Evolutionary Ecology

Quantitative and Evolutionary Ecology of Communities Group

Delignette-Muller Marie-Laure

Professeure des universités

VetAgro-Sup

Address: 69280 MARCY L'ÉTOILE

Tel: 33 04 72 43 27 56

Email

I am a Professor at VetAgro Sup, responsible for various modules of biostatistics at the veterinary curriculum, a module of critical reading of articles and co-leader of a module of Bayesian statistics mutualized between the three masters piloted by the LBBE. Some of my teaching documents are available on my personal web page.

My research activity is in the field of biometrics. I develop models and inference methods in the context of risk assessment in the field of health and environmental risks. My objective is to propose models/methods useful to researchers to better understand risks, and useful to managers to define risk indicators. My areas of expertise are: hierarchical models, non-linear models, dose-response models, in particular dose-response modeling of omics data, Bayesian inference.

In order to facilitate the use of the methods I develop to the largest number of people, I am involved in the development of various R packages: fitdistrplus, nlstools, DRomics.

My publications are listed exhaustively on my Google Scholar profile and my most recent papers are available on my HAL CV.

Publications

Display of 1 to 30 publications on 87 in total

Interpretation of the results of ELISA tests commercialized for the serological diagnosis of Coxiella burnetii infection in domestic ruminants: a user-friendly Shiny application based on latent class models in a Bayesian framework

T. Lurier, Marie Laure Delignette-Muller, Florence Ayral, Elsa Jourdain, Elodie Rousset

31st WORLD BUIATRICS CONGRESS .

Conference paper

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Evaluation using latent class models of the diagnostic performances of three ELISA tests commercialized for the serological diagnosis of Coxiella burnetii infection in domestic ruminants

T. Lurier, Elodie Rousset, Patrick Gasqui, Carole Sala, Clément Claustre, David Abrial...

31st WORLD BUIATRICS CONGRESS .

Conference paper

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Interpretation of the results of Q fever ELISA tests in domestic ruminants : a user-friendly Shiny appli-cation based on latent class models in a Bayesian framework

T. Lurier, Marie Laure Delignette-Muller, Elsa Jourdain, Florence Ayral, Elodie Rousset

ESCCAR International congress on Rickettsiae and 9th Meeting of the European Society for Chlamydia Research (ESCR) .

Conference paper

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Evaluation using latent class models of the diagnostic performances of three ELISA tests commercialized for the serological diagnosis of Coxiella burnetii infection in domestic ruminants

T. Lurier, Elodie Rousset, Patrick Gasqui, Carole Sala, Clément Claustre, David Abrial...

ESCCAR International congress on Rickettsiae and 9th Meeting of the European Society for Chlamydia Research (ESCR) . : #231

Poster

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Coxiella burnetii within- and between-herd true seroprevalence assessment in domestic ruminants in France accounting for diagnostic uncertainty with latent class

T. Lurier, Elodie Rousset, Carole Sala, Kristel Gache, Marie Laure Delignette-Muller, Elsa Jourdain...

ESCCAR International congress on Rickettsiae and 9th Meeting of the European Society for Chlamydia Research (ESCR) . : #232

Poster

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How does interspecific competition modify the response of grass plants against herbicide treatment? A hierarchical concentration-response approach

Vincent Baillard, Marie Laure Delignette-Muller, Cécile Sulmon, Anne‐kristel Bittebière, Cendrine Mony, Ivan Couée...

Science of the Total Environment . 778 : 146108

DOI: 10.1016/j.scitotenv.2021.146108

Journal article

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Evaluation using latent class models of the diagnostic performances of three ELISA tests commercialized for the serological diagnosis of Coxiella burnetii infection in domestic ruminants

Thibaut Lurier, Elodie Rousset, Patrick Gasqui, Carole Sala, Eric Morignat, Clément Claustre...

Gemeinsamen Arbeitstagung der Nationalen Referenzlabore Chlamydiose, Q-Fieber, Paratuberkulose und Tuberkulose der Rinder - Online-Tagung veranstaltet . : 17 slides

Conference paper

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Evaluation using latent class models of the diagnostic performances of three ELISA tests commercialized for the serological diagnosis of Coxiella burnetii infection in domestic ruminants

Thibaut Lurier, Elodie Rousset, Patrick Gasqui, Carole Sala, Clément Claustre, David Abrial...

Veterinary Research . 52 ( 1 )

DOI: 10.1186/s13567-021-00926-w

Journal article

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Evaluation, à l’aide de modèles à classes latentes, des performances diagnostic des tests ELISA commercialisés pour le diagnostic sérologique des infections par Coxiella burnetii chez les ruminants domestiques

T. Lurier, Elodie Rousset, Patrick Gasqui, Carole Sala, Clément Caustre, David Abrial...

17ème Rencontre des Microbiologistes du Pôle Clermontois .

Conference paper

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A multi-omics concentration-response framework uncovers novel understanding of triclosan effects in the chlorophyte Scenedesmus vacuolatus

Floriane Larras, Elise Billoir, Stefan Scholz, Mika Tarkka, Tesfaye Wubet, Marie-Laure Delignette-Muller...

Journal of Hazardous Materials . 397 : 122727

DOI: 10.1016/j.jhazmat.2020.122727

Journal article

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Developmental variability channels mouse molar evolution

Luke Hayden, Katerina Lochovska, Marie Sémon, Sabrina Renaud, Marie-Laure Delignette-Muller, Maurine Vilcot...

eLife .

DOI: 10.7554/eLife.50103

Journal article

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Effect of interspecific competition on species sensitivity distribution models: Analysis of plant responses to chemical stress

Vincent Baillard, Cécile Sulmon, Anne‐kristel Bittebière, Cendrine Mony, Ivan Couée, Gwenola Gouesbet...

Ecotoxicology and Environmental Safety . 200 : 110722

DOI: 10.1016/j.ecoenv.2020.110722

Journal article

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Approche de Modélisation Hiérarchique pour la Description de l'Effet de la Compétition Interspécifique sur la Tolérance Chimique d'Herbacées

Vincent Baillard, Marie Laure Delignette-Muller, Cécile Sulmon, Anne‐kristel Bittebière, Cendrine Mony, Simon Devin...

SEFA 2019 Lyon .

Conference paper

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Outils d'observation des boiteries

Valentin Poulain, Luc Mounier, Marie-Laure Delignette Muller, Dorothee Ledoux

Journées Nationales des Groupements Techniques Vétérinaires (JNGTV) . : np

Poster

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Importance de la variabilité intraspécifique de la polluosensibilité pour l’évaluation du risque ecotoxicologique basée sur l’approche SSD (Species Sensitivity Distribution)

Vincent Baillard, Laurine Malardier, Marie Laure Delignette-Muller, Eva Roubeau Dumont, Arnault Elger, Agnes Bouchez...

38ème colloque de l’Association des Diatomistes de Langue Française (ADLaF) .

Conference paper

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Diagnosis of bovine dictyocaulosis by bronchoalveolar lavage technique: A comparative study using a Bayesian approach

T. Lurier, Marie Laure Delignette-Muller, B. Rannou, C. Strube, Marie-Anne Arcangioli, G. Bourgoin

Preventive Veterinary Medicine .

Journal article

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Evaluation de méthodes diagnostiques en l’absence de gold standard sur la base de variables binaires et continues : intérêt de l'approche bayésienne

Thibaut Lurier, Marie-Laure Delignette Muller, Elsa Jourdain, Florence Ayral

Journée AppliBUGS . : 38 slides

Conference paper

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MOSAIC: a web-interface for statistical analyses in ecotoxicology

Sandrine Charles, Philippe Veber, Marie Laure Delignette-Muller

Environmental Science and Pollution Research . 25 ( 12 ) : 11295-11302

DOI: 10.1007/s11356-017-9809-4

Journal article

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Assessment of Ozone or Not-Treated Wastewater Ecotoxicity Using Mechanism-Based and Zebrafish Embryo Bioassays

Adriana Wigh, Selim Ait-Aissa, Nicolas Creusot, Hugo Terrisse, Marie Laure Delignette-Muller, Alexandre Bergé...

Journal of Environmental Protection . 09 ( 04 ) : 325 - 346

DOI: 10.4236/jep.2018.94022

Journal article

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DRomics: A Turnkey Tool to Support the Use of the Dose–Response Framework for Omics Data in Ecological Risk Assessment

Floriane Larras, Elise Billoir, Vincent Baillard, Aurélie Siberchicot, Stefan Scholz, Tesfaye Wubet...

Environmental Science and Technology . 52 ( 24 ) : 14461-14468

DOI: 10.1021/acs.est.8b04752

Journal article

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Response to Comment on "Robust Fit of Toxicokinetic-Toxicodynamic Models Using Prior Knowledge Contained in the Design of Survival Toxicity Tests

Marie Laure Delignette-Muller, P. Veber

Environmental Science and Technology . 51 : 8202-8203

DOI: 10.1021/acs.est.7b02548

Journal article

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Robust Fit of Toxicokinetic-Toxicodynamic Models Using Prior Knowledge Contained in the Design of Survival Toxicity Tests

Marie Laure Delignette-Muller, P. Ruiz, P. Veber

Environmental Science and Technology . 51 : 4038-4045

DOI: 10.1021/acs.est.6b05326

Journal article

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Analysis of hemocytes in Lymnaea stagnalis: Characterization and effects of repeated hemolymph collections

Paul Boisseaux, Marie Laure Delignette-Muller, Khédidja Abbaci, Hélène Thomas, Jeanne Garric

Fish and Shellfish Immunology . 57 : 116-126

DOI: 10.1016/j.fsi.2016.08.007

Journal article

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Recommendations for the analysis of hemocyte-related immunocompetent oxidative activity in the freshwater snail Lymnaea stagnalis

P. Boisseaux, P. Noury, Marie Laure Delignette-Muller, H. Thomas, J. Garric

Journal of Xenobiotics . 6 : 25-27

DOI: 10.4081/xeno.2016.6585

Journal article

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fitdistrplus : An R Package for Fitting Distributions

Marie Laure Delignette-Muller, Christophe Dutang

Journal of Statistical Software . 64 ( 4 )

DOI: 10.18637/jss.v064.i04

Journal article

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Constructing Time-Resolved Species Sensitivity Distributions Using a Hierarchical Toxico-Dynamic Model

Guillaume Kon Kam King, Marie Laure Delignette-Muller, Ben J. Kefford, Christophe Piscart, Sandrine Charles

Environmental Science and Technology . 49 ( 20 ) : 12465-12473

DOI: 10.1021/acs.est.5b02142

Journal article

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A Toolbox for Nonlinear Regression in R: The Package nistools

F. Baty, C. Ritz, Sandrine Charles, M. Brutsche, Jean-Pierre Flandrois, Marie Laure Delignette-Muller

Journal of Statistical Software . 66 : 1-21

Journal article

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MOSAIC_SSD: A new web tool for species sensitivity distribution to include censored data by maximum likelihood

Guillaume Kon Kam King, Philippe Veber, Sandrine Charles, Marie Laure Delignette-Muller

Ecotoxicology and Environmental Safety . 33 ( 9 ) : 2133 - 2139

DOI: 10.1002/etc.2644

Journal article

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Hierarchical modelling of species sensitivity distribution: development and application to the case of diatoms exposed to several herbicides

Guillaume Kon Kam King, Floriane Larras, Sandrine Charles, Marie Laure Delignette-Muller

Ecotoxicology and Environmental Safety . 114 : 212-221

DOI: 10.1016/j.ecoenv.2015.01.022

Journal article

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Statistical handling of reproduction data for exposure-response modeling

Marie Laure Delignette-Muller, Christelle Lopes, Philippe Veber, Sandrine Charles

Environmental Science and Technology . 48 : 7544-51

DOI: 10.1021/es502009r

Journal article

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