Evolutionary Ecology

Quantitative and Evolutionary Ecology of Communities Group

Delignette-Muller Marie-Laure

Professeure des universités

VetAgro-Sup

Address: 69280 MARCY L'ÉTOILE

Tel: 33 04 72 43 27 56

Email

I am a Professor at VetAgro Sup, responsible for various modules of biostatistics at the veterinary curriculum, a module of critical reading of articles and co-leader of a module of Bayesian statistics mutualized between the three masters piloted by the LBBE. Some of my teaching documents are available on my personal web page.

My research activity is in the field of biometrics. I develop models and inference methods in the context of risk assessment in the field of health and environmental risks. My objective is to propose models/methods useful to researchers to better understand risks, and useful to managers to define risk indicators. My areas of expertise are: hierarchical models, non-linear models, dose-response models, in particular dose-response modeling of omics data, Bayesian inference.

In order to facilitate the use of the methods I develop to the largest number of people, I am involved in the development of various R packages: fitdistrplus, nlstools, DRomics.

My publications are listed exhaustively on my Google Scholar profile and my most recent papers are available on my HAL CV.

Publications

Display of 31 to 60 publications on 106 in total

Approche de Modélisation Hiérarchique pour la Description de l'Effet de la Compétition Interspécifique sur la Tolérance Chimique d'Herbacées

Vincent Baillard, Marie Laure Delignette-Muller, Cécile Sulmon, Anne‐kristel Bittebière, Cendrine Mony, Simon Devin...

SEFA 2019 Lyon .

Conference paper

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Outils d'observation des boiteries

Valentin Poulain, Luc Mounier, Marie Laure Delignette-Muller, Dorothee Ledoux

Journées Nationales des Groupements Techniques Vétérinaires (JNGTV) . : np

Poster

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Importance de la variabilité intraspécifique de la polluosensibilité pour l’évaluation du risque ecotoxicologique basée sur l’approche SSD (Species Sensitivity Distribution)

Vincent Baillard, Laurine Malardier, Marie Laure Delignette-Muller, Eva Roubeau Dumont, Arnaud Elger, Agnes Bouchez...

38ème colloque de l’Association des Diatomistes de Langue Française (ADLaF) .

Conference paper

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How to implement functional responses of migroalgae in risk assessment processing ?

F. Larras, E. Billoir, S. Schloz, Marie-Laure Delignette-Muller, M. Schmitt-Jansen

Congrès européen de la SETAC «Science and Technology for Environmental Protection» .

Conference paper

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Defining simple toxicity values (EC, BMD) is not so simple

E. Billoir, F. Larras, V. Baillard, S. Devin, M. Schmitt-Jansen, Marie-Laure Delignette-Muller

Congrès européen de la SETAC «Science and Technology for Environmental Protection» .

Poster

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Evaluation de méthodes diagnostiques en l’absence de gold standard sur la base de variables binaires et continues : intérêt de l'approche bayésienne

T. Lurier, Marie Laure Delignette-Muller, Elsa Jourdain, Florence Ayral

Journée AppliBUGS . : 38 slides

Conference paper

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Diagnosis of bovine dictyocaulosis by bronchoalveolar lavage technique: A comparative study using a Bayesian approach

T. Lurier, Marie Laure Delignette-Muller, Benoît Rannou, Christina Strube, G. Bourgoin, Marie-Anne Arcangioli

Preventive Veterinary Medicine . 154 : 124-131

DOI: 10.1016/j.prevetmed.2018.03.017

Journal article

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MOSAIC: a web-interface for statistical analyses in ecotoxicology

Sandrine Charles, Philippe Veber, Marie Laure Delignette-Muller

Environmental Science and Pollution Research . 25 ( 12 ) : 11295-11302

DOI: 10.1007/s11356-017-9809-4

Journal article

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DRomics: A Turnkey Tool to Support the Use of the Dose–Response Framework for Omics Data in Ecological Risk Assessment

Floriane Larras, Elise Billoir, Vincent Baillard, Aurélie Siberchicot, Stefan Scholz, Tesfaye Wubet...

Environmental Science and Technology . 52 ( 24 ) : 14461-14468

DOI: 10.1021/acs.est.8b04752

Journal article

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Assessment of Ozone or Not-Treated Wastewater Ecotoxicity Using Mechanism-Based and Zebrafish Embryo Bioassays

Adriana Wigh, Selim Ait-Aissa, Nicolas Creusot, Hugo Terrisse, Marie Laure Delignette-Muller, Alexandre Bergé...

Journal of Environmental Protection . 09 ( 04 ) : 325 - 346

DOI: 10.4236/jep.2018.94022

Journal article

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Response to Comment on "Robust Fit of Toxicokinetic-Toxicodynamic Models Using Prior Knowledge Contained in the Design of Survival Toxicity Tests

Marie Laure Delignette-Muller, P. Veber

Environmental Science and Technology . 51 : 8202-8203

DOI: 10.1021/acs.est.7b02548

Journal article

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Robust Fit of Toxicokinetic-Toxicodynamic Models Using Prior Knowledge Contained in the Design of Survival Toxicity Tests

Marie Laure Delignette-Muller, P. Ruiz, P. Veber

Environmental Science and Technology . 51 : 4038-4045

DOI: 10.1021/acs.est.6b05326

Journal article

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Analysis of hemocytes in Lymnaea stagnalis: Characterization and effects of repeated hemolymph collections

Paul Boisseaux, Marie Laure Delignette-Muller, Khédidja Abbaci, Hélène Thomas, Jeanne Garric

Fish and Shellfish Immunology . 57 : 116-126

DOI: 10.1016/j.fsi.2016.08.007

Journal article

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Recommendations for the analysis of hemocyte-related immunocompetent oxidative activity in the freshwater snail Lymnaea stagnalis

P. Boisseaux, P. Noury, Marie Laure Delignette-Muller, H. Thomas, J. Garric

Journal of Xenobiotics . 6 : 25-27

DOI: 10.4081/xeno.2016.6585

Journal article

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fitdistrplus : An R Package for Fitting Distributions

Marie Laure Delignette-Muller, Christophe Dutang

Journal of Statistical Software . 64 ( 4 )

DOI: 10.18637/jss.v064.i04

Journal article

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Constructing Time-Resolved Species Sensitivity Distributions Using a Hierarchical Toxico-Dynamic Model

Guillaume Kon Kam King, Marie Laure Delignette-Muller, Ben J. Kefford, Christophe Piscart, Sandrine Charles

Environmental Science and Technology . 49 ( 20 ) : 12465-12473

DOI: 10.1021/acs.est.5b02142

Journal article

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A Toolbox for Nonlinear Regression in R: The Package nistools

F. Baty, C. Ritz, Sandrine Charles, M. Brutsche, Jean-Pierre Flandrois, Marie Laure Delignette-Muller

Journal of Statistical Software . 66 : 1-21

Journal article

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MOSAIC_SSD: A new web tool for species sensitivity distribution to include censored data by maximum likelihood

Guillaume Kon Kam King, Philippe Veber, Sandrine Charles, Marie Laure Delignette-Muller

Ecotoxicology and Environmental Safety . 33 ( 9 ) : 2133 - 2139

DOI: 10.1002/etc.2644

Journal article

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Hierarchical modelling of species sensitivity distribution: development and application to the case of diatoms exposed to several herbicides

Guillaume Kon Kam King, Floriane Larras, Sandrine Charles, Marie Laure Delignette-Muller

Ecotoxicology and Environmental Safety . 114 : 212-221

DOI: 10.1016/j.ecoenv.2015.01.022

Journal article

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Statistical handling of reproduction data for exposure-response modeling

Marie Laure Delignette-Muller, Christelle Lopes, Philippe Veber, Sandrine Charles

Environmental Science and Technology . 48 : 7544-51

DOI: 10.1021/es502009r

Journal article

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Development and validation of an OECD reproductive toxicity test guideline with the pond snail Lymnaea stagnalis (Mollusca, Gastropoda)

Virginie Ducrot, Clare Askem, Didier Azam, Denise Brettschneider, Rebecca Brown, Sandrine Charles...

Regulatory Toxicology and Pharmacology . 70 ( 3 ) : 605-614

DOI: 10.1016/j.yrtph.2014.09.004

Journal article

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Modeling of Clostridium perfringens vegetative cell inactivation in beef-in-sauce products: A meta-analysis using mixed linear models

S. Jaloustre, Laurent Guillier, E. Morelli, V. Noël, Marie-Laure Delignette-Muller

International journal of food microbiology . 154 : 44--51

DOI: 10.1016/j.ijfoodmicro.2011.12.013

Journal article

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What to do with NOECS/NOELS - prohibition or innovation?

Dr Fox, Elise Billoir, S. Charles, Marie-Laure Delignette-Muller, C. Lopes

Integr Environ Assess Manag . 8 : 764--766

DOI: 10.1002/ieam.1350

Journal article

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Comparison of bioassays with different exposure time patterns: The added value of dynamic modelling in predictive ecotoxicology

Elise Billoir, Hélène Delhaye, Carole Forfait-Dubuc, Bernard Clément, Gaëlle Triffault-Bouchet, Sandrine Charles...

Ecotoxicology and Environmental Safety . 75 : 80-86

DOI: 10.1016/j.ecoenv.2011.08.006

Journal article

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Fitting a lognormal distribution to enumeration and absence/presence data

Natalie N. Commeau, Éric É. Parent, Marie Laure Delignette-Muller, Marie Cornu

International Journal of Food Microbiology . 155 ( 3 ) : 146 - 152

DOI: 10.1016/j.ijfoodmicro.2012.01.023

Journal article

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Modeling of Clostridium perfringens vegetative cell inactivation in beef-in-sauce products: A meta-analysis using mixed linear models

S. Jaloustre, Laurent Guillier, E. Morelli, V. Noël, Marie Laure Delignette-Muller

International Journal of Food Microbiology . 154 : 44-51

Journal article

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Survival data analyses in ecotoxicology: critical effect concentrations, methods and models. What should we use?

Carole Forfait-Dubuc, Sandrine Charles, Elise Billoir, Marie-Laure Delignette-Muller

Ecotoxicology . 21 : 1072--1083

DOI: 10.1007/s10646-012-0860-0

Journal article

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Bayesian modeling of Clostridium perfringens growth in beef-in-sauce products

S. Jaloustre, M. Cornu, E. Morelli, C. Noël, Marie Laure Delignette-Muller

Food Microbiology . 28 : 311-320

DOI: 10.1016/j.fm.2010.04.002

Journal article

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Bayesian modelling of daphnid responses to time-varying cadmium exposure in laboratory aquatic microcosms

Elise Billoir, Hélène Delhaye, Bernard Clément, Marie Laure Delignette-Muller, Sandrine Charles

Ecotoxicology and Environmental Safety . 74 ( 4 ) : 693-702

DOI: 10.1016/j.ecoenv.2010.10.023

Journal article

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The importance of incorporating age and sex when backcalculating length in bullhead Cottus gobio

J. Kielbassa, Sandrine Charles, Marie Laure Delignette-Muller

Journal of Fish Biology . 78 : 1492-1507

DOI: 10.1111/j.1095-8649.2011.02956.x

Journal article

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