Statistiques et Modélisation pour les Sciences de la Santé

A pyriform sinus cancer organ preservation strategy comprising induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil, followed by potentiated radiotherapy: a multicenter, retrospective study

P. Ceruse, A. Cosmidis, A. Belot, Muriel Rabilloud, C. Fuchsmann, M. Poupart...

Anti-cancer Drugs . 25 : 970-5

DOI: 10.1097/CAD.0000000000000126

2014

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Cardiovascular Events and Bleeding Risk Associated With Intravitreal Antivascular Endothelial Growth Factor Monoclonal Antibodies: Systematic Review and Meta-analysis

M. Thulliez, D. Angoulvant, M. L. Le Lez, Annie-Pierre Jonville-Bera, P. J. Pisella, François Gueyffier...

JAMA Ophthalmology . 132 ( 11 ) : 1317-26

DOI: 10.1001/jamaophthalmol.2014.2333

2014

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Guidelines for Managing High Blood Pressure

Dk. Cundiff, François Gueyffier, Jm. Wright

Journal of the American Medical Association . 312 ( 3 ) : 293-294

DOI: 10.1001/jama.2014.6590

2014

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Multivariate meta-analysis using individual participant data

R. D. Riley, M. J. Price, D. Jackson, M. Wardle, François Gueyffier, J. Wang...

Research Synthesis Methods . 6 ( 2 ) : 157-174

DOI: 10.1002/jrsm.1129

2014

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Can we identify response markers to antihypertensive drugs? First results from the Ideal Trial.

Gueyffier F., Subtil F., Bejan-Angoulvant T., Yves Zerbib, Baguet Jp, Boivin Jm...

Journal of Human Hypertension . : doi: 10.1038/jhh.2014.29

2014

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Determinants of torsades de pointes in older patients with drug-associated long QT syndrome: a case-control study

Sylvain Goutelle, E. Sidolle, M. Ducher, J. Caron, Q. Timour, Patrice Nony...

Drugs & aging . 31 : 601-9

2014

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Exposure to anticholinergic and sedative drugs, risk of falls, and mortality: an elderly inpatient, multicenter cohort

V. Dauphinot, R. Faure, S. Omrani, Sylvain Goutelle, Laurent Bourguignon, P. Krolak-Salmon...

Journal of clinical psychopharmacology . 34 : 565-70

DOI: 10.1097/JCP.0000000000000195

2014

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Pharmacokinetic Drug Interaction Between Cyclosporine and Imatinib in Bone Marrow Transplant Children and Model-Based Reappraisal of Imatinib Drug Interaction Profile

Nathalie Bleyzac, K. Kebaili, V. Mialou, Y. Bertrand, Sylvain Goutelle

Therapeutic Drug Monitoring . 36 : 724-729

2014

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Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children

E. Bernard, Sylvain Goutelle, Y. Bertrand, Nathalie Bleyzac

The Annals of Pharmacotherapy . 48 : 1580-4

DOI: 10.1177/1060028014550644

2014

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Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial

J. Taieb, J. Tabernero, E. Mini, Fabien Subtil, G. Folprecht, Jl. van Laethem...

Lancet Oncology . 15 : 862-873

2014

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Modeling the seasonality of Anopheles gambiae s.s. biting rates in a South Benin sanitary zone

O. Boussari, Fabien Subtil, N. Moiroux, A. Djenontin, J. Iwaz, V. Corbel...

Transactions of The Royal Society of Tropical Medicine and Hygiene . 108 : 237-43

DOI: 10.1093/trstmh/tru027

2014

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Prostate Focal Peripheral Zone Lesions: Characterization at Multiparametric MR Imaging--Influence of a Computer-aided Diagnosis System

E. Niaf, C. Lartizien, F. Bratan, L. Roche, Muriel Rabilloud, F. Mège-Lechevallier...

Radiology . 271 ( 3 ) : 761 -769

DOI: 10.1148/radiol.14130448

2014

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Spatial distribution of Toxoplasma gondii oocysts in soil in a rural area: Influence of cats and land use.

Cécile Gotteland, Emmanuelle Gilot-Fromont, Laurence Voutquenne-Nazabadioko, Marie-Lazarine Poulle, Emilie Dupuis, Marie-Laure Dardé...

Veterinary Parasitology . 205 ( 3-4 ) : 629-37

2014

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Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 2: 6-mercaptopurine and its interaction with methotrexate

Kayode Ogungbenro, Leon Aarons, A Bajard, C Ballot, Y Bertrand, F Bretz...

Journal of Pharmacokinetics and Pharmacodynamics . 41 ( 2 ) : 173-185

2014

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Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 1: methotrexate

K. Ogungbenro, L. Aarons, The Cresim Project Group, The Epi-Cresim Project Groups, Catherine Cornu, Behrouz Kassai...

Journal of pharmacokinetics and pharmacodynamics . 41 : 159-71

2014

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A physiologically based pharmacokinetic model for Valproic acid in adults and children

K. Ogungbenro, L. Aarons, The Cresim Project Group, The Epi-Cresim Project Group, Catherine Cornu, Patrice Nony...

European Journal of Pharmaceutical Sciences . 63 : 45-52

2014

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A Physiologically Based Pharmacokinetic Model for Clobazam and Stiripentol in Adults and Children

K. Ogungbenro, L. Aarons, The Cresim Project Group, The Epi-Cresim Project Group, Catherine Cornu, Behrouz Kassai...

Pharmaceutical Research . 32 : 144-157

2014

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A methodological framework for drug development in rare diseases

Patrice Nony, Polina Kurbatova, Agathe Bajard, Salma Malik, Charlotte Castellan, Sylvie Chabaud...

Orphanet Journal of Rare Diseases . 9 ( 164 ) : 1-10

DOI: 10.1186/s13023-014-0164-y

2014

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Recruitment in pediatric clinical research was influenced by study characteristics and pediatricians' perceptions: a multicenter survey.

Florentia Kaguelidou, Philippe Amiel, Audrey Blachier, Catalina Iliescu, Jean-Christophe Rozé, Michel Tsimaratos...

Journal of Clinical Epidemiology . 66 ( 10 ) : epub ahead of print

DOI: 10.1016/j.jclinepi.2013.04.015

2013

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Experimental designs for small randomised clinical trials: an algorithm for choice.

Catherine Cornu, Behrouz Kassai, Roland Fisch, Catherine Chiron, Corinne Alberti, Renzo Guerrini...

Orphanet Journal of Rare Diseases . 8 ( 1 ) : 48

DOI: 10.1186/1750-1172-8-48

2013

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A revisited strategy for antiepileptic drug development in children: designing an initial exploratory step

C. Chiron, Behrouz Kassai, O. Dulac, Gérard Pons, R. Nabbout

CNS Drugs . 27 : 185-95

DOI: 10.1007/s40263-012-0035-9

2013

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A European approach to clinical investigator training

Jm. Boeynaems, C. Canivet, A. Chan, Mj. Clarke, C. Cornu, E. Daemen...

Frontiers in Pharmacology . 4 : 112

DOI: 10.3389/fphar.2013.00112

2013

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L\textquoterighteffet placebo chez l\textquoterightenfant est méconnu et peu étudié

B. Kassai, H. Gheit, R. Boussageon, F. Gueyffier

La Lettre du Pharmacologue . 27 : 17--20

2013

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Information et participation active des patients à l\textquoterightaide d\textquoterightune brochure interactive lors de la prescription d\textquoterightantihypertenseurs en soins primaires

M. Keriel-Gascou, A. Badet-Phan, Ma. Le Pogam, S. Figon, L. Letrilliart, F. Gueyffier...

Santé Publique . 25 : 193--201

2013

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Physicians' knowledge and practice of lung cancer screening: a cross-sectional survey comparing general practitioners, thoracic oncologists, and pulmonologists in France

S. Couraud, N. Girard, S. Erpeldinger, François Gueyffier, G. Devouassoux, G. Llorca...

Clinical Lung Cancer . 14 : 574-80

DOI: 10.1016/j.cllc.2013.05.003

2013

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Biomarker-guided therapies in heart failure: a forum for unified strategies

M. Fiuzat, C. M. O'Connor, François Gueyffier, A. M. Mascette, N. L. Geller, A. Mebazaa...

Journal of Cardiac Failure . 19 : 592-9

DOI: 10.1016/j.cardfail.2013.05.012

2013

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Impaired baroreflex sensitivity and the risks of new-onset ambulatory hypertension, in an elderly population-based study

V. Dauphinot, M. P. Kossovsky, François Gueyffier, V. Pichot, P. Gosse, F. Roche...

International Journal of Cardiology . 168 : 4010-4

DOI: 10.1016/j.ijcard.2013.06.080

2013

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Meta-analysis of randomised trials with a continuous outcome according to baseline imbalance and availability of individual participant data

Richard Riley, Iram Kauser, Martin Bland, Lutgarde Thijs, Jan Staessen, Jiguang Wang...

Statistics in Medicine . 32 ( 16 ) : 2747-2766

DOI: 10.1002/sim.5726

2013

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Are we using blood pressure-lowering drugs appropriately? Perhaps now is the time for a change

François Gueyffier, J. Wright

Journal of human hypertension . 28 : 68-70

DOI: 10.1038/jhh.2013.79

2013

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Practical application of the charter of pharmaceutical sales visit

B. Leroy, M. Uhart, A. Lajoinie, P. Maire, M. Ducher, Laurent Bourguignon

Annales Pharmaceutiques Françaises . 70 : 348--52

DOI: 10.1016/j.pharma.2012.06.001

2013

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Statistiques et Modélisation pour les Sciences de la Santé

Equipe Biostatistiques Santé

Equipe Evaluation et Modélisation des Effets Thérapeutiques

Publications

A pyriform sinus cancer organ preservation strategy comprising induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil, followed by potentiated radiotherapy: a multicenter, retrospective study

Cardiovascular Events and Bleeding Risk Associated With Intravitreal Antivascular Endothelial Growth Factor Monoclonal Antibodies: Systematic Review and Meta-analysis

Guidelines for Managing High Blood Pressure

Multivariate meta-analysis using individual participant data

Can we identify response markers to antihypertensive drugs? First results from the Ideal Trial.

Determinants of torsades de pointes in older patients with drug-associated long QT syndrome: a case-control study

Exposure to anticholinergic and sedative drugs, risk of falls, and mortality: an elderly inpatient, multicenter cohort

Pharmacokinetic Drug Interaction Between Cyclosporine and Imatinib in Bone Marrow Transplant Children and Model-Based Reappraisal of Imatinib Drug Interaction Profile

Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children

Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial

Modeling the seasonality of Anopheles gambiae s.s. biting rates in a South Benin sanitary zone

Prostate Focal Peripheral Zone Lesions: Characterization at Multiparametric MR Imaging--Influence of a Computer-aided Diagnosis System

Spatial distribution of Toxoplasma gondii oocysts in soil in a rural area: Influence of cats and land use.

Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 2: 6-mercaptopurine and its interaction with methotrexate

Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 1: methotrexate

A physiologically based pharmacokinetic model for Valproic acid in adults and children

A Physiologically Based Pharmacokinetic Model for Clobazam and Stiripentol in Adults and Children

A methodological framework for drug development in rare diseases

Recruitment in pediatric clinical research was influenced by study characteristics and pediatricians' perceptions: a multicenter survey.

Experimental designs for small randomised clinical trials: an algorithm for choice.

A revisited strategy for antiepileptic drug development in children: designing an initial exploratory step

A European approach to clinical investigator training

L\textquoterighteffet placebo chez l\textquoterightenfant est méconnu et peu étudié

Information et participation active des patients à l\textquoterightaide d\textquoterightune brochure interactive lors de la prescription d\textquoterightantihypertenseurs en soins primaires

Physicians' knowledge and practice of lung cancer screening: a cross-sectional survey comparing general practitioners, thoracic oncologists, and pulmonologists in France

Biomarker-guided therapies in heart failure: a forum for unified strategies

Impaired baroreflex sensitivity and the risks of new-onset ambulatory hypertension, in an elderly population-based study

Meta-analysis of randomised trials with a continuous outcome according to baseline imbalance and availability of individual participant data

Are we using blood pressure-lowering drugs appropriately? Perhaps now is the time for a change

Practical application of the charter of pharmaceutical sales visit

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