GECO Evolutionary and Computational Genomics

Bioinformatics, Phylogeny and Evolutionary Genomics Group

Baobab Group

The main goal of the GECO department is to foster integration and synergies between theoretical and methodological research relevant for the analysis of genomes (computational genomics) and empirical analysis of genomic and multi-omic data (evolutionary and functional genomics). The department is structured in two teams, BAOBAB and BPGE:

BAOBAB is deeply rooted in computer science. Its strengths are in algorithms, models, and mathematical analysis of graphs and networks, with applications to transcriptomics and metabolic networks.

BPGE is oriented towards bioinformatics, phylogenetics and evolutionary genomics. Its research projects cover a broad range of subjects, such as methodological developments for phylogenetic inference, their applications to the reconstruction of the evolutionary history of bacteria and archaea, the role of mobile genetic elements in the evolution of bacteria and of antibioresistance, or the role of recombination, of genomic rearrangements and of transposable elements in the evolution of eukaryotic genomes.

As detailed on their pages, the research conducted in both teams integrates deep and long-ranging theoretical and methodological (algorithmic and computational) developments with data analysis driven by empirical questions. This integration is bi-directional: methodological developments are guided by empirical questions and then used in empirical applications, while theoretical modeling helps clarify the conceptual basis of subsequent empirical analyses.

Publications

Display of 541 to 570 publications on 1402 in total

Microsporidian Genomes Harbor a Diverse Array of Transposable Elements that Demonstrate an Ancestry of Horizontal Exchange with Metazoans.

Nicolas Parisot, Adrian Pelin, Cyrielle Gasc, Valérie Polonais, Abdel Belkorchia, Johan Panek...

Genome Biology and Evolution . 6 ( 9 ) : 2289-300

DOI: 10.1093/gbe/evu178

Journal article

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Standard Sister Clade Comparison Fails when Testing Derived Character States

Jos Käfer, S. Mousset

Systematic Biology . 63 ( 4 ) : 601-609

DOI: 10.1093/sysbio/syu024

Journal article

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Exploiting the architecture and the features of the microsporidian genomes to investigate diversity and impact of these parasites on ecosystems

E Peyretaillade, D Boucher, N Parisot, C Gasc, R Butler, J-F Pombert...

Heredity . : 25182222

DOI: 10.1038/hdy.2014.78

Journal article

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An angiosperm-wide analysis of the gynodioecy-dioecy pathway.

Mathilde Dufaÿ, P. Champelovier, J Käfer, Jean-Pierre Henry, Sylvain Mousset, Gabriel A.B. Marais

Annals of Botany . 114 : 539-548

DOI: 10.1093/aob/mcu134

Journal article

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Comparative population genomics in animals uncovers the determinants of genetic diversity

Jonathan Romiguier, P Gayral, M Ballenghien, Arnaud Bernard, V Cahais, Anne Chenuil...

Nature . 515 ( 7526 ) : 261-263

DOI: 10.1038/nature13685

Journal article

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Phylogenomic test of the hypotheses for the evolutionary origin of eukaryotes

Nc. Rochette, Céline Brochier-Armanet, M. Gouy

Molecular Biology and Evolution . 31 ( 4 ) : 832-45

DOI: 10.1093/molbev/mst272

Journal article

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Fungal evolutionary genomics provides insight into the mechanisms of adaptive divergence in eukaryotes

Pierre P. Gladieux, Jeanne Ropars, Helene Badouin, Antoine Branca, Gabriela G. Aguileta, Damien M. de Vienne...

Molecular Ecology . 23 ( 4 ) : 753-773

DOI: 10.1111/mec.12631

Journal article

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Navigating in a Sea of Repeats in RNA-seq without Drowning

Gustavo Sacomoto, Blerina Sinaimeri, Camille Marchet, Vincent Miele, Marie-France Sagot, Vincent Lacroix

WABI 2014 - 14th International Workshop on Algorithms in Bioinformatics . 8701 : 82-96

DOI: 10.1007/978-3-662-44753-6_7

Conference paper

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Efficiently listing bounded length st-paths

Romeo Rizzi, Gustavo Sacomoto, Marie-France Sagot

Twenty-Fifth International Workshop on Combinatorial Algorithms (IWOCA 2014) . : in press

Conference paper

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Rime: Repeat identification

Maria Federico, Pierre Peterlongo, Nadia Pisanti, Marie-France Sagot

Discrete Applied Mathematics . 163 ( 3 ) : 275–286

DOI: 10.1016/j.dam.2013.02.016

Journal article

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Telling metabolic stories to explore metabolomics data: a case study on the yeast response to cadmium exposure

Paulo Vieira Milreu, Cecilia Coimbra Klein, Ludovic Cottret, Vicente Acuña, Etienne E. Birmelé, Michele Borassi...

Bioinformatics . 30 ( 1 ) : 61-70

DOI: 10.1093/bioinformatics/btt597

Journal article

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Optimization of the reactional medium and a food impact study for a colorimetric in situ Salmonella spp. detection method

L. Morand, D. Michel, Jean-Pierre Flandrois, T. Junillon, D. Mosticon, B. Mallen...

International Journal of Food Microbiology . 181 : 48-52

Journal article

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Enhanced tetrazolium violet reduction of Salmonella spp. by magnesium addition to the culture media

T. Junillon, L. Morand, Jean-Pierre Flandrois

Food Microbiology . 42 : 132-135

Journal article

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Ribosomal proteins: Toward a next generation standard for prokaryotic systematics?

Hemalatha Golaconda Ramulu, Mathieu Groussin, Emmanuel Talla, Rémi Planel, Vincent Daubin, Céline Brochier-Armanet

Molecular Phylogenetics and Evolution . 75 : 103 - 117

DOI: 10.1016/j.ympev.2014.02.013

Journal article

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Anaerobic oxidation of long-chain n-alkanes by the hyperthermophilic sulfate-reducing archaeon, Archaeoglobus fulgidus.

Nadia Khelifi, Oulfat Amin Ali, Philippe Roche, Vincent Grossi, Céline Brochier-Armanet, Odile Valette...

The International Society of Microbiologial Ecology Journal . : 18

DOI: 10.1038/ismej.2014.58

Journal article

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Halomonas olivaria sp. nov., a moderately halophilic bacterium isolated from olive-processing effluents

A. Amouric, Pierre-Pol Liebgott, M. Joseph, Céline Brochier-Armanet, J. Lorquin

International Journal of Systematic and Evolutionary Microbiology . 64 ( Pt 1 ) : 46 - 54

DOI: 10.1099/ijs.0.049007-0

Journal article

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Global phylogenomic analysis disentangles the complex evolutionary history of DNA replication in archaea.

Kasie Raymann, Patrick Forterre, Céline Brochier-Armanet, Simonetta Gribaldo

Genome Biology and Evolution . 6 ( 1 ) : 192-212

DOI: 10.1093/gbe/evu004

Journal article

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Evidence for Widespread Positive and Negative Selection in Coding and Conserved Noncoding Regions of Capsella grandiflora

Robert Williamson, Emily Josephs, Adrian Platts, Khaled Hazzouri, Annabelle A. Haudry, Mathieu Blanchette...

PLoS Genetics . 10 ( 9 )

DOI: 10.1371/journal.pgen.1004622

Journal article

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“One code to find them all”: a perl tool to conveniently parse RepeatMasker output files

Marc Bailly-Bechet, Annabelle Haudry, Emmanuelle Lerat

Mobile DNA . 5 : 13

DOI: 10.1186/1759-8753-5-13

Journal article

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Dioecy is associated with higher diversification rates in flowering plants

Jos Käfer, Hugo J de Boer, Sylvain Mousset, Anneleen Kool, Mathilde Dufaÿ, Gabriel A.B. Marais

Journal of Evolutionary Biology . 27 : 1478-1490

DOI: 10.1111/jeb.12385

Journal article

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Reductive genome evolution at both ends of bacterial population size spectrum

Bérénice Batut, Carole Knibbe, Gabriel Marais, Vincent Daubin

Nature Reviews Microbiology . 12 ( 12 ) : 841-850

DOI: 10.1038/nrmicro3331

Journal article

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Identification and Analysis of Transposable Elements in Genomic Sequences

Laurent Modolo, Emmanuelle Lerat

Genome analysis, current procedures and applications . 978-1-908230-29-4

Book chapter

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Formation of chromosome in bacteria

Olivier Poirion, Bénédicte Lafay

FEBS-EMBO 2014 Conference .

Conference paper

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A Haploid System of Sex Determination in the Brown Alga Ectocarpus sp.

Sophia S. Ahmed, J. Mark Cock, Eugenie Pessia, Remy Luthringer, Alexandre Cormier, Marine Robuchon...

Current Biology . 24 ( 17 ) : 1945-1957

DOI: 10.1016/j.cub.2014.07.042

Journal article

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Sex uncovered: the evolutionary biology of reproductive systems

T. Schwander, Gabriel Marais, D. Roze

Journal of Evolutionary Biology . 27 : 1287-91

Journal article

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Amortized Õ(|V|) -Delay Algorithm for Listing Chordless Cycles in Undirected Graphs

Rui Ferreira, Roberto Grossi, Romeo Rizzi, Gustavo Sacomoto, Marie-France Sagot

22th Annual European Symposium on Algorithms . 8737 : 418-429

DOI: 10.1007/978-3-662-44777-2_35

Conference paper

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Specific Activation of an I-Like Element in Drosophila Interspecific Hybrids

Elias a G Carnelossi, Emmanuelle Lerat, Hélène Henri, Sonia Martinez, Claudia M A Carareto, Cristina Vieira

Genome Biology and Evolution . 6 : 1806 - 1817

DOI: 10.1093/gbe/evu141

Journal article

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GC-Biased Gene Conversion in Yeast Is Specifically Associated with Crossovers: Molecular Mechanisms and Evolutionary Significance

Y. Lesecque, D. Mouchiroud, L. Duret

Molecular Biology and Evolution . 30 : 1409--19

DOI: 10.1093/molbev/mst056

Journal article

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XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells

C. Vallot, C. Huret, Yann Lesecque, A. Resch, N. Oudrhiri, A. Bennaceur-Griscelli...

Nature Genetics . 45 : 239--41

DOI: 10.1038/ng.2530

Journal article

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The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes

S. B. Montgomery, D. L. Goode, E. Kvikstad, C. A. Albers, Z. D. Zhang, X. J. Mu...

Genome Research . 23 : 749--61

DOI: 10.1101/gr.148718.112

Journal article

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