Statistiques et Modélisation pour les Sciences de la Santé

A Model for Predicting the Interindividual Variability of Drug-Drug Interactions

M. Tod, Laurent Bourguignon, N. Bleyzac, Sylvain Goutelle

AAPS Journal . 19 : 497-509

DOI: 10.1208/s12248-016-0021-0

2017

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Dynamics of Ebola RNA Persistence in Semen: A Report From the Postebogui Cohort in Guinea

Fabien Subtil, Charlotte Delaunay, Alpha Kabinet Keita, Mamadou Saliou Sow, Abdoulaye Touré, Sandrine Leroy...

Clinical Infectious Diseases . 64 ( 12 ) : 1788 - 1790

DOI: 10.1093/cid/cix210

2017

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Cementless lateralized stems in primary THA: Mid-term survival and risk factors for failure in 172 stems

Cyril Courtin, Anthony Viste, Fabien Subtil, Olivier Catin, Romain Desmarchelier, Michel-Henri Fessy

Orthopaedics & Traumatology: Surgery & Research . 103 ( 1 ) : pp. 15-19

DOI: 10.1016/j.otsr.2016.10.011

2017

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Vancomycin treatment is a risk factor for vancomycin-nonsusceptible Staphylococcus capitis sepsis in preterm neonates

Marine Butin, Jean-Philippe Rasigade, F. Subtil, Patricia Martins-Simões, C. Pralong, A.-M. Freydière...

Clinical Microbiology and Infection . 23 ( 11 ) : 839-844

DOI: 10.1016/j.cmi.2017.03.022

2017

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Ibrutinib in very elderly patients with relapsed/refractory chronic lymphocytic leukemia: A real-world experience of 71 patients treated in France: A study from the French Innovative Leukemia Organization (FILO) group

Sophie Michallet, Arnaud Campidelli, Helene Lequeu, Marie-Sarah Dilhuydy, Olivier Tournilhac, Luc-Matthieu Fornecker...

American Journal of Hematology . 92 ( 6 ) : E105 - E107

DOI: 10.1002/ajh.24715

2017

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Evaluation of haemodialysis as a protective technique for preventing high daily dose amikacin nephrotoxicity: an experimental study in an ovine model.

Céline Pouzot Pouzot-Névoret, Mathieu Magnin, Jean-Yves Ayoub, Laurent Bourguignon, Pascal Maire, Damien Wertz...

International Journal of Antimicrobial Agents .

DOI: 10.1016/j.ijantimicag.2017.03.029

2017

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Restricted mean survival time over 15 years for patients starting renal replacement therapy

Cécile Couchoud, Emmanuelle Dantony, Mad-Hélénie Elsensohn, Emmanuel Villar, Cécile Vigneau, Olivier Moranne...

Nephrology Dialysis Transplantation . 32 ( Suppl.2 ) : ii60-ii67

DOI: 10.1093/ndt/gfw386

2017

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Reproducibility of in vivo magnetic resonance imaging T 1 rho and T 2 relaxation time measurements of hip cartilage at 3.0T in healthy volunteers

Angeline Nemeth, Lucy Di Marco, Florent Boutitie, Michael Sdika, Denis Grenier, Muriel Rabilloud...

Journal of Magnetic Resonance Imaging . 47 ( 4 ) : 1022-1033

DOI: 10.1002/jmri.25799

2017

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Efficacy and safety of DPP-4 inhibitors in patients with type 2 diabetes: Meta-analysis of placebo-controlled randomized clinical trials

M. Rehman, B.V. Tudrej, J. Soustre, M. Buisson, P. Archambault, D. Pouchain...

Diabetes & Metabolism . 43 ( 1 ) : 48 - 58

DOI: 10.1016/j.diabet.2016.09.005

2017

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No benefits of statins for sudden cardiac death prevention in patients with heart failure and reduced ejection fraction: A meta-analysis of randomized controlled trials

M. Al-Gobari, H.H. Le, M. Fall, François Gueyffier, B. Burnand

PLoS ONE . 12 : e0171168

DOI: 10.1371/journal.pone.0171168

2017

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Population pharmacokinetics of teicoplanin administered by subcutaneous or intravenous route and simulation of optimal loading dose regimen

Yoann Cazaubon, Nicolas Venisse, Olivier Mimoz, Pascal Maire, Michel Ducher, Laurent Bourguignon...

Journal of Antimicrobial Chemotherapy . 72 ( 10 ) : 2804-2812

DOI: 10.1093/jac/dkx242

2017

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Mechanisms of drug-drug interaction between rifampicin and fusidic acid

Florianne Bel, Laurent Bourguignon, Michel Tod, Tristan Ferry, Sylvain Goutelle

British Journal of Clinical Pharmacology . 83 ( 8 ) : 1862-1864

DOI: 10.1111/bcp.13277

2017

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A Nonparametric Method to Optimize Initial Drug Dosing and Attainment of a Target Exposure Interval: Concepts and Application to Busulfan in Pediatrics

M. Philippe, M. Neely, Y. Bertrand, N. Bleyzac, Sylvain Goutelle

Clinical Pharmacokinetics . 56 : 435-447

DOI: 10.1007/s40262-016-0448-6

2017

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Prevalence and Risk Factors of Drug-Associated Corrected QT Prolongation in Elderly Hospitalized Patients: Results of a Retrospective Analysis of Data Obtained Over 6 Months

O. Maison, B. de La Gastine, L. Dayot, Sylvain Goutelle

Drugs & aging . 34 : 545-553

DOI: 10.1007/s40266-017-0467-5

2017

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Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study

Charles R G Guttmann, Matthieu Rousset, Jean-Amédée Roch, Salem Hannoun, Françoise Durand-Dubief, Boubakeur Belaroussi...

Multiple Sclerosis Journal . 22 ( 6 ) : 761 - 769

DOI: 10.1177/1352458515600247

2016

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Introduction of a paediatric anaesthesia comic information leaflet reduced preoperative anxiety in children

B. Kassai, Muriel Rabilloud, E. Dantony, S. Grousson, O. Revol, S. Malik...

British Journal of Anaesthesia . 117 : 95-102

DOI: 10.1093/bja/aew154

2016

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Accuracy of several maternal seric markers for predicting histological chorioamnionitis after preterm premature rupture of membranes: a prospective and multicentric study

J. Caloone, Muriel Rabilloud, F. Boutitie, A. Traverse-Glehen, F. Allias-Montmayeur, L. Denis...

European Journal of Obstetrics & Gynecology and Reproductive Biology . 205 : 133-40

DOI: 10.1016/j.ejogrb.2016.08.022

2016

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Comparison of the Schwartz and CKD-EPI Equations for Estimating Glomerular Filtration Rate in Children, Adolescents, and Adults: A Retrospective Cross-Sectional Study

L. Selistre, Muriel Rabilloud, P. Cochat, V. de Souza, J. Iwaz, S. Lemoine...

PLoS Medicine . 13 : e1001979

DOI: 10.1371/journal.pmed.1001979

2016

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Placental histological lesions in fetal and neonatal alloimmune thrombocytopenia: A retrospective cohort study of 21 cases

E. Dubruc, F. Lebreton, C. Giannoli, Muriel Rabilloud, C. Huissoud, M. Devouassoux-Shisheboran...

Placenta . 48 : 104-109

DOI: 10.1016/j.placenta.2016.10.009

2016

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Early diagnosis of gestational trophoblastic neoplasia based on trajectory classification with compartment modeling

C. Burny, Muriel Rabilloud, F. Golfier, J. Massardier, T. Hajri, A. M. Schott...

BMC Medical Research Methodology . 16 : 3

DOI: 10.1186/s12874-015-0106-y

2016

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Reduced bone volumetric density and weak correlation between infection and bone markers in cystic fibrosis adult patients

D. Gensburger, S. Boutroy, R. Chapurlat, R. Nove-Josserand, S. Roche, Muriel Rabilloud...

Osteoporosis International . 27 : 2803-13

DOI: 10.1007/s00198-016-3612-9

2016

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Prone position and VAP incidence in the PROSEVA trial: attention to the causal question when interpreting competing risk analysis-response to comments by Ranzani et al.

Muriel Rabilloud, C. Guérin

Intensive Care Medicine . 42 : 2121-2122

DOI: 10.1007/s00134-016-4548-4

2016

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Quality of qualitative studies centred on patients in family practice: a systematic review

Benedicte Eschalier, Stéphane Descamps, Bruno Pereira, Hélène Vaillant-Roussel, Guillaume Girard, Stéphane Boisgard...

Family Practice . 33 ( 6 ) : 580 - 587

DOI: 10.1093/fampra/cmw095

2016

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Référentiel ECRIN pour la conformité aux bonnes pratiques de gestion des données des essais cliniques multinationaux

Catherine Cornu, Anne Donche, Carine Coffre, Amélie Le Gouge, Boulkedid Rym, Isabelle Vaugier...

Thérapie .

DOI: 10.2515/therapie/2015042

2016

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Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers

L. Gabriel, M. Tod, Sylvain Goutelle

Clinical Pharmacokinetics . 55 : 977-990

DOI: 10.1007/s40262-016-0371-x

2016

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Familial vs. sporadic sarcoidosis: BTNL2 polymorphisms, clinical presentations, and outcomes in a French cohort

Yves Pacheco, Alain Calender, Dominique Israël-Biet, Pascal Roy, Serge Lebecque, Vincent Cottin...

Orphanet Journal of Rare Diseases . 11 ( 1 ) : np

DOI: 10.1186/s13023-016-0546-4

2016

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A bench evaluation of fraction of oxygen in air delivery and tidal volume accuracy in home care ventilators available for hospital use

L. Baboi, Fabien Subtil, C. Guerin

Journal of Thoracic Disease . 8 ( 12 ) : 3639-3647

DOI: 10.21037/jtd.2016.12.64

2016

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Le médecin généraliste face à la prise en charge de « l’allergie au médicament » : un éclairage sur la pratique actuelle en région Rhône-Alpes, et perspectives d’amélioration

V.-A. Huynh, E. Lungoci, Audrey Nosbaum, Florence Hacard, F. Subtil, Jean-François Nicolas...

Revue francaise d'allergologie . 56 ( 5 ) : 401-406

DOI: 10.1016/j.reval.2016.02.007

2016

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kmlShape: An Efficient Method to Cluster Longitudinal Data (Time-Series) According to Their Shapes

Christophe Genolini, René Ecochard, Mamoun Benghezal, Driss Tarak, Sandrine Andrieu, Fabien Subtil

PLoS ONE . 11 ( 6 )

DOI: 10.1371/journal.pone.0150738

2016

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Accurately Achieving Target Busulfan Exposure in Children and Adolescents With Very Limited Sampling and the BestDose Software

M. Neely, M. Philippe, T. Rushing, X. Fu, M. van Guilder, D. Bayard...

Therapeutic Drug Monitoring . 38 : 332-342

DOI: 10.1097/FTD.0000000000000276

2016

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Statistiques et Modélisation pour les Sciences de la Santé

Equipe Biostatistiques Santé

Equipe Evaluation et Modélisation des Effets Thérapeutiques

Publications

A Model for Predicting the Interindividual Variability of Drug-Drug Interactions

Dynamics of Ebola RNA Persistence in Semen: A Report From the Postebogui Cohort in Guinea

Cementless lateralized stems in primary THA: Mid-term survival and risk factors for failure in 172 stems

Vancomycin treatment is a risk factor for vancomycin-nonsusceptible Staphylococcus capitis sepsis in preterm neonates

Ibrutinib in very elderly patients with relapsed/refractory chronic lymphocytic leukemia: A real-world experience of 71 patients treated in France: A study from the French Innovative Leukemia Organization (FILO) group

Evaluation of haemodialysis as a protective technique for preventing high daily dose amikacin nephrotoxicity: an experimental study in an ovine model.

Restricted mean survival time over 15 years for patients starting renal replacement therapy

Reproducibility of in vivo magnetic resonance imaging T 1 rho and T 2 relaxation time measurements of hip cartilage at 3.0T in healthy volunteers

Efficacy and safety of DPP-4 inhibitors in patients with type 2 diabetes: Meta-analysis of placebo-controlled randomized clinical trials

No benefits of statins for sudden cardiac death prevention in patients with heart failure and reduced ejection fraction: A meta-analysis of randomized controlled trials

Population pharmacokinetics of teicoplanin administered by subcutaneous or intravenous route and simulation of optimal loading dose regimen

Mechanisms of drug-drug interaction between rifampicin and fusidic acid

A Nonparametric Method to Optimize Initial Drug Dosing and Attainment of a Target Exposure Interval: Concepts and Application to Busulfan in Pediatrics

Prevalence and Risk Factors of Drug-Associated Corrected QT Prolongation in Elderly Hospitalized Patients: Results of a Retrospective Analysis of Data Obtained Over 6 Months

Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study

Introduction of a paediatric anaesthesia comic information leaflet reduced preoperative anxiety in children

Accuracy of several maternal seric markers for predicting histological chorioamnionitis after preterm premature rupture of membranes: a prospective and multicentric study

Comparison of the Schwartz and CKD-EPI Equations for Estimating Glomerular Filtration Rate in Children, Adolescents, and Adults: A Retrospective Cross-Sectional Study

Placental histological lesions in fetal and neonatal alloimmune thrombocytopenia: A retrospective cohort study of 21 cases

Early diagnosis of gestational trophoblastic neoplasia based on trajectory classification with compartment modeling

Reduced bone volumetric density and weak correlation between infection and bone markers in cystic fibrosis adult patients

Prone position and VAP incidence in the PROSEVA trial: attention to the causal question when interpreting competing risk analysis-response to comments by Ranzani et al.

Quality of qualitative studies centred on patients in family practice: a systematic review

Référentiel ECRIN pour la conformité aux bonnes pratiques de gestion des données des essais cliniques multinationaux

Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers

Familial vs. sporadic sarcoidosis: BTNL2 polymorphisms, clinical presentations, and outcomes in a French cohort

A bench evaluation of fraction of oxygen in air delivery and tidal volume accuracy in home care ventilators available for hospital use

Le médecin généraliste face à la prise en charge de « l’allergie au médicament » : un éclairage sur la pratique actuelle en région Rhône-Alpes, et perspectives d’amélioration

kmlShape: An Efficient Method to Cluster Longitudinal Data (Time-Series) According to Their Shapes

Accurately Achieving Target Busulfan Exposure in Children and Adolescents With Very Limited Sampling and the BestDose Software

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