Showing results 6421 to 6434 on 6434 in total
Eric Tannier
Cedric Chauve, Haris Gavranovic, Aida Ouangraoua, Eric Tannier
G. David, K. Blondeau, M. Schiltz, Simon Penel, A. Lewit-Bentley
S. Ruuskanen, Blandine Doligez, B. Tschirren, N. Pitala, L. Gustafsson, G.G. Groothuis, T. Laaksonen
E.A. Hornett, A.M. Duplouy, N. Davies, G.K. Roderick, N. Wedell, G.D. Hurst, S. Charlat
G. Bourgoin, Alice Laurent, Pascal Marchand, Jeanne Duhayer, Marie-Thérèse Poirel, Patricia Michel, Christian Itty, Mathieu Garel
Nicolas Courbin, Andrew Loveridge, Hervé Fritz, David Macdonald, Rémi Patin, Marion Valeix, Simon Chamaillé-Jammes
Age is the highest important risk factor for the most prevalent human diseases, including cancer. Telomere shortening is thought to play a central role in the aging process in humans. The link between telomeres and aging is highlighted by the fact that genetic diseases causing telomerase deficiency are associated with premature aging and increased risk of cancer. For the last two decades, this link has been investigated using long telomere mouse models. However, zebrafish has recently emerged as a powerful and complementary model system to study telomere biology. Zebrafish possess human-like telomeres that progressively decline with age. The extensive characterisation of its well-conserved molecular and cellular physiology makes this vertebrate an excellent model to unravel the underlying relationship between telomere shortening, tissue regeneration, aging and disease. In our work, we explore how telomere attrition contributes to cellular senescence, organ dysfunction, aging and disease.
Adrian A Davin, Theo Tricou, Eric Tannier, Damien M. de Vienne, Gergely J Szöllosi
Théo Arber, Tristan Jaouen, Séphora Campoy, Muriel Rabilloud, Rémi Souchon, Fatima Abbas, Paul Moldovan, Marc Colombel, Sébastien Crouzet, Alain Ruffion, Paul Neuville, Olivier Rouvière
Mª José Izquierdo-Rico, Carla Moros-Nicolás, Míriam Pérez-Crespo, Ricardo Laguna-Barraza, Alfonso Gutiérrez-Adán, Frédéric Veyrunes, José Ballesta, Vincent Laudet, P Chevret, Manuel Avilés
Romain Amiot, Xu Wang, Shuo Wang, Christophe Lécuyer, Jean-Michel Mazin, Jinyou Mo, Jean-Pierre Flandrois, François Fourel, Xiaolin Wang, Xing Xu, Zhijun Zhang, Zhonghe Zhou
Christophe Lécuyer, Antonio Sanchez Marco, Alejandro Lomoschitz, Juan-Francisco Betancort, François Fourel, Romain Amiot, Thibault Clauzel, Jean-Pierre Flandrois, Joaquín Meco
E. Lerat, H. Ochman