix, Marie Fablet

Genome Biology and Evolution . 16 ( 5 ) : evae092

DOI: 10.1093/gbe/evae092

Journal article

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Human-aided dispersal and population bottlenecks facilitate parasitism escape in the most invasive mosquito species

Maxime Girard, Edwige Martin, Laurent Vallon, Van Tran Van, Camille da Silva Carvalho, Justine Sack...

PNAS Nexus . 3 ( 5 ) : 175

DOI: 10.1093/pnasnexus/pgae175

Journal article

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A novel and diverse family of filamentous DNA viruses associated with parasitic wasps

Benjamin Guinet, Matthieu Leobold, Elisabeth Herniou, Pierrick Bloin, Nelly Burlet, Justin Bredlau...

Virus Evolution . 10 ( 1 ) : veae022

DOI: 10.1093/ve/veae022

Journal article

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Development, feeding, and sex shape the relative quantity of the nutritional obligatory symbiont Wolbachia in bed bugs

Marius Poulain, Elodie Rosinski, Hélène Henri, Séverine Balmand, Marie Laure Delignette-Muller, Abdelaziz Heddi...

Frontiers in Microbiology . 15 : 1386458

DOI: 10.3389/fmicb.2024.1386458

Journal article

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Community structure of heritable viruses in a Drosophila-parasitoids complex

Julien Varaldi, David Lepetit, Nelly Burlet, Camille Faber, Bérénice Baretje, Roland Allemand

Peer Community Journal . 4 : e16

DOI: 10.24072/pcjournal.371

Journal article

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Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues

Rita Rebollo, Pierre Gerenton, Eric Cumunel, Arnaud Mary, François Sabot, Nelly Burlet...

Peer Community Journal . 4 ( e89 )

DOI: 10.24072/pcjournal.457

Journal article

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Transposable element expression with variation in sex chromosome number: insights into a toxic Y effect on human longevity

Jordan Teoli, Miriam Merenciano, Marie Fablet, Anamaria Necsulea, Daniel Siqueira-De-Oliveira, Alessandro Brandulas-Cammarata...

Peer Community In Genomics .

DOI: 10.1101/2023.08.03.550779

Journal article

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Étude des interactions entre la punaise de lit et son symbiote nutritionnel obligatoire, Wolbachia.

Marius Poulain, Elodie Rosinski, Hélène Henri, Severine Balmand, Abdelaziz Heddi, Romain Lasseur...

Rencontres du Groupe Régional de Recherche en Microbiologie des Interactions (G-RREMI) 2023 .

Conference paper

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Feeding, sex, and development shape the relative quantity of Wolbachia, the nutritional obligatory symbiont of bed bugs

Marius Poulain, Elodie Rosinski, Hélène Henri, Severine Balmand, Abdelaziz Heddi, Romain Lasseur...

Rencontres du Réseau Ecologie des Interactions Durables 2023 .

Poster

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