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Showing results 41 to 60 on 6835 in total
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Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Serena Nik-Zainal, Helen R. Davies, Johan Staaf, Manasa Ramakrishna, Dominik Glodzik, Xueqing Zou, Inigo Martincorena, Ludmil B. Alexandrov, Sancha Martin, David C. Wedge, Peter van Loo, Young Seok Ju, Marcel Smid, Arie B. Brinkman, Sandro Morganella, Miriam R. Aure, Ole Christian Lingjærde, Anita Langerød, Markus Ringnér, Sung-Min Ahn, Sandrine Boyault, Jane E. Brock, Anne Broeks, Adam Butler, Christine Desmedt, Luc Dirix, Serge Dronov, Aquila Fatima, John A. Foekens, Moritz Gerstung, Gerrit K. J. Hooijer, Se Jin Jang, David R. Jones, Hyung-Yong Kim, Tari A. King, Savitri Krishnamurthy, Hee Jin Lee, Jeong-Yeon Lee, Yilong Li, Stuart Mclaren, Andrew Menzies, Ville Mustonen, Sarah O’meara, Iris Pauporté, Xavier Pivot, Colin A. Purdie, Keiran Raine, Kamna Ramakrishnan, F. Germán Rodríguez-González, Gilles Romieu, Anieta M. Sieuwerts, Peter Simpson, Rebecca Shepherd, Lucy Stebbings, Olafur A. Stefansson, Jon Teague, Stefania Tommasi, Isabelle Treilleux, Gert G. van den Eynden, Peter Vermeulen, Anne Vincent-Salomon, Lucy Yates, Carlos Caldas, Laura Van’t Veer, Andrew Tutt, Stian Knappskog, Benita Kiat Tee Tan, Jos Jonkers, Åke Borg, Naoto T. Ueno, Christos Sotiriou, Alain Viari, P. Andrew Futreal, Peter J. Campbell, Paul N. Span, Steven van Laere, Sunil R. Lakhani, Jorunn E. Eyfjord, Alastair M. Thompson, Ewan Birney, Hendrik G. Stunnenberg, Marc J. van de Vijver, John W. M. Martens, Anne-Lise Børresen-Dale, Andrea L. Richardson, Gu Kong, Gilles Thomas, Michael R. Stratton
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HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
Helen Davies, Dominik Glodzik, Sandro Morganella, Lucy R Yates, Johan Staaf, Xueqing Zou, Manasa Ramakrishna, Sancha Martin, Sandrine Boyault, Anieta M Sieuwerts, Peter T Simpson, Tari A King, Keiran Raine, Jorunn E Eyfjord, Gu Kong, Åke Borg, Ewan Birney, Hendrik G Stunnenberg, Marc J van de Vijver, Anne Børresen-Dale, John W M Martens, Paul N Span, Sunil R Lakhani, Anne Vincent-Salomon, Christos Sotiriou, Andrew Tutt, Alastair M Thompson, Steven van Laere, Andrea L Richardson, Alain Viari, Peter J Campbell, Michael R Stratton, Serena Nik-Zainal
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Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency
Helen Davies, Sandro Morganella, Colin A. Purdie, Se Jin Jang, Elin Borgen, Hege Russnes, Dominik Glodzik, Xueqing Zou, Alain Viari, Andrea L. Richardson, Anne-Lise Børresen-Dale, Alastair Thompson, Jorunn E. Eyfjord, Gu Kong, Michael R. Stratton, Serena Nik-Zainal
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Somatic mutations reveal asymmetric cellular dynamics in the early human embryo
Young Seok Ju, Inigo Martincorena, Moritz Gerstung, Mia Petljak, Ludmil B. Alexandrov, Raheleh Rahbari, David C. Wedge, Helen R. Davies, Manasa Ramakrishna, Anthony Fullam, Sancha Martin, Christopher Alder, Nikita Patel, Steve Gamble, Sarah O’meara, Dilip D. Giri, Torril Sauer, Sarah E. Pinder, Colin A. Purdie, Åke Borg, Henk Stunnenberg, Marc van de Vijver, Benita K. T. Tan, Carlos Caldas, Andrew Tutt, Naoto T. Ueno, Laura J. van ’t Veer, John W. M. Martens, Christos Sotiriou, Stian Knappskog, Paul N. Span, Sunil R. Lakhani, Jórunn Erla Eyfjörd, Anne-Lise Børresen-Dale, Andrea Richardson, Alastair M. Thompson, Alain Viari, Matthew E. Hurles, Serena Nik-Zainal, Peter J. Campbell, Michael R. Stratton
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A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
Dominik Glodzik, Sandro Morganella, Helen Davies, Peter T Simpson, Yilong Li, Xueqing Zou, Javier Diez-Perez, Johan Staaf, Ludmil B Alexandrov, Marcel Smid, Arie B Brinkman, Inga Hansine Rye, Hege Russnes, Keiran Raine, Colin A Purdie, Sunil R Lakhani, Alastair M Thompson, Ewan Birney, Hendrik G Stunnenberg, Marc J van de Vijver, John W M Martens, Anne-Lise Børresen-Dale, Andrea L Richardson, Gu Kong, Alain Viari, Douglas Easton, Gerard Evan, Peter J Campbell, Michael R Stratton, Serena Nik-Zainal
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EZH2 alterations in follicular lymphoma: biological and clinical correlations
Sarah Huet, Luc Xerri, Bruno Tesson, Sylvain Mareschal, Sébastien Taix, Lenaïg Mescam-Mancini, Emilie Sohier, Marjorie Carrère, Julien Lazarovici, Olivier Casasnovas, Laurie Tonon, Sandrine Boyault, Sandrine Hayette, Corinne Haioun, Bettina Fabiani, Alain Viari, Fabrice Jardin, Gilles Salles
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Apport et défis des Big Data en cancérologie
Pierre Saintigny, Philippe Foy, Anthony Ferrari, Philippe Cassier, Alain Viari, Alain Puisieux
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BCL2 mutations do not confer adverse prognosis in follicular lymphoma patients treated with rituximab
Sarah Huet, Edith Szafer-Glusman, Bruno Tesson, Luc Xerri, Wayne J. Fairbrother, Kiran Mukhyala, Chris Bolen, Elizabeth Punnoose, Laurie Tonon, Catherine Chassagne-Clément, Pierre Feugier, Alain Viari, Fabrice Jardin, Gilles Salles, Pierre Sujobert
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The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade
P. Foy, Chloé Bertolus, Marie-Cécile Michallet, Sophie Deneuve, R. Incitti, Nathalie Bendriss-Vermare, Marie-Alexandra Albaret, Sandra Ortiz-Cuaran, E. Thomas, A. Colombe, C. Py, Nicolas Gadot, Jean-Philippe Michot, Jerôme Fayette, Alain Viari, Benoit van den Eynde, Patrick Goudot, Mojgan Devouassoux-Shisheboran, Alain Puisieux, Christophe Caux, Philippe Zrounba, Sylvie Lantuejoul, Pierre Saintigny
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A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes
Jean-Philippe Foy, Louis Bazire, Sandra Ortiz-Cuaran, Sophie Deneuve, Janice Kielbassa, Emilie Thomas, Alain Viari, Alain Puisieux, Patrick Goudot, Chloé Bertolus, Nicolas Foray, Youlia Kirova, Pierre Verrelle, Pierre Saintigny
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A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes
Jean-Philippe Foy, Louis Bazire, Sandra Ortiz-Cuaran, Sophie Deneuve, Janice Kielbassa, Emilie Thomas, Alain Viari, Alain Puisieux, Patrick Goudot, Chloé Bertolus, Nicolas Foray, Youlia Kirova, Pierre Verrelle, Pierre Saintigny
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A gene-expression profiling score for prediction of outcome in patients with follicular lymphoma: a retrospective training and validation analysis in three international cohorts
Sarah Huet, Bruno Tesson, Jean-Philippe Jais, Andrew Feldman, Laura Magnano, Emilie Thomas, Alexandra Traverse-Glehen, Benoit Albaud, Marjorie Carrère, Luc Xerri, Stephen Ansell, Lucile Baseggio, Cecile Reyes, Karin Tarte, Sandrine Boyault, Corinne Haioun, Brian Link, Pierre Feugier, Armando Lopez-Guillermo, Herve Tilly, Pauline Brice, Sandrine Hayette, Fabrice Jardin, Fritz Offner, Pierre Sujobert, David Gentien, Alain Viari, Elias Campo, James Cerhan, Gilles Salles
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Immunological and classical subtypes of oral premalignant lesions
Jean-Philippe Foy, Chloé Bertolus, Sandra Ortiz-Cuaran, Marie-Alexandra Albaret, William Williams, Wenhua Lang, Solène Destandau, Geneviève De Souza, Emilie Sohier, Janice Kielbassa, Emilie Thomas, Sophie Deneuve, Patrick Goudot, Alain Puisieux, Alain Viari, Li Mao, Christophe Caux, Scott M. Lippman, Pierre Saintigny
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Integrated analysis highlights APC11 protein expression as a likely new independent predictive marker for colorectal cancer
Youenn Drouet, Isabelle Treilleux, Alain Viari, Sophie Léon, Mojgan Devouassoux-Shisheboran, Nicolas Voirin, Christelle de la Fouchardiere, Brigitte Manship, Alain Puisieux, Christine Lasset, Caroline Moyret-Lalle
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Mutational Profile of Aggressive, Localised Prostate Cancer from African Caribbean Men Versus European Ancestry Men
Laurie Tonon, Gaëlle Fromont, Sandrine Boyault, Emilie Thomas, Anthony Ferrari, Anne-Sophie Sertier, Janice Kielbassa, Vincent Le Texier, Aurélie Kamoun, Nabila Elarouci, Jacques Irani, Luc Multigner, Ivo Gut, Marta Gut, Pascal Blanchet, Aurélien de Reyniès, Geraldine Cancel-Tassin, Alain Viari, Olivier Cussenot
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Peptimapper: proteogenomics workflow for the expert annotation of eukaryotic genomes
Laetitia Guillot, Ludovic Delage, Alain Viari, Yves Vandenbrouck, Emmanuelle Com, Andrés Ritter, Régis Lavigne, Dominique Marie, Pierre Peterlongo, Philippe Potin, Charles Pineau
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The circular RNome of primary breast cancer
Marcel Smid, Saskia Wilting, Katharina Uhr, F. Germán Rodríguez-González, Vanja de Weerd, Wendy J.C. Prager-van der Smissen, Michelle van der Vlugt-Daane, Anne van Galen, Serena Nik-Zainal, Adam Butler, Sancha Martin, Helen Davies, Johan Staaf, Marc van de Vijver, Andrea Richardson, Gaëten Macgrogan, Roberto Salgado, Gert G.G.M. van den Eynden, Colin Purdie, Alastair Thompson, Carlos Caldas, Paul Span, Fred C.G.J. Sweep, Peter Simpson, Sunil Lakhani, Steven van Laere, Christine Desmedt, Angelo Paradiso, Jorunn Eyfjord, Annegien Broeks, Anne Vincent-Salomon, Andrew Futreal, Stian Knappskog, Tari King, Alain Viari, Anne-Lise Børresen-Dale, Hendrik Stunnenberg, Mike Stratton, John Foekens, Anieta Sieuwerts, John W.M. Martens
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Molecular screening program to select molecular-based recommended therapies for metastatic cancer patients: analysis from the ProfiLER trial
Olivier Trédan, Qiang Wang, Daniel Pissaloux, Pierre Cassier, Arnaud de la Fouchardière, Jérôme Fayette, Françoise Desseigne, Isabelle Ray-Coquard, Christelle de la Fouchardière, Didier Frappaz, Pierre Heudel, Alice Bonneville-Levard, Aude Flechon, Mathieu Sarabi, Philippe Guibert, Thomas Bachelot, Maurice Pérol, Benoit You, Nathalie Bonnin, Olivier Collard, Cécile Leyronnas, Valéry Attignon, Christian Baudet, Emilie Sohier, Jean-Philippe Villemin, Alain Viari, Sandrine Boyault, Sylvie Lantuejoul, Sandrine Paindavoine, Isabelle Treillleux, Cécile Rodriguez, Vincent Agrapart, Veronique Corset, Gwenaelle Garin, Sylvie Chabaud, David Perol, Jean-Yves Blay
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Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis
Marc Bonnin, Nadim Fares, Barbara Testoni, Yann Estornes, Kathrin Weber, Béatrice Vanbervliet, Lydie Lefrancois, Amandine Garcia, Alain Kfoury, Floriane Pez, Isabelle Coste, Pierre Saintigny, Alain Viari, Kévin Lang, Baptiste Guey, Valérie Hervieu, Brigitte Bancel, Birke Bartoch, David Durantel, Toufic Renno, Philippe Merle, Serge Lebecque
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Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade
Tala Shekarian, Eva Sivado, Anne-Catherine Jallas, Stephane Depil, Janice Kielbassa, Isabelle Janoueix-Lerosey, Gregor Hutter, Nadège Goutagny, Christophe Bergeron, Alain Viari, Sandrine Valsesia-Wittmann, Christophe Caux, Aurélien Marabelle