Affichage des résultats 1021 à 1040 sur 1601 au total
Deux équipes présentent des résultats ou des questions qui leurs sont propres afin de favoriser de nouvelles discussions au sein du laboratoire.
Deux équipes présentent des résultats ou des questions qui leurs sont propres afin de favoriser de nouvelles discussions au sein du laboratoire.
Deux équipes présentent des résultats ou des questions qui leurs sont propres afin de favoriser de nouvelles discussions au sein du laboratoire.«Telling metabolic stories to explore metabolomics data: A case study on the Yeast response to cadmium exposure» Cecilia Coimbra Klein et«Sénescence et sélection sexuelle chez les populations naturelles de vertébrés» Jean-Francois Lemaitre
Deux équipes présentent des résultats ou des questions qui leurs sont propres afin de favoriser de nouvelles discussions au sein du laboratoire.
Deux équipes présentent des résultats ou des questions qui leurs sont propres afin de favoriser de nouvelles discussions au sein du laboratoire.
Deux équipes présentent des résultats ou des questions qui leurs sont propres afin de favoriser de nouvelles discussions au sein du laboratoire.
Papers evaluating measures of explained variation, or similar indices, invariably use independence from censoring as the most important criterion. And they invariably end up suggesting that some measures meet this criterion, and some don't, leading to a conclusion that the first are better than the second. As a consequence, users are offered measures that cannot be used with time-dependant covariates and effects, not to mention extensions to repeated events or multi state models. We explain in this paper that the above mentioned criterion is of no use in studying such measures, since it simply favours those that make an implicit assumption of a model being valid everywhere. Measures not making such an assumption are disqualified, even though they are better in every other respect. We show that if these, allegedly inferior, measures are allowed to make the same assumption, they are easily corrected to satisfy the `independent-from-censoring' criterion. Even better, it is enough to make such an assumption only for the times greater than the last observed failure time $tau$. Which, in contrast with the `preferred' measures, makes it possible to use all the modelling flexibility up-to $tau$, and assume whatever one wants after $tau$. As a consequence, we claim that measures being proffered as better in the existing reviews, are exactly those that are inferior
Research in the lab focuses on the evolution and ecology of associations between hosts (mostly insects!) and the organisms that infect them, from parasites and pathogens to obligate mutualists, from nematodes and parasitoids to inherited bacterial endosymbionts. Interests also include selfish genetic elements, disease ecology and evolution, unusual genetic systems and life histories, and insects in general.https://perlmanlab.weebly.comet un article récent décrivant un remarquable système de distorsion du sexe et autres bizarreries génétiques chez les « booklice » :https://www.sciencedirect.com/science/article/pii/S0960982218313642
In the absence of a clear understanding of its genetic basis, Cytoplasmic Incompatibility (CI) has so far been conceptualized using a simple toxin-antitoxin model. Under this model, a symbiont's ³compatibility type² is determined by the specific interaction between two components: a modification factor (mod, expressed in sperm) and a rescue factor (resc, expressed in the eggs). Here we confront this model to a well studied, complex and puzzling CI study system: the mosquito Culex pipiens. We show that a more elaborate model is required to account for the observed pattern, including multiple mod and resc genes, and possibly quantitative variation in gene products. We develop such a model and fit its parameters to the data using a parsimony approach. We thereby produce explicit predictions with regards to the genetic architecture of CI; namely, we infer that at least five mod / resc pairs are required to explain the data. These predictions provide a starting point for future genetic and genomic analyses of CI and will hopefully contribute to the decryption of its molecular basis.
A Postdoctoral Research Associate is available at the Claude Bernard University – Lyon 1 (France) for modelling the impact of farmers’ behaviour on the spread of infectious diseases in livestock and its implication on disease mitigation strategies.
Ophélia Gestin, a remporté, le 9 Octobre dernier, le prix du jury « Meilleure vulgarisation » du « Festival du film [pas trop] scientifique »
Thèse de Hai Ha LE le mercredi 4 octobre 2017 à 15 h, salle des thèses Laënnec