Statistiques et Modélisation pour les Sciences de la Santé

Whole genome paired-end sequencing elucidates functional and phenotypic consequences of balanced chromosomal rearrangement in patients with developmental disorders

Caroline Schluth Schluth-Bolard, Flavie Diguet, Nicolas Chatron, Pierre-Antoine Rollat-Farnier, Claire Bardel, Alexandra Afenjar...

Journal of Medical Genetics . 56 ( 8 ) : 526-535

DOI: 10.1136/jmedgenet-2018-105778

2019

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Prevalence of infection among asymptomatic and paucisymptomatic contact persons exposed to Ebola virus in Guinea: a retrospective, cross-sectional observational study

Mamadou Saliou Kalifa Diallo, M. Rabilloud, Ahidjo Ayouba, Abdoulaye Touré, Guillaume Thaurignac, Alpha Kabinet Keita...

The Lancet Infectious Diseases . 19 ( 3 ) : 308-316

DOI: 10.1016/S1473-3099(18)30649-2

2019

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Significance of the CAPRI risk score to predict heart failure hospitalization post-TAVI: The CAPRI-HF study

Brahim Harbaoui, Eric Durand, Marion Dupré, Muriel Rabilloud, Geraud Souteyrand, Pierre-Yves Courand...

International Journal of Cardiology . 296 : 98-102

DOI: 10.1016/j.ijcard.2019.08.033

2019

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Quantifying Long-term Changes in Lung Function and Exacerbations after Initiation of Azithromycin in Cystic Fibrosis

Angélique Denis, Sandrine Touzet, Lamoussa Diabaté, Isabelle Durieu, Lydie Lemonnier, Stéphanie Poupon-Bourdy...

Annals of the American Thoracic Society .

DOI: 10.1513/AnnalsATS.201812-882OC

2019

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A Bayesian method to estimate the optimal threshold of a marker used to select patients' treatment

Yoann Blangero, Muriel Rabilloud, René Ecochard, Fabien Subtil

Statistical Methods in Medical Research . : 096228021882139

2019

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Subclinical Hypothyroidism: is it Really Subclinical with Aging?

A. Francois-Joubert, A. Vignoles, C. Ronin, M. Bonnefoy, R. Gourmelon, S. Donadio-Andrei...

Aging and disease . 10 ( 3 ) : 520--529

DOI: 10.14336/ad.2018.0817

2019

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Development of a Risk Score Based on Aortic Calcification to Predict 1-Year Mortality After Transcatheter Aortic Valve Replacement

Pierre Lantelme, Hélène Eltchaninoff, Muriel Rabilloud, Geraud Souteyrand, Marion Dupré, Marco Spaziano...

JACC: Cardiovascular Imaging . 12 ( 1 ) : 123-132

DOI: 10.1016/j.jcmg.2018.03.018

2019

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The contribution of genomics in the medicine of tomorrow, clinical applications and issues

Bruno Laviolle, Patrice Denèfle, François Gueyffier, Élodie Bégué, Pascal Bilbault, Helene Esperou...

Thérapie . 74 ( 1 ) : 9-15

DOI: 10.1016/j.therap.2018.11.012

2019

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Amikacin Initial Dose in Critically Ill Patients: a Nonparametric Approach To Optimize A Priori Pharmacokinetic/Pharmacodynamic Target Attainments in Individual Patients

Clément Boidin, Laurent Bourguignon, Sabine Cohen, Claire Roger, Jean-Yves Lefrant, Jason A. Roberts...

Antimicrobial Agents and Chemotherapy . 63 ( 11 ) : e00993-19

DOI: 10.1128/AAC.00993-19

2019

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Pharmacokinetic variability of beta-lactams in critically ill patients: A narrative review

Clément Boidin, Parastou Moshiri, Claire Dahyot-Fizelier, Sylvain Goutelle, Sandrine Lefeuvre

Anaesthesia Critical Care & Pain Medicine .

DOI: 10.1016/j.accpm.2019.07.016

2019

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Endoscopic mucosal resection with anchoring of the snare tip: multicenter retrospective evaluation of effectiveness and safety

Mathieu Pioche, Timothée Wallenhorst, Hugo Lepetit, Vincent Lépilliez, Jérôme Rivory, Romain Legros...

Endoscopy International Open . 07 : E1496 - E1502

DOI: 10.1055/a-0990-9068

2019

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Bench Assessment of the Effect of a Collapsible Tube on the Efficiency of a Mechanical Insufflation-Exsufflation Device

Romain Lachal, Bruno Louis, Fabien Subtil, Claude Guérin

Respiratory Care . 64 ( 7 ) : 752 - 759

DOI: 10.4187/respcare.06478

2019

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A simplified table using validated diagnostic criteria is effective to improve characterization of colorectal polyps: the CONECCT teaching program

Martin Fabritius, Jean-Michel Gonzalez, Aymeric Becq, Xavier Dray, Emmanuel Coron, Lucie Brenet-Defour...

Endoscopy International Open . 07 ( 10 ) : E1197-E1206

DOI: 10.1055/a-0962-9737

2019

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Acute Retinal Necrosis: Virological Features Using Quantitative Polymerase Chain Reaction, Therapeutic Management, and Clinical Outcomes

Meriem Hafidi, Hélène Janin-Manificat, Philippe Denis, Bruce Charleux, Muriel Rabilloud, Andre Boibieux...

American Journal of Ophthalmology . 208 : 376 - 386

DOI: 10.1016/j.ajo.2019.08.007

2019

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Bilateral adrenalectomy in Cushing's disease: Altered long-term quality of life compared to other treatment options

Pauline Sarkis, Muriel Rabilloud, Jean-Christophe Lifante, Anna Siamand, Emmanuel Jouanneau, Emmanuel Gay...

Annales d'Endocrinologie . 80 : 32 - 37

DOI: 10.1016/j.ando.2018.01.002

2019

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The limitations of observation studies for decision making regarding drugs efficacy and safety

François Gueyffier, Michel Cucherat

Alternative and Complementary Therapies . 74 ( 2 ) : 181-185

DOI: 10.1016/j.therap.2018.11.001

2019

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Do patients with cystic fibrosis participating in clinical trials demonstrate placebo response? A meta-analysis

Julie Coton, Ha-Hai Le, Victor Veuillet, Perrine Janiaud, Michel Cucherat, Behrouz Kassai-Koupai...

Journal of Cystic Fibrosis .

DOI: 10.1016/j.jcf.2019.02.003

2019

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Apport de la génomique dans la médecine de demain, applications cliniques et enjeux

Bruno Laviolle, Olivier Perche, François Gueyffier, Élodie Bégué, Pascal Bilbault, Hélène Esperou...

Thérapie . 74 ( 1 ) : 1-8

DOI: 10.1016/j.therap.2018.11.011

2019

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Immune system modelling in case of a septic shock

Jean Tallon, Françoise Couenne, Claire Bordes, Melaz Tayakout-Fayolle, Fabienne Venet, Guillaume Monneret...

29TH EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING, . : 1093-1098

DOI: 10.1016/B978-0-12-818634-3.50183-1

2019

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A 40 months follow-up of Ebola virus disease survivors in Guinea (Postebogui) reveals long-term detection of Ebola viral Ribonucleic Acid in semen and breast milk

Alpha Kabinet Keita, Nicole Vidal, Abdoulaye Touré, Mamadou Saliou Kalifa Diallo, N'Fally Magassouba, Sylvain Baize...

Open Forum Infectious Diseases . 6 ( 12 ) : ofz482

DOI: 10.1093/ofid/ofz482

2019

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Botulinum toxin for the treatment of hypercontractile esophagus: Results of a double‐blind randomized sham‐controlled study

Adrien Choné, Pietro Familiari, Burkhard von Rahden, Pankaj Desai, Haruhiro Inoue, Yuto Shimamura...

Neurogastroenterology & Motility . 31 ( 5 ) : e13587

DOI: 10.1111/nmo.13587

2019

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Multicenter Evaluation of Clinical Efficacy and Safety of Per-Oral Endoscopic Myotomy in Children

A. Chone, P. Familiari, B. Von Rahden, P. Desai, H. Inoue, Y. Shimamura...

Journal of Pediatric Gastroenterology and Nutrition .

DOI: 10.1097/mpg.0000000000002432

2019

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Compositional and mechanical properties of growing cortical bone tissue: a study of the human fibula

Emmanuelle Lefevre, Delphine Farlay, Yohann Barla, Fabien Subtil, Uwe Wolfram, Sébastien Rizzo...

Scientific Reports .

2019

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Obinutuzumab and ibrutinib induction therapy followed by a minimal residual disease-driven strategy in patients with chronic lymphocytic leukaemia (ICLL07 FILO): a single-arm, multicentre, phase 2 trial

Anne-Sophie Michallet, Marie-Sarah Dilhuydy, Fabien Subtil, Valérie Rouillé, Béatrice Mahé, Kamel Laribi...

The Lancet Haematology . 6 ( 9 ) : e470-e479

DOI: 10.1016/S2352-3026(19)30113-9

2019

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Use of prostate systematic and targeted biopsy on the basis of multiparametric MRI in biopsy-naive patients (MRI-FIRST): a prospective, multicentre, paired diagnostic study

Olivier Rouvière, Philippe Puech, Raphaele Renard-Penna, Michel Claudon, Catherine Roy, Florence Mège-Lechevallier...

Lancet Oncology . 20 ( 1 ) : 100-109

DOI: 10.1016/S1470-2045(18)30569-2

2019

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Identification of mobile retrocopies during genetic testing: Consequences for routine diagnosis

Nicolas Chatron, Kevin Cassinari, Olivier Quenez, Stéphanie Baert‐desurmont, Claire Bardel, Marie‐pierre Buisine...

Human Mutation . 40 ( 11 ) : 1993-2000

DOI: 10.1002/humu.23845

2019

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Single, short in-del, and copy number variations detection in monogenic dyslipidemia using a next-generation sequencing strategy

Oriane Marmontel, Sybil Charriere, T. Simonet, V. Bonnet, S. Dumont, M. Mahl...

Clinical Genetics . 94 ( 1 ) : 132-140

DOI: 10.1111/cge.13250

2018

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Effect of Optimal Medical Therapy at Discharge in Patients With Reperfused ST-Segment Elevation Myocardial Infarction on 1-Year Mortality (from the Regional RESCUe Registry)

Danka Tomasevic, Carlos El Khoury, Fabien Subtil, Pierre-Yves Dubien, Thomas Bochaton, Patrice Serre...

American Journal of Cardiology . 121 ( 4 ) : 403-409

DOI: 10.1016/j.amjcard.2017.11.002

2018

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Whole exome sequencing in three families segregating a pediatric case of sarcoidosis

Alain Calender, Pierre Antoine Rollat Farnier, Adrien Buisson, Stéphane Pinson, Abderrazzaq Bentaher, Serge Lebecque...

BMC Medical Genomics . 11 ( 1 ) : 23

DOI: 10.1186/s12920-018-0338-x

2018

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Variance component analysis to assess protein quantification in biomarker validation: Application to SRM mass spectrometry

Amna Klich, Catherine Mercier, Laurent Gerfault, Pierre Grangeat, Corinne Beaulieu, Elodie Degout-Charmette...

BMC Bioinformatics .

2018

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Statistiques et Modélisation pour les Sciences de la Santé

Equipe Biostatistiques Santé

Equipe Evaluation et Modélisation des Effets Thérapeutiques

Publications

Whole genome paired-end sequencing elucidates functional and phenotypic consequences of balanced chromosomal rearrangement in patients with developmental disorders

Prevalence of infection among asymptomatic and paucisymptomatic contact persons exposed to Ebola virus in Guinea: a retrospective, cross-sectional observational study

Significance of the CAPRI risk score to predict heart failure hospitalization post-TAVI: The CAPRI-HF study

Quantifying Long-term Changes in Lung Function and Exacerbations after Initiation of Azithromycin in Cystic Fibrosis

A Bayesian method to estimate the optimal threshold of a marker used to select patients' treatment

Subclinical Hypothyroidism: is it Really Subclinical with Aging?

Development of a Risk Score Based on Aortic Calcification to Predict 1-Year Mortality After Transcatheter Aortic Valve Replacement

The contribution of genomics in the medicine of tomorrow, clinical applications and issues

Amikacin Initial Dose in Critically Ill Patients: a Nonparametric Approach To Optimize A Priori Pharmacokinetic/Pharmacodynamic Target Attainments in Individual Patients

Pharmacokinetic variability of beta-lactams in critically ill patients: A narrative review

Endoscopic mucosal resection with anchoring of the snare tip: multicenter retrospective evaluation of effectiveness and safety

Bench Assessment of the Effect of a Collapsible Tube on the Efficiency of a Mechanical Insufflation-Exsufflation Device

A simplified table using validated diagnostic criteria is effective to improve characterization of colorectal polyps: the CONECCT teaching program

Acute Retinal Necrosis: Virological Features Using Quantitative Polymerase Chain Reaction, Therapeutic Management, and Clinical Outcomes

Bilateral adrenalectomy in Cushing's disease: Altered long-term quality of life compared to other treatment options

The limitations of observation studies for decision making regarding drugs efficacy and safety

Do patients with cystic fibrosis participating in clinical trials demonstrate placebo response? A meta-analysis

Apport de la génomique dans la médecine de demain, applications cliniques et enjeux

Immune system modelling in case of a septic shock

A 40 months follow-up of Ebola virus disease survivors in Guinea (Postebogui) reveals long-term detection of Ebola viral Ribonucleic Acid in semen and breast milk

Botulinum toxin for the treatment of hypercontractile esophagus: Results of a double‐blind randomized sham‐controlled study

Multicenter Evaluation of Clinical Efficacy and Safety of Per-Oral Endoscopic Myotomy in Children

Compositional and mechanical properties of growing cortical bone tissue: a study of the human fibula

Obinutuzumab and ibrutinib induction therapy followed by a minimal residual disease-driven strategy in patients with chronic lymphocytic leukaemia (ICLL07 FILO): a single-arm, multicentre, phase 2 trial

Use of prostate systematic and targeted biopsy on the basis of multiparametric MRI in biopsy-naive patients (MRI-FIRST): a prospective, multicentre, paired diagnostic study

Identification of mobile retrocopies during genetic testing: Consequences for routine diagnosis

Single, short in-del, and copy number variations detection in monogenic dyslipidemia using a next-generation sequencing strategy

Effect of Optimal Medical Therapy at Discharge in Patients With Reperfused ST-Segment Elevation Myocardial Infarction on 1-Year Mortality (from the Regional RESCUe Registry)

Whole exome sequencing in three families segregating a pediatric case of sarcoidosis

Variance component analysis to assess protein quantification in biomarker validation: Application to SRM mass spectrometry

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