Statistiques et Modélisation pour les Sciences de la Santé

GEMO, a National Resource to Study Genetic Modifiers of Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Pathogenic Variant Carriers

Fabienne Lesueur, Noura Mebirouk, Yue Jiao, Laure Barjhoux, Muriel Belotti, Maïté Laurent...

Frontiers in Oncology . 8 : 490

DOI: 10.3389/fonc.2018.00490

2018

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Socioeconomic environment and disparities in cancer survival for 19 solid tumor sites: An analysis of the French Network of Cancer Registries (FRANCIM) data

Laure Tron, Aurélien Belot, Mathieu Fauvernier, Laurent Remontet, Nadine Bossard, Ludivine Launay...

International Journal of Cancer . 144 ( 6 ) : 1262-1274

DOI: 10.1002/ijc.31951

2018

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Risk of thrombosis with anti-phospholipid syndrome in systemic lupus erythematosus treated with thrombopoietin-receptor agonists.

Zelie Guitton, Louis Terriou, Jean-Christophe Lega, Raphaele Nove-Josserand, Miguel Hie, Zahir Amoura...

Rheumatology . 57 : 1432–1438

DOI: 10.1093/rheumatology/key119

2018

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Donor sperm insemination after failed intra-couple intracytoplasmic sperm injection

Sylviane Hennebicq, Oxana Blagosklonov, Florence Eustache, Aline Papaxanthos, Véronique Drouineaud, Catherine Guillemain...

Systems Biology in Reproductive Medicine . 64 ( 2 ) : 130-137

DOI: 10.1080/19396368.2017.1382608

2018

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A Generic Model for Quantitative Prediction of Interactions Mediated by Efflux Transporters and Cytochromes: Application to P-Glycoprotein and Cytochrome 3A4

Michel Tod, Sylvain Goutelle, N. Bleyzac, L. Bourguignon

Clinical Pharmacokinetics . 58 ( 4 ) : 503-523

DOI: 10.1007/s40262-018-0711-0

2018

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Comment on: MIC-based dose adjustment: facts and fables

Sylvain Goutelle, Charlotte Genestet, Florence Ader, Gérard Lina, Oana Dumitrescu

Journal of Antimicrobial Chemotherapy . 73 ( 9 ) : 2584-2585

DOI: 10.1093/jac/dky131

2018

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Population Pharmacokinetic Study of Amoxicillin-Treated Burn Patients Hospitalized at a Swiss Tertiary-Care Center

Anne Fournier, Sylvain Goutelle, Yok-Ai Que, Philippe Eggimann, Olivier Pantet, Farshid Sadeghipour...

Antimicrobial Agents and Chemotherapy . 62 ( 9 )

DOI: 10.1128/AAC.00505-18

2018

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Maximal concentration of intravenous busulfan as a determinant of veno-occlusive disease: a pharmacokinetic-pharmacodynamic analysis in 293 hematopoietic stem cell transplanted children

Michaël Philippe, Michael Neely, Teresa Rushing, Yves Bertrand, Nathalie Bleyzac, Sylvain Goutelle

Bone Marrow Transplantation . 54 ( 3 ) : 448-457

DOI: 10.1038/s41409-018-0281-7

2018

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[Pharmacokinetic risk factors of beta-blockers overdose in the elderly: Case report and pharmacology approach].

L. Lafarge, L. Bourguignon, N. Bernard, T. Vial, M.-J. Dehan-Moya, B. de la Gastine...

Annales de Cardiologie et d'Angéiologie . 67 ( 2 ) : 91-97

DOI: 10.1016/j.ancard.2018.02.001

2018

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Identification of Cytochrome P450-Mediated Drug–Drug Interactions at Risk in Cases of Gene Polymorphisms by Using a Quantitative Prediction Model

Nicolas Fermier, Laurent Bourguignon, Sylvain Goutelle, Nathalie Bleyzac, Michel Tod

Clinical Pharmacokinetics . 57 ( 12 ) : 1581-1591

DOI: 10.1007/s40262-018-0651-8

2018

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Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation

Jean-François Obadia, D. Messika-Zeitoun, G. Leurent, B. Iung, G. Bonnet, N. Piriou...

New England Journal of Medicine . 379 ( 24 ) : 2297--2306

DOI: 10.1056/NEJMoa1805374

2018

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Immunosuppressive regimen and risk for de novo malignancies after liver transplantation for alcoholic liver disease

Jérôme Dumortier, Delphine Maucort-Boulch, Domitille Poinsot, Elsa Thimonier, Christine Chambon-Augoyard, Emilie Ducroux...

Clinics and Research in Hepatology and Gastroenterology . 42 ( 5 ) : 427-435

DOI: 10.1016/j.clinre.2018.04.011

2018

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Refractory diffuse large B-cell lymphoma after first-line immuno-CT: Treatment options and outcomes

Lauriane Filliatre-Clement, Delphine Maucort-Boulch, Estelle Bourbon, Lionel Karlin, Violaine Safar, Emmanuel Bachy...

Hematological Oncology . 36 ( 3 ) : 533-542

DOI: 10.1002/hon.2512

2018

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A simplified scoring system in de novo follicular lymphoma treated initially with immunochemotherapy

Emmanuel Bachy, Matthew Maurer, Thomas Habermann, Bénédicte Gelas-Dore, Delphine Maucort-Boulch, Jane Estell...

Blood . 132 ( 1 ) : 49-58

DOI: 10.1182/blood-2017-11-816405

2018

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Fraction and incidence of liver cancer attributable to hepatitis B and C viruses worldwide

Delphine Maucort-Boulch, Catherine de Martel, Silvia Franceschi, Martyn Plummer

International Journal of Cancer . 142 ( 12 ) : 2471-2477

DOI: 10.1002/ijc.31280

2018

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Real life management of patients hospitalized with multiple myeloma in France

Charles Dumontet, Sandrine Couray-Targe, Marion Teisseire, Lionel Karlin, Delphine Maucort-Boulch

PLoS ONE . 13 ( 5 ) : e0196596

DOI: 10.1371/journal.pone.0196596

2018

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Focal myositis

Laure Gallay, Arnaud Hot, Philippe Petiot, Françoise Thivolet-Bejui, Delphine Maucort-Boulch, Nathalie Streichenberger

Neurology . 90 ( 12 ) : e1013-e1020

DOI: 10.1212/WNL.0000000000005160

2018

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Impact des anticoagulants sur le risque hémorragique au cours de l’HoLEP : étude monocentrique de 156 patients

P. Neuville, R. Codas, E. Ravier, D. Maucort-Boulch, L. Badet, H. Fassi-Fehri

Progrès en Urologie . 28 ( 2 ) : 128-134

DOI: 10.1016/j.purol.2017.10.013

2018

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Incidence of Cystoid Macular Edema After Descemet Membrane Endothelial Keratoplasty

Viridiana Kocaba, Romain Mouchel, Jacques Fleury, Anne-Sophie Marty, Hélène Janin-Manificat, Delphine Maucort-Boulch...

Cornea . 37 ( 3 ) : 277-282

DOI: 10.1097/ICO.0000000000001501

2018

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Effect of Buparlisib, a Pan-Class I PI3K Inhibitor, in Refractory Follicular and Poorly Differentiated Thyroid Cancer

Francoise Borson-Chazot, Emmanuelle Dantony, Frederic Illouz, Jonathan Lopez, Patricia Niccoli, Johanna Wassermann...

Thyroid . 28 ( 9 ) : 1174-1179

DOI: 10.1089/thy.2017.0663

2018

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Effects on Mortality and Cardiovascular Events of Adherence to Guideline-Recommended Therapy 4 Years after Lower Extremity Arterial Revascularization

Martina Thiney, Nellie Della Schiava, René Ecochard, Patrick Feugier, Patrick Lermusiaux, Antoine Millon...

Annals of Vascular Surgery . 52 : 138-146

DOI: 10.1016/j.avsg.2018.03.021

2018

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Construction and feasibility study of the SOFMER Activity Score (SAS), a new assessment of physical and cognitive activity

M.D. Morard, S. Gonzalez-Monge, P. Rippert, S. Roche, J.C. Bernard, D. Lagauche...

Annals of Physical and Rehabilitation Medicine . 61 ( 5 ) : 315-322

DOI: 10.1016/j.rehab.2018.04.006

2018

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Multiple Micronutrient Plasma Level Changes Are Related to Oxidative Stress Intensity in Critically Ill Children

Frédéric V. Valla, Muriel Bost, Sylvain Roche, Marion Pitance, Charlotte Cuerq, Jenna Ridout...

Pediatric Critical Care Medicine . 19 ( 9 ) : e455

DOI: 10.1097/PCC.0000000000001626

2018

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Association between Peripheral Leptin and Adiponectin Levels and Cognitive Decline in Patients with Neurocognitive Disorders \textgreater= 65 Years

T. Gilbert, S. Roche, Emilie Blond, J. Y. Bar, Jocelyne Drai, Charlotte Cuerq...

Journal of Alzheimer's Disease . 66 ( 3 ) : 1255--1264

2018

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Transcriptional regulation of CRMP5 controls neurite outgrowth through Sox5

Nicolas Naudet, Aubin Moutal, Hong Nhung Vu, Naura Chounlamountri, Chantal Watrin, Sylvie Cavagna...

Cellular and Molecular Life Sciences . 75 ( 1 ) : 67-79

DOI: 10.1007/s00018-017-2634-6

2018

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Contribution of mutations in genes of the surfactant system to idiopathic interstitial pneumonia (IIP)

Nadia Nathan, Marie Legendre, Emilie Filhol-Blin, Raphael Borie, Diane Bouvry, Mickael Afanetti...

ERS International Congress 2018 abstracts . : OA547

DOI: 10.1183/13993003.congress-2018.OA547

2018

Acte de congrès

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Functional assessment of newly identified SFTPA1 and SFTPA2 mutations in patients with idiopathic interstitial pneumonia (IIP) and lung cancer.

Nadia Nathan, Marie Legendre, Emilie Filhol-Blin, Raphaël Borie, Diane Bouvry, Caroline Kannengiesser...

uropean Respiratory Society (ERS) Congress, .

2018

Acte de congrès

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Functional assessment of newly identified SFTPA1 and SFTPA2 mutations in patients with idiopathic interstitial pneumonia (IIP) and lung cancer28th International Congress of the European-Respiratory-Society (ERS)

Nadia Nathan, Marie Legendre, Emilie Filhol-Blin, Raphael Borie, Diane Bouvry, Caroline Kannengiesser...

28th International Congress of the European-Respiratory-Society (ERS) .

DOI: 10.1183/13993003.congress-2018.PA2235

2018

Acte de congrès

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Down syndrome and pulmonary hemosiderosis: an under-recognized association

Aurelia Alimi, Jessica Taytard, Rola Abou Taam, Véronique Houdouin, Aude Forgeron, Marc Lubrano Lavadera...

European Respiratory Society (ERS) Congress .

2018

Acte de congrès

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Place de l’analyse des gènes du surfactant dans la démarche diagnostique des pneumopathies interstitielles diffuses de l’enfant et l’adulte

Nadia Nathan, Marie Legendre, Raphaël Borie, Diane Bouvry, Mickael Afanetti, Juliette Albuisson...

Assises de Génétique Humaine et Médicale .

2018

Poster

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Statistiques et Modélisation pour les Sciences de la Santé

Equipe Biostatistiques Santé

Equipe Evaluation et Modélisation des Effets Thérapeutiques

Publications

GEMO, a National Resource to Study Genetic Modifiers of Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Pathogenic Variant Carriers

Socioeconomic environment and disparities in cancer survival for 19 solid tumor sites: An analysis of the French Network of Cancer Registries (FRANCIM) data

Risk of thrombosis with anti-phospholipid syndrome in systemic lupus erythematosus treated with thrombopoietin-receptor agonists.

Donor sperm insemination after failed intra-couple intracytoplasmic sperm injection

A Generic Model for Quantitative Prediction of Interactions Mediated by Efflux Transporters and Cytochromes: Application to P-Glycoprotein and Cytochrome 3A4

Comment on: MIC-based dose adjustment: facts and fables

Population Pharmacokinetic Study of Amoxicillin-Treated Burn Patients Hospitalized at a Swiss Tertiary-Care Center

Maximal concentration of intravenous busulfan as a determinant of veno-occlusive disease: a pharmacokinetic-pharmacodynamic analysis in 293 hematopoietic stem cell transplanted children

[Pharmacokinetic risk factors of beta-blockers overdose in the elderly: Case report and pharmacology approach].

Identification of Cytochrome P450-Mediated Drug–Drug Interactions at Risk in Cases of Gene Polymorphisms by Using a Quantitative Prediction Model

Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation

Immunosuppressive regimen and risk for de novo malignancies after liver transplantation for alcoholic liver disease

Refractory diffuse large B-cell lymphoma after first-line immuno-CT: Treatment options and outcomes

A simplified scoring system in de novo follicular lymphoma treated initially with immunochemotherapy

Fraction and incidence of liver cancer attributable to hepatitis B and C viruses worldwide

Real life management of patients hospitalized with multiple myeloma in France

Focal myositis

Impact des anticoagulants sur le risque hémorragique au cours de l’HoLEP : étude monocentrique de 156 patients

Incidence of Cystoid Macular Edema After Descemet Membrane Endothelial Keratoplasty

Effect of Buparlisib, a Pan-Class I PI3K Inhibitor, in Refractory Follicular and Poorly Differentiated Thyroid Cancer

Effects on Mortality and Cardiovascular Events of Adherence to Guideline-Recommended Therapy 4 Years after Lower Extremity Arterial Revascularization

Construction and feasibility study of the SOFMER Activity Score (SAS), a new assessment of physical and cognitive activity

Multiple Micronutrient Plasma Level Changes Are Related to Oxidative Stress Intensity in Critically Ill Children

Association between Peripheral Leptin and Adiponectin Levels and Cognitive Decline in Patients with Neurocognitive Disorders \textgreater= 65 Years

Transcriptional regulation of CRMP5 controls neurite outgrowth through Sox5

Contribution of mutations in genes of the surfactant system to idiopathic interstitial pneumonia (IIP)

Functional assessment of newly identified SFTPA1 and SFTPA2 mutations in patients with idiopathic interstitial pneumonia (IIP) and lung cancer.

Functional assessment of newly identified SFTPA1 and SFTPA2 mutations in patients with idiopathic interstitial pneumonia (IIP) and lung cancer28th International Congress of the European-Respiratory-Society (ERS)

Down syndrome and pulmonary hemosiderosis: an under-recognized association

Place de l’analyse des gènes du surfactant dans la démarche diagnostique des pneumopathies interstitielles diffuses de l’enfant et l’adulte

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