Statistics and Modelling for Health Sciences

Moderate intake of docosahexaenoic acid raises plasma and platelet vitamin E levels in cystic fibrosis patients

Evelyne Véricel, Stéphane Mazur, Romain Colas, Véronique Delaup, Catherine Calzada, Philippe Reix...

Prostaglandins, Leukotrienes and Essential Fatty Acids . 115 : 41 - 47

DOI: 10.1016/j.plefa.2016.10.008

2016

Journal article

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Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173-activating mutations in 3 children

Marie-Louise Frémond, Mathieu Paul Rodero, Nadia Jeremiah, Alexandre Belot, Eric Jeziorski, Darragh Duffy...

Journal of Allergy and Clinical Immunology . 138 ( 6 ) : 1752-1755

DOI: 10.1016/j.jaci.2016.07.015

2016

Journal article

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Is the raised volume rapid thoracic compression technique ready for use in clinical trials in infants with cystic fibrosis?

Stefan Matecki, Lisa Kent, Kris de Boeck, Muriel Le Bourgeois, Stefan Zielen, Cesare Braggion...

Journal of Cystic Fibrosis . 15 ( 1 ) : 10 - 20

DOI: 10.1016/j.jcf.2015.03.015

2016

Journal article

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Heterogeneous clinical spectrum of anti-SRP myositis and importance of the methods of detection of anti-SRP autoantibodies: a multicentric study

Cécile Picard, Thierry Vincent, Jean-Christophe Lega, Sophie Hue, Françoise Fortenfant, Daniel Lakomy...

Immunologic Research . 64 ( 3 ) : 677-686

DOI: 10.1007/s12026-015-8774-6

2016

Journal article

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Tocilizumab in the treatment of mixed connective tissue disease and overlap syndrome in children

Natalia Cabrera, Agnes Duquesne, Marine Desjonquères, Jean-Paul Larbre, Jean-Christophe Lega, Nicole Fabien...

RMD Open : Rheumatic & Musculoskeletal Diseases . 2 ( 2 ) : e000271

DOI: 10.1136/rmdopen-2016-000271

2016

Journal article

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Effect of Cyclosporine in Nonshockable Out-of-Hospital Cardiac Arrest: The CYRUS Randomized Clinical Trial

Laurent Argaud, M. Cour, P. Y. Dubien, F. Giraud, C. Jossan, Benjamin Riche...

JAMA Cardiology . 1 ( 5 ) : 557-65

DOI: 10.1001/jamacardio.2016.1701

2016

Journal article

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Partial validation of a French version of the ADHD-rating scale IV on a French population of children with ADHD and epilepsy. Factorial structure, reliability, and responsiveness

Catherine Mercier, S. Roche, Sophie Gaillard, Behrouz Kassai, A. Arzimanoglou, V. Herbillon...

Epilepsy & Behavior . 58 : 1-6

DOI: 10.1016/j.yebeh.2016.02.016

2016

Journal article

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Efficacy of naloxone in reducing postictal central respiratory dysfunction in patients with epilepsy: study protocol for a double- blind, randomized, placebo-controlled trial

Sylvain Rheims, Luc Valton, Véronique Michel, Louis Maillard, Vincent Navarro, Philippe Convers...

Trials . 17 : 529

DOI: 10.1186/s13063-016-1653-1

2016

Journal article

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The Net Chance of a Longer Survival as a Patient-Oriented Measure of Treatment Benefit in Randomized Clinical Trials

Julien Péron, Pascal Roy, B. Ozenne, L. Roche, M. Buyse

JAMA oncology . 2 : 901-905

DOI: 10.1001/jamaoncol.2015.6359

2016

Journal article

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Growth curves for congenital adrenal hyperplasia from a national retrospective cohort

P. Bretones, B. Riche, E. Pichot, M. David, Pascal Roy, V. Tardy...

Journal of pediatric endocrinology & metabolism . 29 : 1379-1388

DOI: 10.1515/jpem-2016-0156

2016

Journal article

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Kendrick's extrication device and unstable pelvic fractures: Should a trochanteric belt be added? A cadaveric study

Floran A Reynard, Alexandros N Flaris, Eric R Simms, Olivier Rouviere, Pascal Roy, Nicolas J Prat...

Injury . 47 ( 3 ) : pp. 711-716

DOI: 10.1016/j.injury.2016.01.028

2016

Journal article

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An assessment of the benefit-risk balance of FOLFIRINOX in metastatic pancreatic adenocarcinoma

Julien Péron, Pascal Roy, T. Conroy, Françoise Desseigne, M. Ychou, S. Gourgou-Bourgade...

Oncotarget . 7 : 82953-28960

DOI: 10.18632/oncotarget.12761

2016

Journal article

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Familial vs. sporadic sarcoidosis: BTNL2 polymorphisms, clinical presentations, and outcomes in a French cohort

Yves Pacheco, Alain Calender, Dominique Israël-Biet, Pascal Roy, Serge Lebecque, Vincent Cottin...

Orphanet Journal of Rare Diseases . 11 ( 1 ) : np

DOI: 10.1186/s13023-016-0546-4

2016

Journal article

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Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study

Charles R G Guttmann, Matthieu Rousset, Jean-Amédée Roch, Salem Hannoun, Françoise Durand-Dubief, Boubakeur Belaroussi...

Multiple Sclerosis Journal . 22 ( 6 ) : 761 - 769

DOI: 10.1177/1352458515600247

2016

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Introduction of a paediatric anaesthesia comic information leaflet reduced preoperative anxiety in children

B. Kassai, Muriel Rabilloud, E. Dantony, S. Grousson, O. Revol, S. Malik...

British Journal of Anaesthesia . 117 : 95-102

DOI: 10.1093/bja/aew154

2016

Journal article

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Accuracy of several maternal seric markers for predicting histological chorioamnionitis after preterm premature rupture of membranes: a prospective and multicentric study

J. Caloone, Muriel Rabilloud, F. Boutitie, A. Traverse-Glehen, F. Allias-Montmayeur, L. Denis...

European Journal of Obstetrics & Gynecology and Reproductive Biology . 205 : 133-40

DOI: 10.1016/j.ejogrb.2016.08.022

2016

Journal article

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Comparison of the Schwartz and CKD-EPI Equations for Estimating Glomerular Filtration Rate in Children, Adolescents, and Adults: A Retrospective Cross-Sectional Study

L. Selistre, Muriel Rabilloud, P. Cochat, V. de Souza, J. Iwaz, S. Lemoine...

PLoS Medicine . 13 : e1001979

DOI: 10.1371/journal.pmed.1001979

2016

Journal article

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Placental histological lesions in fetal and neonatal alloimmune thrombocytopenia: A retrospective cohort study of 21 cases

E. Dubruc, F. Lebreton, C. Giannoli, Muriel Rabilloud, C. Huissoud, M. Devouassoux-Shisheboran...

Placenta . 48 : 104-109

DOI: 10.1016/j.placenta.2016.10.009

2016

Journal article

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Early diagnosis of gestational trophoblastic neoplasia based on trajectory classification with compartment modeling

C. Burny, Muriel Rabilloud, F. Golfier, J. Massardier, T. Hajri, A. M. Schott...

BMC Medical Research Methodology . 16 : 3

DOI: 10.1186/s12874-015-0106-y

2016

Journal article

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Reduced bone volumetric density and weak correlation between infection and bone markers in cystic fibrosis adult patients

D. Gensburger, S. Boutroy, R. Chapurlat, R. Nove-Josserand, S. Roche, Muriel Rabilloud...

Osteoporosis International . 27 : 2803-13

DOI: 10.1007/s00198-016-3612-9

2016

Journal article

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Prone position and VAP incidence in the PROSEVA trial: attention to the causal question when interpreting competing risk analysis-response to comments by Ranzani et al.

Muriel Rabilloud, C. Guérin

Intensive Care Medicine . 42 : 2121-2122

DOI: 10.1007/s00134-016-4548-4

2016

Journal article

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Quality of qualitative studies centred on patients in family practice: a systematic review

Benedicte Eschalier, Stéphane Descamps, Bruno Pereira, Hélène Vaillant-Roussel, Guillaume Girard, Stéphane Boisgard...

Family Practice . 33 ( 6 ) : 580 - 587

DOI: 10.1093/fampra/cmw095

2016

Journal article

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Référentiel ECRIN pour la conformité aux bonnes pratiques de gestion des données des essais cliniques multinationaux

Catherine Cornu, Anne Donche, Carine Coffre, Amélie Le Gouge, Boulkedid Rym, Isabelle Vaugier...

Thérapie .

DOI: 10.2515/therapie/2015042

2016

Journal article

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Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers

L. Gabriel, M. Tod, Sylvain Goutelle

Clinical Pharmacokinetics . 55 : 977-990

DOI: 10.1007/s40262-016-0371-x

2016

Journal article

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A bench evaluation of fraction of oxygen in air delivery and tidal volume accuracy in home care ventilators available for hospital use

L. Baboi, Fabien Subtil, C. Guerin

Journal of Thoracic Disease . 8 ( 12 ) : 3639-3647

DOI: 10.21037/jtd.2016.12.64

2016

Journal article

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Le médecin généraliste face à la prise en charge de « l’allergie au médicament » : un éclairage sur la pratique actuelle en région Rhône-Alpes, et perspectives d’amélioration

V.-A. Huynh, E. Lungoci, Audrey Nosbaum, Florence Hacard, F. Subtil, Jean-François Nicolas...

Revue francaise d'allergologie . 56 ( 5 ) : 401-406

DOI: 10.1016/j.reval.2016.02.007

2016

Journal article

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kmlShape: An Efficient Method to Cluster Longitudinal Data (Time-Series) According to Their Shapes

Christophe Genolini, René Ecochard, Mamoun Benghezal, Driss Tarak, Sandrine Andrieu, Fabien Subtil

PLoS ONE . 11 ( 6 )

DOI: 10.1371/journal.pone.0150738

2016

Journal article

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Accurately Achieving Target Busulfan Exposure in Children and Adolescents With Very Limited Sampling and the BestDose Software

M. Neely, M. Philippe, T. Rushing, X. Fu, M. van Guilder, D. Bayard...

Therapeutic Drug Monitoring . 38 : 332-342

DOI: 10.1097/FTD.0000000000000276

2016

Journal article

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Should busulfan therapeutic range be narrowed in pediatrics? Experience from a large cohort of hematopoietic stem cell transplant children

M. Philippe, Sylvain Goutelle, J. Guitton, X. Fonrose, C. Bergeron, Pascal Girard...

Bone Marrow Transplantation . 51 : 72-78

DOI: 10.1038/bmt.2015.218

2016

Journal article

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Mathematical modeling and systems pharmacology of tuberculosis: Isoniazid as a case study

L. Lalande, Laurent Bourguignon, P. Maire, Sylvain Goutelle

Journal of Theoretical Biology . 399 : 43-52

DOI: 10.1016/j.jtbi.2016.03.038

2016

Journal article

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Statistics and Modelling for Health Sciences

Biostatistics Health Group

Evaluation and Modeling with the Therapeutic Effects Group

Publications

Moderate intake of docosahexaenoic acid raises plasma and platelet vitamin E levels in cystic fibrosis patients

Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173-activating mutations in 3 children

Is the raised volume rapid thoracic compression technique ready for use in clinical trials in infants with cystic fibrosis?

Heterogeneous clinical spectrum of anti-SRP myositis and importance of the methods of detection of anti-SRP autoantibodies: a multicentric study

Tocilizumab in the treatment of mixed connective tissue disease and overlap syndrome in children

Effect of Cyclosporine in Nonshockable Out-of-Hospital Cardiac Arrest: The CYRUS Randomized Clinical Trial

Partial validation of a French version of the ADHD-rating scale IV on a French population of children with ADHD and epilepsy. Factorial structure, reliability, and responsiveness

Efficacy of naloxone in reducing postictal central respiratory dysfunction in patients with epilepsy: study protocol for a double- blind, randomized, placebo-controlled trial

The Net Chance of a Longer Survival as a Patient-Oriented Measure of Treatment Benefit in Randomized Clinical Trials

Growth curves for congenital adrenal hyperplasia from a national retrospective cohort

Kendrick's extrication device and unstable pelvic fractures: Should a trochanteric belt be added? A cadaveric study

An assessment of the benefit-risk balance of FOLFIRINOX in metastatic pancreatic adenocarcinoma

Familial vs. sporadic sarcoidosis: BTNL2 polymorphisms, clinical presentations, and outcomes in a French cohort

Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study

Introduction of a paediatric anaesthesia comic information leaflet reduced preoperative anxiety in children

Accuracy of several maternal seric markers for predicting histological chorioamnionitis after preterm premature rupture of membranes: a prospective and multicentric study

Comparison of the Schwartz and CKD-EPI Equations for Estimating Glomerular Filtration Rate in Children, Adolescents, and Adults: A Retrospective Cross-Sectional Study

Placental histological lesions in fetal and neonatal alloimmune thrombocytopenia: A retrospective cohort study of 21 cases

Early diagnosis of gestational trophoblastic neoplasia based on trajectory classification with compartment modeling

Reduced bone volumetric density and weak correlation between infection and bone markers in cystic fibrosis adult patients

Prone position and VAP incidence in the PROSEVA trial: attention to the causal question when interpreting competing risk analysis-response to comments by Ranzani et al.

Quality of qualitative studies centred on patients in family practice: a systematic review

Référentiel ECRIN pour la conformité aux bonnes pratiques de gestion des données des essais cliniques multinationaux

Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers

A bench evaluation of fraction of oxygen in air delivery and tidal volume accuracy in home care ventilators available for hospital use

Le médecin généraliste face à la prise en charge de « l’allergie au médicament » : un éclairage sur la pratique actuelle en région Rhône-Alpes, et perspectives d’amélioration

kmlShape: An Efficient Method to Cluster Longitudinal Data (Time-Series) According to Their Shapes

Accurately Achieving Target Busulfan Exposure in Children and Adolescents With Very Limited Sampling and the BestDose Software

Should busulfan therapeutic range be narrowed in pediatrics? Experience from a large cohort of hematopoietic stem cell transplant children

Mathematical modeling and systems pharmacology of tuberculosis: Isoniazid as a case study

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