Statistics and Modelling for Health Sciences

The precision–recall curve overcame the optimism of the receiver operating characteristic curve in rare diseases

Brice Ozenne, Fabien Subtil, Delphine Maucort-Boulch

Journal of Clinical Epidemiology . 68 : 855-9

2015

Journal article

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Spatially regularized mixture model for lesion segmentation with application to stroke patients

B. Ozenne, Fabien Subtil, L. Ostergaard, Delphine Maucort-Boulch

Biostatistics . 16 ( 3 ) : 580-595

DOI: 10.1093/biostatistics/kxv004

2015

Journal article

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Management of adolescents with very poorly controlled type 1 diabetes by nurses: a parallel group randomized controlled trial

B. Kassai, Muriel Rabilloud, D. Bernoux, C. Michal, B. Riche, T. Ginhoux...

Trials . 16 ( 1 ) : 399

DOI: 10.1186/s13063-015-0923-7

2015

Journal article

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Comparison of two next-generation sequencing kits for diagnosis of epileptic disorders with a user-friendly tool for displaying gene coverage, DeCovA

S. Dimassi, T. Simonet, A. Labalme, N. Boutry-Kryza, Amandine Campan-Fournier, R. Lamy...

Applied & Translational Genomics . 7 : 19-25

DOI: 10.1016/j.atg.2015.10.001

2015

Journal article

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Accuracy of different equations in estimating GFR in pediatric kidney transplant recipients

V. de Souza, P. Cochat, Muriel Rabilloud, L. Selistre, M. Wagner, A. Hadj-Aissa...

Clinical Journal of the American Society of Nephrology . 10 ( 3 ) : 463-70

DOI: 10.2215/CJN.06300614

2015

Journal article

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Clinical profile of patients with ATP1A3 mutations in Alternating Hemiplegia of Childhood-a study of 155 patients

E. Panagiotakaki, E. de Grandis, M. Stagnaro, E. L. Heinzen, C. Fons, S. Sisodiya...

Orphanet Journal of Rare Diseases . 10 : 123

DOI: 10.1186/s13023-015-0335-5

2015

Journal article

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Influence of renal function estimation on pharmacokinetic modeling of vancomycin in elderly patients

A. Glatard, Laurent Bourguignon, R. W. Jelliffe, P. Maire, M. N. Neely, Sylvain Goutelle

Antimicrobial Agents and Chemotherapy . 59 ( 6 ) : 2986-94

DOI: 10.1128/AAC.04132-14

2015

Journal article

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CSF IgA NMDAR antibodies are potential biomarkers for teratomas in anti-NMDAR encephalitis

V. Desestret, A. Chefdeville, A. Viaccoz, C. Bost, F. Ducray, G. Picard...

Neurology Neuroimmunology & Neuroinflammation . 2 ( 6 ) : e166

DOI: 10.1212/NXI.0000000000000166

2015

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An 18F-FDG-PET maximum standardized uptake value > 10 represents a novel valid marker for discerning Richter’s Syndrome

Anne-Sophie Michallet, Pierre Sesques, Kari Rabe, Emmanuel Itti, Jérémy Tordot, Christelle Tychyj-Pinel...

Leukemia & lymphoma . 57 ( 6 ) : 1474-1477

DOI: 10.3109/10428194.2015.1099643

2015

Journal article

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Sequential combination of gemcitabine, vinorelbine, pegylated liposomal doxorubicin and Brentuximab as a bridge regimen to transplant in relapsed or refractory Hodgkin lymphoma

As. Michallet, Y. Guillermin, B. Deau, L. Lebras, S. Harel, S. Amorin...

Haematologica . 100 ( 7 ) : e269-e271

DOI: 10.3324/haematol.2015.124784

2015

Journal article

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A Prediction Model of Drug Exposure in Cirrhotic Patients According to Child-Pugh Classification

J. Steelandt, E. Jean-Bart, Sylvain Goutelle, M. Tod

Clinical Pharmacokinetics . 54 : 1245-58

DOI: 10.1007/s40262-015-0288-9

2015

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Exposure of Staphylococcus aureus to subinhibitory concentrations of β-lactam antibiotics induces heterogeneous vancomycin-intermediate Staphylococcus aureus

Mélanie Roch, Perrine Clair, Adriana Renzoni, Marie-Elisabeth Reverdy, Olivier Dauwalder, Michèle Bes...

Antimicrobial Agents and Chemotherapy . 58 ( 9 ) : 5306-5314

DOI: 10.1128/AAC.02574-14

2014

Journal article

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Impact of Scedosporium apiospermum complex seroprevalence in patients with cystic fibrosis

Perrine Parize, Sandrine Nail-Billaud, Anne-Lise Bienvenu, Stéphanie Bourdy, Marie Le Pogam, Philippe Reix...

Journal of Cystic Fibrosis . 13 ( 6 ) : 667-673

DOI: 10.1016/j.jcf.2014.01.011

2014

Journal article

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Consistency of safety profile of new oral anticoagulants in patients with renal failure

Jean-Christophe Lega, L. Bertoletti, C. Gremillet, C. Boissier, P. Mismetti, S. Laporte

Journal of Thrombosis and Haemostasis . 12 ( 2 ) : 337-43

DOI: 10.1111/jth.12486

2014

Journal article

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Characteristics, prognosis, and outcomes of cutaneous ischemia and gangrene in systemic necrotizing vasculitides: a retrospective multicenter study

Jean-Christophe Lega, Raphaèle Seror, Thomas Fassier, Olivier Aumaître, Isabelle Quere, Jacques Pourrat...

Seminars in Arthritis and Rheumatism . 43 ( 5 ) : 681--688

DOI: 10.1016/j.semarthrit.2013.09.001

2014

Journal article

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The clinical phenotype associated with myositis-specific and associated autoantibodies: a meta-analysis revisiting the so-called antisynthetase syndrome

Jean-Christophe Lega, N. Fabien, Q. Reynaud, I. Durieu, S. Durupt, M. Dutertre...

Autoimmunity Reviews . 13 : 883-91

2014

Journal article

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The clinical phenotype associated with myositis-specific and associated autoantibodies: a meta-analysis revisiting the so-called antisynthetase syndrome

Jean-Christophe Lega, Nicole Fabien, Quitterie Reynaud, Isabelle Durieu, Stéphane Durupt, Marine Dutertre...

Autoimmunity Reviews . 13 ( 9 ) : 883-891

DOI: 10.1016/j.autrev.2014.03.004

2014

Journal article

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Risk of venous and arterial thrombosis according to type of antiphospholipid antibodies in adults without systemic lupus erythematosus: a systematic review and meta-analysis

Q. Reynaud, Jean-Christophe Lega, P. Mismetti, C. Chapelle, D. Wahl, P. Cathebras...

Autoimmunity Reviews . 13 : 595-608

2014

Journal article

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Consistency of Safety and Efficacy of New Oral Anticoagulants across Subgroups of Patients with Atrial Fibrillation

Jean-Christophe Lega, L. Bertoletti, C. Gremillet, C. Chapelle, P. Mismetti, M. Cucherat...

PLoS ONE . 9 ( 3 ) : e91398

DOI: 10.1371/journal.pone.0091398

2014

Journal article

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Mutations in CECR1 associated with a neutrophil signature in peripheral blood

Alexandre Belot, Evangeline Wassmer, Marinka Twilt, Jean-Christophe Lega, Leo Ah Zeef, Anthony Oojageer...

Pediatric Rheumatology . 12 : 44

DOI: 10.1186/1546-0096-12-44

2014

Journal article

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Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial

Julien Taieb, Josep Tabernero, Enrico Mini, Fabien Subtil, Gunnar Folprecht, Jean-Luc van Laethem...

Lancet Oncology . 15 ( 8 ) : 862-873

DOI: 10.1016/S1470-2045(14)70227-X

2014

Journal article

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Homozygous MTTP and APOB mutations may lead to hepatic steatosis and fibrosis despite metabolic differences in congenital hypocholesterolemia

M. Di Filippo, Philippe Moulin, Pascal Roy, M. E. Samson-Bouma, S. Collardeau-Frachon, S. Chebel-Dumont...

Journal of Hepatology . 61 ( 4 ) : 891-902

DOI: 10.1016/j.jhep.2014.05.023

2014

Journal article

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A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Test Efficacy and Safety of Magnetic Resonance Imaging-Based Thrombolysis in Wake-up Stroke (WAKE-UP)

Götz Thomalla, Jochen Fiebach, Leif Østergaard, Salvador Pedraza, Vincent Thijs, Norbert Nighoghossian...

International Journal of Stroke . 9 ( 6 ) : 829-836

DOI: 10.1111/ijs.12011

2014

Journal article

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Lack of Correlation of BTNL2 Polymorphism and Cancer Risk in Sarcoidosis. BTNL2 and Cancer Risk in Sarcoidosis

M. Gaillot-Drevon, A. Calender, Jy. Blay, D. Valeyre, D. Israel-Biet, Pascal Roy...

Sarcoidosis vasculitis and diffuse lung diseases . 31 : 136-141

2014

Journal article

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On a measure of information gain for regression models in survival analysis

D. Maucort-Boulch, Pascal Roy, J. Stare

Journal of Applied Statistics . 41 : 2696-2708

2014

Journal article

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Pelvic-floor muscle rehabilitation in erectile dysfunction and premature ejaculation

P. Lavoisier, Pascal Roy, E. Dantony, A. Watrelot, J. Ruggeri, S. Dumoulin

Physical Therapy . 94 ( 12 ) : 1731-43

DOI: 10.2522/ptj.20130354

2014

Journal article

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Tranexamic acid for epistaxis in hereditary hemorrhagic telangiectasia patients: a European cross-over controlled trial in a rare disease

S. Gaillard, S. Dupuis-Girod, F. Boutitie, S. Riviere, S. Moriniere, P. Y. Hatron...

Journal of Thrombosis and Haemostasis . 12 : 1494-502

DOI: 10.1111/jth.12654

2014

Journal article

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Estimating the optimal threshold for a diagnostic biomarker in case of complex biomarker distributions

Fabien Subtil, Muriel Rabilloud

BMC Medical Informatics and Decision Making . 14 : 53

DOI: 10.1186/1472-6947-14-53

2014

Journal article

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Mortality and profiles of community-dwelling fallers. Results from the EPIDOS cohort

S. Bailly, J. Haesebaert, E. Decullier, P. Dargent-Molina, Cédric Annweiler, O. Beauchet...

Maturitas . 79 : 334-9

DOI: 10.1016/j.maturitas.2014.07.017

2014

Journal article

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Real-time Detection of Gastric Insufflation Related to Facemask Pressure-controlled Ventilation Using Ultrasonography of the Antrum and Epigastric Auscultation in Nonparalyzed Patients. A Prospective, Randomized, Double-blind Study

L. Bouvet, Ml. Albert, C. Augris, E. Boselli, René Ecochard, Muriel Rabilloud...

Anesthesiology . 120 : 326-334

DOI: 10.1097/ALN.0000000000000094

2014

Journal article

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Statistics and Modelling for Health Sciences

Biostatistics Health Group

Evaluation and Modeling with the Therapeutic Effects Group

Publications

The precision–recall curve overcame the optimism of the receiver operating characteristic curve in rare diseases

Spatially regularized mixture model for lesion segmentation with application to stroke patients

Management of adolescents with very poorly controlled type 1 diabetes by nurses: a parallel group randomized controlled trial

Comparison of two next-generation sequencing kits for diagnosis of epileptic disorders with a user-friendly tool for displaying gene coverage, DeCovA

Accuracy of different equations in estimating GFR in pediatric kidney transplant recipients

Clinical profile of patients with ATP1A3 mutations in Alternating Hemiplegia of Childhood-a study of 155 patients

Influence of renal function estimation on pharmacokinetic modeling of vancomycin in elderly patients

CSF IgA NMDAR antibodies are potential biomarkers for teratomas in anti-NMDAR encephalitis

An 18F-FDG-PET maximum standardized uptake value > 10 represents a novel valid marker for discerning Richter’s Syndrome

Sequential combination of gemcitabine, vinorelbine, pegylated liposomal doxorubicin and Brentuximab as a bridge regimen to transplant in relapsed or refractory Hodgkin lymphoma

A Prediction Model of Drug Exposure in Cirrhotic Patients According to Child-Pugh Classification

Exposure of Staphylococcus aureus to subinhibitory concentrations of β-lactam antibiotics induces heterogeneous vancomycin-intermediate Staphylococcus aureus

Impact of Scedosporium apiospermum complex seroprevalence in patients with cystic fibrosis

Consistency of safety profile of new oral anticoagulants in patients with renal failure

Characteristics, prognosis, and outcomes of cutaneous ischemia and gangrene in systemic necrotizing vasculitides: a retrospective multicenter study

The clinical phenotype associated with myositis-specific and associated autoantibodies: a meta-analysis revisiting the so-called antisynthetase syndrome

The clinical phenotype associated with myositis-specific and associated autoantibodies: a meta-analysis revisiting the so-called antisynthetase syndrome

Risk of venous and arterial thrombosis according to type of antiphospholipid antibodies in adults without systemic lupus erythematosus: a systematic review and meta-analysis

Consistency of Safety and Efficacy of New Oral Anticoagulants across Subgroups of Patients with Atrial Fibrillation

Mutations in CECR1 associated with a neutrophil signature in peripheral blood

Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial

Homozygous MTTP and APOB mutations may lead to hepatic steatosis and fibrosis despite metabolic differences in congenital hypocholesterolemia

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Test Efficacy and Safety of Magnetic Resonance Imaging-Based Thrombolysis in Wake-up Stroke (WAKE-UP)

Lack of Correlation of BTNL2 Polymorphism and Cancer Risk in Sarcoidosis. BTNL2 and Cancer Risk in Sarcoidosis

On a measure of information gain for regression models in survival analysis

Pelvic-floor muscle rehabilitation in erectile dysfunction and premature ejaculation

Tranexamic acid for epistaxis in hereditary hemorrhagic telangiectasia patients: a European cross-over controlled trial in a rare disease

Estimating the optimal threshold for a diagnostic biomarker in case of complex biomarker distributions

Mortality and profiles of community-dwelling fallers. Results from the EPIDOS cohort

Real-time Detection of Gastric Insufflation Related to Facemask Pressure-controlled Ventilation Using Ultrasonography of the Antrum and Epigastric Auscultation in Nonparalyzed Patients. A Prospective, Randomized, Double-blind Study

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