COEVOL Multi-Scale Coevolution

Evolutionary Genetics of Interactions Group

Boulesteix Matthieu

Maître de conférences

UCBL

Address: 43 bd du 11 novembre 1918
69622 VILLEURBANNE cedex

Tel: 04 72 43 29 16

Email

Research interests

Transposable elements (TEs) are repeated sequences of DNA that populate the genome of every single species and are able to replicate and insert new copies of themselves into the genome they inhabit. As they are devoid of any obvious function for their host organism and induce mutations that are most of the time deleterious, TEs are often seen as genomic parasites.

The goal of my research is to understand the factors that determine the proliferation of these parasites and the ins and outs of the cohabitation between genes and TEs within genomes.

Current projects

Invasive species: TEs dynamics and contribution to adaptation

Invasive species constitute an ideal model to study real-time evolution. With regard to TEs they provide a way to understand how demographic factors (range expansions accompanied by founder effects) can influence TEs dynamics. In addition while TEs are deleterious in general several spectacular examples of TE-based adaptations have been described. Invasive species can thus be used to study the contribution of TEs to the adaptation of populations to new environments. We have been able to show in Drosophila suzukii, an invasive species in Europe and the United States, that the invasive process was associated with an increase of the genomes' TE load, which seems to be linked to bottlenecks that accompany the invasion (Mérel et al. 2021). We also work with the Asian tiger mosquito Aedes albopictus, an invasive species from Asia, and described its repeatome (Goubert et al. 2015). We showed that in this species several insertions segregate at high frequencies in Europe which suggests that they might be involved in the adaptation of this mosquito to temperate environments (Goubert et al. 2017). We are currently extending this study through the comparison of numerous complete genomes from native and invasive populations of this species (ANR funded project MosquiTEs, PI M Boulesteix) to get a better understanding of the contribution of TEs in the adaptive process.

Interactions between viral infections and transposition rates

Natural selection has enabled the emergence of defense systems in genomes allowing them to protect themselves against the deleterious effects of TEs. In many organisms small RNAs (piRNAs and siRNAs) are central to these defense system. Defense against viruses is also ensured thanks to small RNAs (siRNAs in Drosophila, piRNAs and siRNAs in mosquitoes). It is thus tempting to ask whether viral infections could interfere with TEs control and conversely. This question is currently addressed by Chloé Garambois during her PhD (supervision: Marie Fablet and Matthieu Boulesteix).

Publications

Display of 1 to 23 publications on 23 in total

The Worldwide Invasion of Drosophila suzukii Is Accompanied by a Large Increase of Transposable Element Load and a Small Number of Putatively Adaptive Insertions

Vincent Mérel, Patricia Gibert, Inessa Buch, Valentina Rodriguez Rada, Arnaud Estoup, Mathieu Gautier...

Molecular Biology and Evolution . 38 ( 10 ) : 4252-4267

DOI: 10.1093/molbev/msab155

Journal article

see the publication

The genome of the cereal pest Sitophilus oryzae : a transposable element haven

Nicolas Parisot, Carlos Vargas-Chavez, Clément Goubert, Patrice Baa-Puyoulet, Severine Balmand, Louis Beranger...

DOI: 10.1101/2021.03.03.408021

Preprint

see the publication

A transposon story : from TE content to TE dynamic invasion of Drosophila genomes using the single-molecule sequencing technology from Oxford Nanopore

Mohamed Mourdas, Nguyet Thi-Minh Dang, Yuki Ogyama, Nelly Burlet, Bruno Mugat, Matthieu Boulesteix...

Cells . 9 ( 8 ) : 1776

DOI: 10.3390/cells9081776

Journal article

see the publication

A behavior-manipulating virus relative as a source of adaptive genes for Drosophila parasitoids

D Di Giovanni, D. Lepetit, B Guinet, B Bennetot, M. Boulesteix, Yohann Couté...

Molecular Biology and Evolution . 37 ( 10 ) : 2791-2807

DOI: 10.1093/molbev/msaa030

Journal article

see the publication

Transposable Element Dynamics in an Invasive Species

V. Mérel, Marie Fablet, M. Boulesteix, Arnaud A Estoup, Patricia Gibert, Cristina Vieira

Congrès National des Éléments Transposables (CNET 2018) .

Conference paper

see the publication

Evaluating the essentiality of the primary endosymbiont of the rice weevil Sitophilus oryzae through genome analysis

Carlos Vargas-Chavez, Nicolas Parisot, C. Goubert, Patrice Baa-Puyoulet, Severine Balmand, M. Boulesteix...

VI Meeting of the Spanish Society for Evolutionary Biology (SESBE) .

Poster

see the publication

A behavior-manipulating virus relative as a source of adaptive genes for parasitoid wasps

Deborah Di Giovanni, D. Lepetit, Matthieu Boulesteix, Marc Ravallec, Julien Varaldi

Preprint

see the publication

High-Throughput Sequencing of Transposable Element Insertions Suggests Adaptive Evolution of the Invasive Asian Tiger Mosquito Towards Temperate Environments

Clément Goubert, Hélène Henri, Guillaume Minard, Claire Valiente Moro, Patrick Mavingui, Cristina Vieira...

Molecular Ecology . 26 ( 15 ) : 1-14

DOI: 10.1111/mec.14184

Journal article

see the publication

Population genetics of the Asian tiger mosquito Aedes albopictus, an invasive vector of human diseases

C. Goubert, G. Minard, Cristina Vieira, Matthieu Boulesteix

Heredity . 117 ( 3 ) : 125-34

DOI: 10.1038/hdy.2016.35

Journal article

see the publication

The draft genome sequence of the rice weevil Sitophilus oryzae as a model to explore the host-symbiont interactions in a nascent stage of endosymbiosis

Carlos Vargas-Chavez, Nicolas Parisot, Clément Goubert, Patrice Baa-Puyoulet, Severine Balmand, M. Boulesteix...

Journées Ouvertes Biologie Informatique Mathématiques (JOBIM) .

Poster

see the publication

De novo assembly and annotation of the Asian tiger mosquito (Aedes albopictus) repeatome with dnaPipeTE from raw genomic reads and comparative analysis with the yellow fever mosquito (Aedes aegypti).

Clément Goubert, Laurent Modolo, Cristina Vieira, Claire Valientemoro, Patrick Mavingui, Matthieu Boulesteix

Genome Biology and Evolution . 7 ( 4 ) : 1192-205

Journal article

see the publication

De novo assembly and annotation of the Asian tiger mosquito (Aedes albopictus) repeatome with dnaPipeTE from raw genomic reads and comparative analysis with the yellow fever mosquito (Aedes aegypti)

Clément Goubert, Laurent Modolo, Cristina Vieira, Claire Valiente Moro, Patrick Mavingui, Matthieu Boulesteix

Genome Biology and Evolution . 7 ( 4 ) : 1192-1205

DOI: 10.1093/gbe/evv050

Journal article

see the publication

A comparative analysis of the amounts and dynamics of transposable elements in natural populations of Drosophila melanogaster and Drosophila simulans.

Cristina Vieira, Marie Fablet, Emmanuelle Lerat, Matthieu Boulesteix, Rita Rebollo, Nelly Burlet...

Journal of Environmental Radioactivity . 113 : 83-86

DOI: 10.1016/j.jenvrad.2012.04.001

Journal article

see the publication

Isolation and gene flow: inferring the speciation history of European house mice

Ludovic Duvaux, Khalid Belkhir, Matthieu Boulesteix, Pierre Boursot

Molecular Ecology . 20 ( 24 ) : 5248-5264

DOI: 10.1111/j.1365-294X.2011.05343.x

Journal article

see the publication

Isolation and gene flow: inferring the speciation history of European house mice

Ludovic Duvaux, K. Belkhir, Matthieu Boulesteix, P. Boursot

Molecular ecology . 20 : 5248-5264

DOI: 10.1111/j.1365-294X.2011.05343.x

Journal article

see the publication

How sympatric is speciation in the Howea palms of Lord Howe Island ?

W. Babik, R.K. Butlin, W. Baker, A.S.T. Papadopulos, Matthieu Boulesteix, M.C. Anstett...

Molecular Ecology . 18 : 3629-3638

Journal article

see the publication

High Genetic Differentiation between the M and S Molecular Forms of Anopheles gambiae in Africa

C. Esnault, M. Boulesteix, J.B. Duchemin, A.A. Koffi, F. Chandre, R. Dabiré...

PLoS ONE . 3 : 1-7

Journal article

see the publication

Insertion polymorphism of transposable elements and population structure of Anopheles gambiae M and S molecular forms in Cameroon

M. Boulesteix, F. Simard, C. Antonio-Nkondjio, P. Awono-Ambene, D. Fontenille, C. Biémont

Molecular Ecology . 16 : 441-452

Journal article

see the publication

Differences in genome size between closely related species: the Drosophila melanogaster species subgroup.

Matthieu Boulesteix, Michèle Weiss, Christian Biémont

Molecular Biology and Evolution . 23 ( 1 ) : 162-7

DOI: 10.1093/molbev/msj012

Journal article

see the publication

Differences in Genome Size Between Closely Related Species : The Drosophila melanogaster Species Subgroup

M. Boulesteix, M. Weiss, C. Biémont

Molecular Biology and Evolution . 23 : 162-167

Journal article

see the publication

Differences in genom size between closely related species : the drosophila melanogaster species subgroup.

M. Boulesteix, M. Weiss, C. Biemont

Molecular Biology and Evolution . ( 23 ) : 162-167

Journal article

see the publication

Transposable elements in mosquitoes

Matthieu Boulesteix, Christian Biémont

Cytogenetics and Genome Research . 110 : 500--509

Journal article

see the publication