It is not the strongest of the species that survives, or the most intelligent ; it is the one most capable of change
Mots clés: Plasticité phénotypique, Biologie de l'invasion, Température, Drosophila
News
https://genestogenomes.org/in-memoriam-jean-r-david-1931-2021/
Phenotypic plasticity and adaptive responses to environmental change
My research work has allowed me to explore different aspects concerning the adaptive responses of organisms to environmental changes, mainly temperature, on the insect model and especially on Drosophila through a comparative approach. I was particularly interested in phenotypic plasticity which can be defined as the ability of a genotype to produce different phenotypes according to environmental conditions. Phenotypic plasticity is a phenomenon that can be generalized to all living organisms and that can be found in all species and for a wide variety of phenotypic traits.
The main questions addressed during my research are :
How to analyze the shapes of non-linear reaction norms? Do these reaction norms present genetic variability? How do these norms evolve between populations and between species? Do these comparisons provide arguments for adaptive phenotypic plasticity?
How will environmental variability (thermal fluctuation) impact the shape of response norms? What about environmental complexity (combination of several factors)?
What is the importance of phenotypic plasticity as a response mechanism to environmental perturbations?
Drosophila suzukii: a recent biological invasion and a major economic threat
For the past few years, my research activity has focused on a project concerning a very recent biological invasion event involving a fruit crop pest, Drosophila suzukii. At the fundamental level, we were first interested in the ecological factors that explain the invasive success of this species whose biology was poorly known. We showed that French larval parasitoids were unable to control D. suzukii populations because of its very high immune resistance capacity. We also showed that this species has a very wide range of wild host plants present throughout the year and we highlighted an interesting case of self-medication in D. suzukii. Moreover, our results suggest that if D. suzukii does not really have competitors on healthy fruits, it can undergo a strong larval competition with D. melanogaster on rotten fruits on which an oviposition avoidance behavior is observed. Current projects aim to use the recent and spectacular invasion of D. suzukii to better understand the mechanisms of adaptation to a new environment, in particular the role of phenotypic plasticity. Finally, some projects have also been developed to consider new control methods against this formidable crop pest.
Ongoing projects
ANR SWING project: Genetics, plasticity and evolutionary potential of Drosophila suzukii
L’objectif général de ce projet que je porte et qui est réalisé en collaboration avec
The general objective of this project, which I lead and which is carried out in collaboration with Vincent Debat (ISyEB, MNHN), Simon Fellous et Arnaud Estoup (CBGP Montpellier) and Cristina Vieira (LBBE), is to study the evolutionary processes at play during a biological invasion with a focus on the mechanisms of adaptation. We are also interested in the evolutionary potential of the invasive species in order to predict its capacity to adapt in the short and medium term. Thus, the different components are 1) to quantify the phenotypic variation of native and invasive populations using quantitative genetic methods and the study of reaction norms; 2) to characterize, at the genomic and transcriptomic level, the genetic basis of adaptation during the invasion process by determining the relative importance of natural selection and genetic drift on the phenotypic differentiation between native and invasive populations; 3) to combine these phenotypic and molecular approaches in order to better understand which traits are associated with invasion success, and to analyze the role of transposable elements in adaptation; 4) to evaluate the agronomic consequences of the plasticity and rapid adaptation capacity of D. suzukii.
ANR CRASHPEST project : A cascade of destabilizations: combining Wolbachia and Allee effects to eradicate the insect pest Drosophila suzukii
This project led by Laurence Mouton (LBBE) in collaboration with Emmanuel Desouhant (LBBE) and Xavier Fauvergue (ISA, Sophia Antipolis) aims to develop a method of control of D. suzukii based on the manipulation of processes intrinsic to populations, the meeting and compatibility of sexual partners, combining mating disruption and inoculation of bacteria of the genus Wolbachia.
ANR DroThermal project : What makes Drosophila suzukii such an effective invader ? an integrative analyses of its thermal ecology
The objective of DroThermal, led by Hervé Colinet (ECOBIO, Rennes), is to integrate different levels of variation across different spatio-temporal scales in order to better understand the thermal responses of Drosophila suzukii and thus to better predict the persistence and dynamics of populations at both local and global levels. This project will be carried out in collaboration with Sylvain Pincebourde (IRBI) for spatial variations, Olivier Chabrerie (EDYSAN) for trophic variations and Laurence Mouton (LBBE) for the integration of host-microbe interactions.
ANR LongevitY project : Exploring the contribution of sex chromosomes to male-female differences in aging and longevity
This project led by Cristina Vieira (LBBE) is a federative project at the laboratory level because it involves researchers from the four departments of the LBBE working on different aspects of aging and on various biological models (birds and large mammals, humans, Drosophila).
The main objective of the project is to test the contribution of sex chromosomes to the sex gap longevity (SGL). The underlying hypothesis is that in species with sex chromosomes, all deleterious recessive mutations are expressed on the single X chromosome in males and may reduce their lifespan, the so-called unprotected X effect. In addition, the many transposable elements (TEs) on the Y chromosome can affect aging. The activity of TEs is normally suppressed by epigenetic regulation (DNA methylation, histone modifications and small RNAs). However, it is known that this regulation is disrupted with age. Due to the Y chromosome, more ETs can become active in aged males than in aged females, generating more somatic mutations, accelerating aging and reducing lifespan in males, the so-called Y-toxic effect. My participation in this project will focus on characterizing the toxic effects of Y in different species and populations of Drosophila.
Responsabilités
Présidente du CS INEE
Responsable du Pôle Biodiversité de la FR BioEEnViS
Responsable du DIPEE Lyon St-Etienne
Publications
Display of 1 to 30 publications on 112 in total
Contribution of variable TE content on phenotype and plasticity in Drosophila melanogaster.
Annual meeting of the Society of Molecular Biology and Evolution (SMBE) .
Conference paper
see the publicationContribution of variable TE content on phenotype and plasticity in Drosophila melanogaster.
Conférence Jacques Monod Life is plastic .
Conference paper
see the publicationContribution of variable TE content on phenotype and plasticity in Drosophila melanogaster
International congress of transposable elements .
Poster
see the publicationProjet DS2 : Drosophila suzukii « Développer des Stratégies de gestion efficaces, économiquement viables et durables »
Innovations Agronomiques . 94 : 127-140
Journal article
see the publicationModelling thermal reaction norms for development and viability in Drosophila suzukii under constant, fluctuating and field conditions
Journal of Thermal Biology . 123 : 103891
Journal article
see the publicationPoster de présentation du living lab Antharès - Réseau de living labs Solu-Biod
Lancement officiel du Programme national de recherche sur les Solutions fondées sur la Nature .
Poster
see the publicationA synthesis of biological invasion hypotheses associated with the introduction–naturalisation–invasion continuum
Oikos . 5 ( 5 ) : e09645
DOI: 10.1111/oik.09645
Journal article
see the publicationLarval density in the invasive Drosophila suzukii : Immediate and delayed effects on life‐history traits
Ecology and Evolution . 13 ( 8 ) : e10433
DOI: 10.1002/ece3.10433
Journal article
see the publicationLarval density in the invasive Drosophila suzukii : Immediate and delayed effects on life‐history traits
Ecology and Evolution . 13 ( 8 ) : 1760-1776
DOI: 10.1002/ece3.10433
Journal article
see the publicationMicrobiota-mediated competition between Drosophila species
Microbiome . 11 : 201
Journal article
see the publicationLarval density in the invasive Drosophila suzukii : Immediate and delayed effects on life‐history traits
Ecology and Evolution . 13 ( 8 ) : e10433
DOI: 10.1002/ece3.10433
Journal article
see the publicationThermal plasticity of insecticide sensitivity in an invasive pest species
SFE2 GfÖ EEF Joint meeting, International Conference on Ecological Sciences “Ecology and Evolution: New perspective and societal challenges .
Conference paper
see the publicationSterile Insect Technique: Principles, Deployment and Prospects
Extended Biocontrol . : 55-67
Book chapter
see the publicationLarval density in the invasive Drosophila suzukii : immediate and delayed effects on life-history traits
Preprint
see the publicationDifferentiation of thermal reaction norms between marginal and core populations of a northward expanding parasitoid
Preprint
see the publicationMacroecological patterns of fruit infestation rates by the invasive fly Drosophila suzukii in the wild reservoir host plant Sambucus nigra
Agricultural and Forest Entomology . 24 ( 4 ) : 548-563
DOI: 10.1111/afe.12520
Journal article
see the publicationMacroecological Patterns of Fruit Infestation Rates by the Invasive Fly Drosophila suzukii in the Reservoir Host Plant Sambucus nigra
1st International Electronic Conference on Biological Diversity, Ecology and Evolution . : 9469
Conference paper
see the publicationDetection and monitoring of Drosophila suzukii in raspberry and cherry orchards with volatile organic compounds in the USA and Europe
Scientific Reports . 11 ( 1 )
Journal article
see the publicationThe Worldwide Invasion of Drosophila suzukii Is Accompanied by a Large Increase of Transposable Element Load and a Small Number of Putatively Adaptive Insertions
Molecular Biology and Evolution . 38 ( 10 ) : 4252-4267
Journal article
see the publicationPhenotypic and Transcriptomic Responses to Stress Differ According to Population Geography in an Invasive Species
Genome Biology and Evolution . 13 ( 9 ) : evab208
DOI: 10.1093/gbe/evab208
Journal article
see the publicationGenetic Variability, Population Differentiation, and Correlations for Thermal Tolerance Indices in the Minute Wasp, Trichogramma cacoeciae
Insects . 12 ( 11 ) : 1013
Journal article
see the publicationGenomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses
Molecular Biology and Evolution . 37 ( 9 ) : 2661-2678
Journal article
see the publicationDrosophila suzukii oxidative stress response involves Jheh gene cluster but not transposable elements
Preprint
see the publicationBiological Invasion: The Influence of the Hidden Side of the (Epi)Genome
Functional Ecology . 34 ( 2 ) : 385-400
Journal article
see the publicationBiological Invasion Theories: Merging Perspectives from Population, Community and Ecosystem Scales
Biological Reviews .
Preprint
see the publicationPhenotypic plasticity in the invasive pest Drosophila suzukii: activity rhythms and gene expression in response to temperature
Journal of Experimental Biology . 222 : jeb199398
DOI: 10.1242/jeb.199398
Journal article
see the publicationPhenotypic plasticity, global change, and the speed of adaptive evolution
Current Opinion in Insect Science . 35 : 34-40
Journal article
see the publicationBack and forth Wolbachia transfers reveal efficient strains to control spotted wing drosophila populations
Journal of Applied Ecology . 55 ( 5 ) : 2408-2418
Journal article
see the publicationPlasticité phénotypique et réponses adaptatives au changement climatique
L’adaptation au changement climatique . 978-2-271-09482-7 : 95-102
Book chapter
see the publicationTransposable Element Dynamics in an Invasive Species
Congrès National des Éléments Transposables (CNET 2018) .
Conference paper
see the publication