
Statistics and Modelling for Health Sciences
Evaluation and Modeling with the Therapeutic Effects Group
Goutelle Sylvain
Professeur d'université - praticien hospitalier
UCBL
Publications
Display of 1 to 30 publications on 56 in total
Daptomycin Physiology-Based Pharmacokinetic Modeling to Predict Drug Exposure and Pharmacodynamics in Skin and Bone Tissues
Clinical Pharmacokinetics . 61 ( 10 ) : 1443-1456
Journal article
see the publicationImplementation of Model-Based Dose Adjustment of Tobramycin in Adult Patients with Cystic Fibrosis
Pharmaceutics . 14 ( 8 ) : 1750
Journal article
see the publicationSeventeen Cases of Daptomycin-Induced Eosinophilic Pneumonia in a Cohort of Patients Treated for Bone and Joint Infections: Proposal for a New Algorithm
Open Forum Infectious Diseases . 9 ( 11 ) : ofac577
DOI: 10.1093/ofid/ofac577
Journal article
see the publicationAn Investigation of O-Demethyl Tramadol/Tramadol Ratio for Cytochrome P450 2D6 Phenotyping: The CYTRAM Study
Pharmaceutics . 14 ( 10 ) : 2177
Journal article
see the publicationPopulation pharmacokinetics of daptomycin in patients with bone and joint infection: minimal effect of rifampicin co-administration and confirmation of a sex difference
Journal of Antimicrobial Chemotherapy . 76 ( 5 ) : 1250-1257
DOI: 10.1093/jac/dkab006
Journal article
see the publicationModel-Based Comparative Analysis of Rifampicin and Rifabutin Drug-Drug Interaction Profile
Antimicrobial Agents and Chemotherapy . 65 ( 9 ) : e0104321
DOI: 10.1128/AAC.01043-21
Journal article
see the publicationPopulation Pharmacokinetics and Dosing Simulation of Vancomycin Administered by Continuous Injection in Critically Ill Patient
Antibiotics . 10 ( 10 ) : 1228
Journal article
see the publicationRifampicin exposure reveals within-host Mycobacterium tuberculosis diversity in patients with delayed culture conversion
PLoS Pathogens . 17 ( 6 ) : e1009643
Journal article
see the publicationAmikacin Initial Dose in Critically Ill Patients: a Nonparametric Approach To Optimize A Priori Pharmacokinetic/Pharmacodynamic Target Attainments in Individual Patients
Antimicrobial Agents and Chemotherapy . 63 ( 11 ) : e00993-19
DOI: 10.1128/AAC.00993-19
Journal article
see the publicationPharmacokinetic variability of beta-lactams in critically ill patients: A narrative review
Anaesthesia Critical Care & Pain Medicine .
Journal article
see the publicationProspective Cohort Study of the Tolerability of Prosthetic Joint Infection Empirical Antimicrobial Therapy
ANTIMICROB. AGENTS CHEMOTHER. . 62 ( 10 )
DOI: 10.1128/AAC.00163-18
Journal article
see the publicationAntituberculous drugs modulate bacterial phagolysosome avoidance and autophagy in Mycobacterium tuberculosis-infected macrophages
Tuberculosis . 111 : 67-70
Journal article
see the publicationAssessing the Combined Antibacterial Effect of Isoniazid and Rifampin on Four Mycobacterium tuberculosis Strains Using In Vitro Experiments and Response-Surface Modeling
Antimicrobial Agents and Chemotherapy . 62 ( 1 )
DOI: 10.1128/AAC.01413-17
Journal article
see the publicationThe Role of Antibiotics in Modulating Virulence in Staphylococcus aureus
Clinical Microbiology Reviews . 30 ( 4 ) : 887-917
DOI: 10.1128/CMR.00120-16
Journal article
see the publicationIs Trough Concentration of Vancomycin Predictive of the Area Under the Curve? A Clinical Study in Elderly Patients
Therapeutic Drug Monitoring . 39 : 83-87
Journal article
see the publicationImplications of using the MDRD or CKD-EPI equation instead of the Cockcroft-Gault equation for estimating renal function and drug dosage adjustment in elderly patients
Fundamental & Clinical Pharmacology . 31 : 110-119
DOI: 10.1111/fcp.12241
Journal article
see the publicationA Model for Predicting the Interindividual Variability of Drug-Drug Interactions
AAPS Journal . 19 : 497-509
Journal article
see the publicationPopulation pharmacokinetics of teicoplanin administered by subcutaneous or intravenous route and simulation of optimal loading dose regimen
Journal of Antimicrobial Chemotherapy . 72 ( 10 ) : 2804-2812
DOI: 10.1093/jac/dkx242
Journal article
see the publicationMechanisms of drug-drug interaction between rifampicin and fusidic acid
British Journal of Clinical Pharmacology . 83 ( 8 ) : 1862-1864
DOI: 10.1111/bcp.13277
Journal article
see the publicationA Nonparametric Method to Optimize Initial Drug Dosing and Attainment of a Target Exposure Interval: Concepts and Application to Busulfan in Pediatrics
Clinical Pharmacokinetics . 56 : 435-447
Journal article
see the publicationPrevalence and Risk Factors of Drug-Associated Corrected QT Prolongation in Elderly Hospitalized Patients: Results of a Retrospective Analysis of Data Obtained Over 6 Months
Drugs & aging . 34 : 545-553
Journal article
see the publicationQuantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers
Clinical Pharmacokinetics . 55 : 977-990
Journal article
see the publicationAccurately Achieving Target Busulfan Exposure in Children and Adolescents With Very Limited Sampling and the BestDose Software
Therapeutic Drug Monitoring . 38 : 332-342
Journal article
see the publicationShould busulfan therapeutic range be narrowed in pediatrics? Experience from a large cohort of hematopoietic stem cell transplant children
Bone Marrow Transplantation . 51 : 72-78
DOI: 10.1038/bmt.2015.218
Journal article
see the publicationMathematical modeling and systems pharmacology of tuberculosis: Isoniazid as a case study
Journal of Theoretical Biology . 399 : 43-52
Journal article
see the publicationPharmacokinetic Variability of Daptomycin during Prolonged Therapy for Bone and Joint Infections
Antimicrobial Agents and Chemotherapy . 60 ( 5 ) : pp. 3148-3151
DOI: 10.1128/AAC.02597-15
Journal article
see the publicationComparison of the static in vivo approach to a physiologically based pharmacokinetic approach for metabolic drug-drug interactions prediction
International Journal of Pharmacokinetics . : 1-10
Journal article
see the publicationModel-Based Determination of Effective Blood Concentrations of Cyclosporine for Neutrophil Response in the Treatment of Severe Aplastic Anemia in Children
AAPS Journal . 17 ( 5 ) : 1157-67
Journal article
see the publicationPopulation modeling and simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of isoniazid in lungs
Antimicrobial Agents and Chemotherapy . 59 ( 9 ) : 5181-5189
DOI: 10.1128/AAC.00462-15
Journal article
see the publicationSubcutaneous administration of levetiracetam in geriatrics
Revue Neurologique . 171 : 398-399
Journal article
see the publication