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Statistics and Modelling for Health Sciences
Evaluation and Modeling with the Therapeutic Effects Group
Tod Michel
Professeur d'université - praticien hospitalier émérite
UCBL
Publications
Display of 31 to 60 publications on 61 in total
A Prediction Model of Drug Exposure in Cirrhotic Patients According to Child-Pugh Classification
Clinical Pharmacokinetics . 54 : 1245-58
Journal article
see the publicationAntimicrobial-Related Severe Adverse Events during Treatment of Bone and Joint Infection Due to Methicillin-Susceptible Staphylococcus aureus
Antimicrobial Agents and Chemotherapy . 58 ( 2 ) : pp. 746-755
DOI: 10.1128/AAC.02032-13
Journal article
see the publicationHow to solve the problem of spontaneous bacterial clearance when testing new antibiotic treatment: results on experimental pneumonia due to a derepressed cephalosporinase-producing Enterobacter cloacae
Fundamental & Clinical Pharmacology . 27 ( 3 ) : 239-243
Journal article
see the publicationTheoretical investigation of the efficacy of antiangiogenic drugs combined to chemotherapy in xenografted mice.
Journal of Theoretical Biology . 320 : 86-99
Journal article
see the publicationImpact of Genetic Polymorphism on Drug-Drug Interactions Mediated by Cytochromes: A General Approach
AAPS journal . 15 : 1242--1252
Journal article
see the publicationIn Vivo Quantitative Prediction of the Effect of Gene Polymorphisms and Drug Interactions on Drug Exposure for CYP2C19 Substrates
AAPS Journal . 15 : 415-26
Journal article
see the publicationQuantitative Prediction of the Impact of Drug Interactions and Genetic Polymorphisms on Cytochrome P450 2C9 Substrate Exposure
Clinical Pharmacokinetics . 52 : 199-209
Journal article
see the publicationPharmacokinetic-pharmacodynamic modeling of unboosted Atazanavir in a cohort of stable HIV-infected patients.
Antimicrobial Agents and Chemotherapy . 57 ( 1 ) : 517-23
DOI: 10.1128/AAC.01822-12
Journal article
see the publicationProlonged subcutaneous high dose (1 g bid) of Ertapenem as salvage therapy in patients with difficult-to-treat bone and joint infection.
Journal of Infection . 65 ( 6 ) : 579-82
Journal article
see the publicationA Tumor Growth Inhibition Model for Low-Grade Glioma Treated with Chemotherapy or Radiotherapy.
Clinical Cancer Research . 18 ( 18 ) : 5071-5080
Journal article
see the publicationPrédiction quantitative des interactions médicamenteuses impliquant les cytochromes 3A4 et 2D6 : approche in vivo
La Lettre du Pharmacologue . 26 : 57--62
Journal article
see the publicationA pharmacodynamic model of ganciclovir antiviral effect and toxicity for lymphoblastoid cells suggests a new dosing regimen to treat cytomegalovirus infection
Antimicrobial Agents and Chemotherapy . 56 : 3732--8
DOI: 10.1128/AAC.06423-11
Journal article
see the publicationA Pharmacokinetic-Pharmacodynamic Model for Predicting the Impact of CYP2C9 and VKORC1 Polymorphisms on Fluindione and Acenocoumarol During Induction Therapy
Clinical Pharmacokinetics . 51 ( 1 ) : 41-53
Journal article
see the publicationModel-based design of rituximab dosing optimization in follicular non-hodgkin lymphoma
Fundamental & Clinical Pharmacology . 25 : 26-27
Journal article
see the publicationPharmacokinetic design optimization in children and estimation of maturation parameters: example of cytochrome P450 3A4
Journal of Pharmacokinetics and Pharmacodynamics . 38 ( 1 ) : 25 - 40
Journal article
see the publicationLinks between cyclosporin exposure in tissues and graft-versus-host disease in pediatric bone marrow transplantation: analysis by a PBPK model
Pharmaceutical Research . 28 : 531-539
Journal article
see the publicationGenotype-Based Quantitative Prediction of Drug Exposure for Drugs Metabolized by CYP2D6
Clinical Pharmacology and Therapeutics . 90 : 582-587
Journal article
see the publicationQuantitative prediction of cytochrome P450(CYP) 2D6-Mediated drug interactions
Clinical Pharmacokinetics . 50(8) : 519-530
Journal article
see the publicationA model of vascular tumour growth in mice combining longitudinal tumour size data with histological biomarkers.
European Journal of Cancer .
Journal article
see the publicationPredictive value of modeled AUC(AFP-hCG), a dynamic kinetic parameter characterizing serum tumor marker decline in patients with nonseminomatous germ cell tumor.
Urology . 76 ( 2 ) : 423-9.e2
Journal article
see the publicationPredictive values of hCG clearance for risk of methotrexate resistance in low-risk gestational trophoblastic neoplasias.
Annals of Oncology . 21 ( 8 ) : 1643-50
Journal article
see the publicationInfluence of dosing schedule on organ exposure to cyclosporin in pediatric hematopoietic stem cell transplantation: analysis with a PBPK model
Pharmaceutical Research . 27 : 2602-2613
Journal article
see the publication2009 - Development of a drug-disease simulation model for rituximab in follicular non-Hodgkin lymphoma
Congrès P2T (13ème congrès annuel de l a Société Française de Pharmacologie et de Thérapeutique .
Conference paper
see the publicationInvestigation of PK-PD drug-drug interaction between acenocoumarol and amoxicillin plus clavulanic acid.
Fundamental & Clinical Pharmacology . 23 ( 1 ) : 127-35
Journal article
see the publicationDevelopment of a drug-disease simulation model for rituximab in follicular non-Hodgkin's lymphoma
British Journal of Clinical Pharmacology . 68 ( 4 ) : 561-573
Journal article
see the publicationDevelopment of a drug - disease simulation model for rituximab in follicular non-Hodgkin lymphoma
Fundamental & Clinical Pharmacology . 23 : 49-50
Journal article
see the publicationChemotherapy may be delivered based on an integrated view of tumour dynamics.
IET Systems Biology . 3 ( 3 ) : 180-90
Journal article
see the publicationDevelopment of a drug - disease simulation model for rituximab in follicular non-Hodgkin lymphoma
Congrès P2T (13ème congrès annuel de la Sté Française de Pharmacologie et de Thérapeutique .
Conference paper
see the publicationEtoposide pharmacokinetics and survival in patients with small cell lung cancer: a multicentre study.
Lung Cancer . 62 ( 2 ) : 261-72
Journal article
see the publicationAdvantages of prostate-specific antigen (PSA) clearance model over simple PSA half-life computation to describe PSA decrease after prostate adenomectomy.
Clinical Biochemistry . 41 ( 10-11 ) : 785-95
Journal article
see the publication