Showing results 5801 to 5820 on 7051 in total
Laure Ségurel, Begoña Martínez-Cruz, Lluis Quintana-Murci, Patricia Balaresque, Myriam Georges, Tatiana Hegay, Almaz Aldashev, Firuza Nasyrova, Mark A Jobling, Evelyne Heyer, Renaud Vitalis
M. Tafani, A. Cohas, C. Bonenfant, Jean-Michel Gaillard, S. Lardy, D. Allaine
Ludovic Dutoit, Carina Mugal, Paulina Bolívar, Mi Wang, Krystyna Nadachowska-Brzyska, Linnéa Smeds, Homa Yazdi, Lars Gustafsson, Hans Ellegren
Hugo Cayuela, Jean-François Lemaître Lemaître, Jean‐paul Léna, Victor Ronget, Iñigo Martínez‐solano, Erin Muths, David Pilliod, Benedikt Schmidt, Gregorio Sánchez‐montes, Jorge Gutiérrez‐rodríguez, Graham Pyke, Kurt Grossenbacher, Omar Lenzi, Jaime Bosch, Karen Beard, Lawrence Woolbright, Brad Lambert, David Green, Nathalie Jreidini, Justin Garwood, Robert Fisher, Kathleen Matthews, David Dudgeon, Anthony Lau, Jeroen Speybroeck, Rebecca Homan, Robert Jehle, Eyup Başkale, Emiliano Mori, Jan Arntzen, Pierre Joly, Rochelle Stiles, Michael Lannoo, John Maerz, Winsor Lowe, Andrés Valenzuela‐sánchez, Ditte Christiansen, Claudio Angelini, Jean‐marc Thirion, Juha Merilä, Guarino Colli, Mariana Vasconcellos, Taissa Boas, Ísis da C. Arantes, Pauline Levionnois, Beth Reinke, Cristina Vieira, Gabriel Marais, Jean‐michel Gaillard, David Miller
Morgane Tidière, Peter Müller, Alexander Sliwa, Aurélie Siberchicot, Guillaume Douay
Lucas Lalande, Virpi Lummaa, Htoo Aung, Win Htut, U. Kyaw Nyein, Vérane Berger, Michael Briga
Aurore Gallot-Le Grand, Shuji Shigenobu, Tomomi Hashiyama, Stéphanie Jaubert, Denis Tagu
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R.B. Huey, B. Moreteau, J.-C. Moreteau, Patricia Gibert, G.W. Gilchriste, A.R. Ivesf, T. Garland, J.R. David
Pauline Vuarin, Pierre-Yves Henry, Philippe Guesnet, Jean Marc Alessandri, Fabienne Aujard, Martine Perret, Fabien Pifferi
When humans reason about functional structures of RNA, they speak of long hairpins with miRNA precursors, of clover leaf structures with tRNA, of neighouring hairpins with attenuators, and so on. Most of the time, we do not care about individual base pairs or helix sizes, while the overall arrangment of helices and loops really matters.RNA folding programs, however, used to be ignorant of abstraction in RNA, deceiving us with a single, minimum free energy structure, or overwhelming us with a plethora of near-optimal structures, most of which are quite similar and therefore redundant.RNA shape abstraction alleviates this situation. RNA shapes are abstract structure images, retaining adjacency and nesting of structural features, but disregarding size information. Shape abstraction integrates well with dynamic programming algorithms, and hence it can be applied during structure prediction rather than afterwards. This avoids exponential explosion in the near-optimal folding space, and provides a non-heuristic and complete account of an RNA molecule's structural inclinations. Quite magically, some long-studied problems become easy.In the presentation, I will shortly review the notion of abstract shapes. I will then discuss several applications of this concept, including a highly effective filtering method when working with structural classes of RNA described by covariance models, such as provided by the Rfam data base.
Thèse de Stéphanie Periquet - Jeudi 10 juillet 2014 - 14:30 - Salle de conférence de la Bibliothèque - La Doua
Sandrine Philippe, Christian Ducrot, Pascal Roy, Laurent Remontet, Nathalie Jarrige, Didier Calavas
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Matteo Brilli, Pietro Liò, Vincent Lacroix, Marie-France Sagot
Lucie Debeffe, Jean-François Lemaître, Ulrika Alm Bergvall, A.J. Mark Hewison, Jean-Michel Gaillard, Nicolas Morellet, Goulard Michel, Chloe Monestier, Martens David, Hélène Verheyden, Leif Jaderberg, Cécile Vanpe, Petter Kjellander
Marianne Haguenauer, P. Fargier, Pierre Legreneur, Anne-Béatrice Dufour, G. Cogerino, M. Begon, K.M. Monteil
Jean-François Lemaître Lemaître, Jeffrey Carbillet, Benjamin Rey, Rupert Palme, Hannah Froy, Rachael V. Wilbourn, Sarah L. Underwood, Louise Cheynel, Jean-Michel Gaillard, A. J. Mark Hewison, Hélène Verheyden, François Débias, Jeanne Duhayer, Corinne Régis, Sylvia Pardonnet, Maryline Pellerin, Daniel H. Nussey, Emmanuelle Gilot-Fromont
M. Philippe, Sylvain Goutelle, J. Guitton, X. Fonrose, C. Bergeron, Pascal Girard, Y. Bertrand, N. Bleyzac