Statistics and Modelling for Health Sciences

Effects of socioeconomic status on excess mortality in patients with multiple sclerosis in France: A retrospective observational cohort study

Sarah Wilson, Floriane Calocer, Fabien Rollot, Mathieu Fauvernier, Laurent Remontet, Laure Tron...

The Lancet Regional Health - Europe . 24 : 100542

DOI: 10.1016/j.lanepe.2022.100542

2023

Journal article

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Influence of socio-economic status on excess mortality of multiple sclerosis

Sharon A. Wilson, F. Calocer, F. Rollot, M. Fauvernier, L Remontet, L Tron...

Multiple Sclerosis Journal . 28 ( 3_SUPPL ) : 456-457

2023

Journal article

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L’aspirine a-t-elle une place dans la prévention cardiovasculaire primaire par la polypill ? Étude de simulation sur une population virtuelle réaliste

Mor Fall, Guillaume Grenet, Hai-Ha Le, Behrouz Kassaï, Jean-Christophe Lega, Rémy Boussageon...

Therapies . 78 ( 6 ) : 667-678

DOI: 10.1016/j.therap.2023.01.011

2023

Journal article

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Association between immune‐related adverse events and prognosis in patients treated with immune checkpoint inhibitors in melanoma: A surrogacy analysis

Romain Euvrard, Marie Robert, Sabine Mainbourg, Stéphane Dalle, Jean‐christophe Lega

Fundamental & Clinical Pharmacology . 38 ( 2 ) : 369-379

DOI: 10.1111/fcp.12966

2023

Journal article

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Heart and systemic sclerosis—findings from a national cohort study

Alexis Guédon, Fabrice Carrat, Luc Mouthon, David Launay, Benjamin Chaigne, Grégory Pugnet...

Rheumatology .

DOI: 10.1093/rheumatology/kead599

2023

Journal article

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Heart and systemic sclerosis—findings from a national cohort study

Alexis Guédon, Fabrice Carrat, Luc Mouthon, David Launay, Benjamin Chaigne, Grégory Pugnet...

Rheumatology .

DOI: 10.1093/rheumatology/kead599

2023

Journal article

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Incidence of infections in patients with psoriatic arthritis and axial spondyloarthritis treated with biological or targeted disease-modifying agents: a systematic review and meta-analysis of randomised controlled trials, open-label studies and observatio

Melanie Aureal, Milene Seauve, Soline Laplane, Jean-Christophe Lega, Natalia Cabrera, Fabienne Coury

RMD Open . 9 ( 3 ) : e003064

DOI: 10.1136/rmdopen-2023-003064

2023

Journal article

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Circulating microRNAs improve bacterial infection diagnosis and overall survival prediction in acute decompensation of liver cirrhosis

Yasmina Chouik, Fanny Lebossé, Marie-Laure Plissonnier, Jean-Christophe Lega, Pierre Pradat, Teresa Antonini...

iScience . 26 ( 8 ) : 107427

DOI: 10.1016/j.isci.2023.107427

2023

Journal article

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Platelet count threshold for hemorrhage in patients with immune thrombocytopenia treated with antiplatelet agents.

Natasha Ollier, Marie-Léa Piel-Julian, Matthieu Mahevas, Jean-François Viallard, Thibault Comont, Stephane Cheze...

Blood .

DOI: 10.1182/blood.2023020311

2023

Journal article

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Patients’ perceptions on clinical trials outcomes in pulmonary arterial hypertension therapy

Vicky Mai, Camille Gosselin, Élodie Tremblay, Gabrielle Rompré, Annie Christine Lajoie, Jason Weatherald...

Thorax . 78 ( 7 ) : 721-725

DOI: 10.1136/thorax-2022-219490

2023

Journal article

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Circulating microRNAs improve bacterial infection diagnosis and overall survival prediction in acute decompensation of liver cirrhosis

Yasmina Chouik, Fanny Lebossé, Marie‐laure Plissonnier, Jean-Christophe Lega, Pierre Pradat, Teresa Antonini...

iScience . 26 ( 8 ) : 107427

DOI: 10.1016/j.isci.2023.107427

2023

Journal article

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Treatment strategy for acquired pure red cell aplasia: a systematic review and meta-analysis

Hervé Lobbes, Jean-Christophe Lega, Guillaume Le Guenno, Marc Ruivard, Sabine Mainbourg

Blood Advances . 7 ( 21 ) : 6451-6465

DOI: 10.1182/bloodadvances.2023010587

2023

Journal article

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Platelet count threshold for hemorrhage in patients with immune thrombocytopenia treated with antiplatelet agents

Natasha Ollier, Marie-Léa Piel-Julian, Matthieu Mahévas, Jean-François Viallard, Thibault Comont, Stéphane Chèze...

Blood . 142 ( 12 ) : 1099-1101

DOI: 10.1182/blood.2023020311

2023

Journal article

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Immune thrombocytopenia and pregnancy: an exposed/nonexposed cohort study

Stéphanie Guillet, Valentine Loustau, Emmanuelle Boutin, Anissa Zarour, Thibault Comont, Odile Souchaud-Debouverie...

Blood . 141 ( 1 ) : 11-21

DOI: 10.1182/blood.2022017277

2023

Journal article

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AUC-based monitoring and model-informed precision dosing of vancomycin in critically ill patients: why and how?

Sylvain Goutelle, Florent Wallet, Yann Thoma, Jean-Rémi Peclard, Laurent Bourguignon, Sabine Cohen...

Anaesthesia Critical Care & Pain Medicine . 42 ( 6 ) : 101286

DOI: 10.1016/j.accpm.2023.101286

2023

Journal article

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Population Pharmacokinetics of Vancomycin in Patients Receiving Hemodialysis in a Malian and a French Center and Simulation of the Optimal Loading Dose

Balla Coulibaly, Pascal Maire, Jêrome Guitton, Solenne Pelletier, Moustapha Tangara, Gilles Aulagner...

Therapeutic Drug Monitoring . 45 ( 5 ) : 637-643

DOI: 10.1097/FTD.0000000000001065

2023

Journal article

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Evaluation of Limited Sampling Strategies for Bayesian Estimation of Daptomycin Area Under the Concentration–Time Curve: A Short Communication

Vianney Tuloup, Aurélien Millet, Alessandra Taricco, François Parant, Tristan Ferry, Sylvain Goutelle

Therapeutic Drug Monitoring . 45 ( 4 ) : 562-565

DOI: 10.1097/FTD.0000000000001070

2023

Journal article

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From Personalized to Precision Medicine in Oncology: A Model-Based Dosing Approach to Optimize Achievement of Imatinib Target Exposure

Sylvain Goutelle, Monia Guidi, Verena Gotta, Chantal Csajka, Thierry Buclin, Nicolas Widmer

Pharmaceutics . 15 ( 4 ) : 1081

DOI: 10.3390/pharmaceutics15041081

2023

Journal article

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Suboptimal exposure to fluconazole in critically ill patients: Pharmacokinetic analysis and determinants

A.L. Bienvenu, P. Pradat, E. Matusik, V. Piriou, T. Rimmelé, F. Parant...

Infectious Diseases Now . 53 ( 2 ) : 104630

DOI: 10.1016/j.idnow.2022.10.002

2023

Journal article

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Evaluation of Renal Impairment Influence on Metabolic Drug Clearance using a Modelling Approach

Vianney Tuloup, Sylvain Goutelle, Michel Tod, Laurent Bourguignon

Clinical Pharmacokinetics . 62 ( 2 ) : 307-319

DOI: 10.1007/s40262-022-01205-3

2023

Journal article

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Granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients presenting sepsis-induced immunosuppression: The GRID randomized controlled trial

Charles-Hervé Vacheron, Alain Lepape, Fabienne Venet, Guillaume Monneret, Francois Gueyffier, Florent Boutitie...

Journal of Critical Care . 78 : 154330

DOI: 10.1016/j.jcrc.2023.154330

2023

Journal article

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An Overview of Regression Models for Adverse Events Analysis

Elsa Coz, Mathieu Fauvernier, Delphine Maucort-Boulch

Drug Safety .

DOI: 10.1007/s40264-023-01380-7

2023

Journal article

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Improved 30-Day Survival Estimation in ICU Patients: A Comparative Analysis of Different Approaches With Real-World Data

Charles-Hervé Vacheron, Arnaud Friggeri, Chloe Gerbaud-Coulas, Tristan Dagonneau, Jean Francois Timsit, Bernard Allaouchiche...

Critical Care Medicine .

DOI: 10.1097/CCM.0000000000006097

2023

Journal article

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A Multimodal Cardioprotection Strategy During Cardiac Surgery: The ProCCard Study

Pascal Chiari, Olivier Desebbe, Michel Durand, Marc-Olivier Fischer, Diane Lena-Quintard, Jean-Charles Palao...

Journal of Cardiothoracic and Vascular Anesthesia . 37 ( 8 ) : 1368-1376

DOI: 10.1053/j.jvca.2023.04.011

2023

Journal article

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Prognostic Value of Persistent CSF Antibodies at 12 Months in Anti-NMDAR Encephalitis

Nicolás Lundahl Ciano-Petersen, Mélisse Robert, Sergio Muñiz-Castrillo, Valentin Wucher, Amna Klich, Alberto Vogrig...

Neurology Neuroimmunology & Neuroinflammation . 10 ( 4 )

DOI: 10.1212/NXI.0000000000200108

2023

Journal article

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Prognostic impact of precipitated cardiac decompensation in symptomatic heart failure with reduced ejection fraction and severe secondary mitral regurgitation

Nathan Mewton, Erwan Donal, François Picard, François Derimay, Daniel Grinberg, Delphine Delphine Maucort Boulch...

American Heart Journal . 265 : 83-91

DOI: 10.1016/j.ahj.2023.05.016

2023

Journal article

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Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity

Antonio Farina, Cristina Birzu, Mad-Hélénie Elsensohn, Alberto Picca, Sergio Muñiz-Castrillo, Alberto Vogrig...

Brain Communications . 5 ( 3 )

DOI: 10.1093/braincomms/fcad169

2023

Journal article

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Prognostic Value of Persistent CSF Antibodies at 12 Months in Anti-NMDAR Encephalitis

Nicolás Lundahl Ciano-Petersen, Mélisse Robert, Sergio Muñiz-Castrillo, Valentin Wucher, Amna Klich, Alberto Vogrig...

Neurology Neuroimmunology & Neuroinflammation . 10 ( 4 ) : e200108

DOI: 10.1212/NXI.0000000000200108

2023

Journal article

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Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity

Antonio Farina, Cristina Birzu, Mad-Hélénie Elsensohn, Alberto Picca, Sergio Muñiz-Castrillo, Alberto Vogrig...

Brain Communications . 5 ( 3 ) : fcad169

DOI: 10.1093/braincomms/fcad169

2023

Journal article

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Monitoring multidimensional aspects of quality of life after cancer immunotherapy: protocol for the international multicentre, observational QUALITOP cohort study

Petra Vinke, Marc Combalia, Geertruida de Bock, Clémence Leyrat, Anne Mea Spanjaart, Stéphane Dalle...

BMJ Open . 13 ( 4 ) : e069090

DOI: 10.1136/bmjopen-2022-069090

2023

Journal article

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Statistics and Modelling for Health Sciences

Biostatistics Health Group

Evaluation and Modeling with the Therapeutic Effects Group

Publications

Effects of socioeconomic status on excess mortality in patients with multiple sclerosis in France: A retrospective observational cohort study

Influence of socio-economic status on excess mortality of multiple sclerosis

L’aspirine a-t-elle une place dans la prévention cardiovasculaire primaire par la polypill ? Étude de simulation sur une population virtuelle réaliste

Association between immune‐related adverse events and prognosis in patients treated with immune checkpoint inhibitors in melanoma: A surrogacy analysis

Heart and systemic sclerosis—findings from a national cohort study

Heart and systemic sclerosis—findings from a national cohort study

Incidence of infections in patients with psoriatic arthritis and axial spondyloarthritis treated with biological or targeted disease-modifying agents: a systematic review and meta-analysis of randomised controlled trials, open-label studies and observatio

Circulating microRNAs improve bacterial infection diagnosis and overall survival prediction in acute decompensation of liver cirrhosis

Platelet count threshold for hemorrhage in patients with immune thrombocytopenia treated with antiplatelet agents.

Patients’ perceptions on clinical trials outcomes in pulmonary arterial hypertension therapy

Circulating microRNAs improve bacterial infection diagnosis and overall survival prediction in acute decompensation of liver cirrhosis

Treatment strategy for acquired pure red cell aplasia: a systematic review and meta-analysis

Platelet count threshold for hemorrhage in patients with immune thrombocytopenia treated with antiplatelet agents

Immune thrombocytopenia and pregnancy: an exposed/nonexposed cohort study

AUC-based monitoring and model-informed precision dosing of vancomycin in critically ill patients: why and how?

Population Pharmacokinetics of Vancomycin in Patients Receiving Hemodialysis in a Malian and a French Center and Simulation of the Optimal Loading Dose

Evaluation of Limited Sampling Strategies for Bayesian Estimation of Daptomycin Area Under the Concentration–Time Curve: A Short Communication

From Personalized to Precision Medicine in Oncology: A Model-Based Dosing Approach to Optimize Achievement of Imatinib Target Exposure

Suboptimal exposure to fluconazole in critically ill patients: Pharmacokinetic analysis and determinants

Evaluation of Renal Impairment Influence on Metabolic Drug Clearance using a Modelling Approach

Granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients presenting sepsis-induced immunosuppression: The GRID randomized controlled trial

An Overview of Regression Models for Adverse Events Analysis

Improved 30-Day Survival Estimation in ICU Patients: A Comparative Analysis of Different Approaches With Real-World Data

A Multimodal Cardioprotection Strategy During Cardiac Surgery: The ProCCard Study

Prognostic Value of Persistent CSF Antibodies at 12 Months in Anti-NMDAR Encephalitis

Prognostic impact of precipitated cardiac decompensation in symptomatic heart failure with reduced ejection fraction and severe secondary mitral regurgitation

Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity

Prognostic Value of Persistent CSF Antibodies at 12 Months in Anti-NMDAR Encephalitis

Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity

Monitoring multidimensional aspects of quality of life after cancer immunotherapy: protocol for the international multicentre, observational QUALITOP cohort study

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